Search Results - "Konkwo, Chigoziri"

Genomic analysis of lean individuals with NAFLD identifies monogenic disorders in a prospective cohort study by Zheng, Melanie, Huang, Daniel Q., Konkwo, Chigoziri, Agrawal, Saaket, Khera, Amit V., Loomba, Rohit, Vilarinho, Sílvia, Ajmera, Veeral

“…Lean patients with non-alcoholic fatty liver disease (NAFLD) represent 10–20% of the affected population and may have heterogeneous drivers of disease. We have…”
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Provider-identified barriers to performance at seven Nigerian accident & emergency units: A cross-sectional study by Muhammad, Muzzammil Imran, Umoga, Kelechi, Acquaye, Amber, Fleischer, Brian, Konkwo, Chigoziri, Ogunyemi, Kehinde Olawale, Ngaruiya, Christine

“…Nigeria hosts much of Africa's morbidity and mortality from emergency medical conditions. We surveyed providers at seven Nigerian Accident & Emergency (A&E)…”
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Almajiri health; a scoping review on disease, health literacy and space for participatory research by Muhammad, Muzzammil Imran, Abdulsalam, Amna Hassana, Petit-Clair, Fadhina, Acquaye, Amber, Nobles, Autumn, Fleischer, Brian, Konkwo, Chigoziri, Ransome, Yusuf, Paintsil, Elijah

“…INTRODUCTIONAlmajirai are male children in Northern Nigeria and Southern Niger who study Islam in the almajiranci system. Almajiranci has been associated with…”
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Introduction by Baskerville, Maia, Konkwo, Chigoziri

“…The incidence of allergic disease is on the rise across the globe, marked by increases in related healthcare expenses and mortality, as well as significant…”
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Introduction by Baskerville, Maia, Konkwo, Chigoziri

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Imeglimin: Current Development and Future Potential in Type 2 Diabetes by Konkwo, Chigoziri, Perry, Rachel J.

“…Imeglimin is the first of the “glimins,” a new class of drugs developed for the treatment of type 2 diabetes mellitus (T2DM). This review highlights its…”
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Rare and Undiagnosed Liver Diseases: New Insights From Genomic and Single Cell Transcriptomic Analyses by Konkwo, Chigoziri

“…Chronic liver disease (CLD) is a major global health problem, leading to an estimated two million annual deaths worldwide. Advances in next generation…”
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Genetics of liver disease in adults by Konkwo, Chigoziri, Chowdhury, Shanin, Vilarinho, Silvia

“…Chronic liver disease stands as a significant global health problem with an estimated 2 million annual deaths across the globe. Combining the use of…”
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Revisiting the Exhibits—Medical Student Reflections on Changes to the Institutional Portraiture at a US Medical School by Konkwo, Chigoziri, Fitzsousa, Elizabeth, Chan, Shin Mei, Muhammad, Muzzammil, Anderson, Nientara, Reisman, Anna

“…Background Yale School of Medicine’s (YSM) Sterling Hall of Medicine (SHM) has historically been lined with large oil paintings of mostly White men, despite…”
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Combinatorial glucose, nicotinic acid and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease by Guha, Sujay, Mathew, Neal D, Konkwo, Chigoziri, Ostrovsky, Julian, Kwon, Young Joon, Polyak, Erzsebet, Seiler, Christoph, Bennett, Michael, Xiao, Rui, Zhang, Zhe, Nakamaru-Ogiso, Eiko, Falk, Marni J

“…Abstract Mitochondrial respiratory chain disorders are empirically managed with variable antioxidant, cofactor and vitamin ‘cocktails’. However, clinical trial…”
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Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease by Guha, Sujay, Konkwo, Chigoziri, Lavorato, Manuela, Mathew, Neal D, Peng, Min, Ostrovsky, Julian, Kwon, Young-Joon, Polyak, Erzsebet, Lightfoot, Richard, Seiler, Christoph, Xiao, Rui, Bennett, Michael, Zhang, Zhe, Nakamaru-Ogiso, Eiko, Falk, Marni J

“…Abstract Cysteamine bitartrate is a US Food and Drug Administration-approved therapy for nephropathic cystinosis also postulated to enhance glutathione…”
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Advancing diagnosis and management of liver disease in adults through exome sequencing by Zheng, Melanie, Hakim, Aaron, Konkwo, Chigoziri, Deaton, Aimee M., Ward, Lucas D., Silveira, Marina G., Assis, David N., Liapakis, AnnMarie, Jaffe, Ariel, Jiang, Z. Gordon, Curry, Michael P., Lai, Michelle, Cho, Michael H., Dykas, Daniel, Bale, Allen, Mistry, Pramod K., Vilarinho, Silvia

“…Whole-exome sequencing (WES) is an effective tool for diagnosis in patients who remain undiagnosed despite a comprehensive clinical work-up. While WES is being…”
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Advancing diagnosis and management of liver disease in adults through exome sequencingResearch in context by Melanie Zheng, Aaron Hakim, Chigoziri Konkwo, Aimee M. Deaton, Lucas D. Ward, Marina G. Silveira, David N. Assis, AnnMarie Liapakis, Ariel Jaffe, Z. Gordon Jiang, Michael P. Curry, Michelle Lai, Michael H. Cho, Daniel Dykas, Allen Bale, Pramod K. Mistry, Silvia Vilarinho

“…Background: Whole-exome sequencing (WES) is an effective tool for diagnosis in patients who remain undiagnosed despite a comprehensive clinical work-up. While…”
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