Search Results - "Koning, Harry"

The drugs of sleeping sickness: Their mechanisms of action and resistance, and a brief history by P De Koning, Harry

“…With the incidence of sleeping sickness in decline and genuine progress being made towards the WHO goal of eliminating sleeping sickness as a major public…”
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Risk prediction models for selection of lung cancer screening candidates: A retrospective validation study by Ten Haaf, Kevin, Jeon, Jihyoun, Tammemägi, Martin C, Han, Summer S, Kong, Chung Yin, Plevritis, Sylvia K, Feuer, Eric J, de Koning, Harry J, Steyerberg, Ewout W, Meza, Rafael

“…Selection of candidates for lung cancer screening based on individual risk has been proposed as an alternative to criteria based on age and cumulative smoking…”
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Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up by Schröder, Fritz H, Prof, Hugosson, Jonas, Prof, Roobol, Monique J, PhD, Tammela, Teuvo L J, Prof, Zappa, Marco, MD, Nelen, Vera, MD, Kwiatkowski, Maciej, MD, Lujan, Marcos, MD, Määttänen, Liisa, PhD, Lilja, Hans, Prof, Denis, Louis J, Prof, Recker, Franz, Prof, Paez, Alvaro, MD, Bangma, Chris H, Prof, Carlsson, Sigrid, MD, Puliti, Donella, MSc, Villers, Arnauld, MD, Rebillard, Xavier, MD, Hakama, Matti, Prof, Stenman, Ulf-Hakan, Prof, Kujala, Paula, MD, Taari, Kimmo, MD, Aus, Gunnar, MD, Huber, Andreas, Prof, van der Kwast, Theo H, Prof, van Schaik, Ron H N, Prof, de Koning, Harry J, Prof, Moss, Sue M, Prof, Auvinen, Anssi, Prof

“…Summary Background The European Randomised study of Screening for Prostate Cancer (ERSPC) has shown significant reductions in prostate cancer mortality after 9…”
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Performance and Cost-Effectiveness of Computed Tomography Lung Cancer Screening Scenarios in a Population-Based Setting: A Microsimulation Modeling Analysis in Ontario, Canada by Ten Haaf, Kevin, Tammemägi, Martin C, Bondy, Susan J, van der Aalst, Carlijn M, Gu, Sumei, McGregor, S Elizabeth, Nicholas, Garth, de Koning, Harry J, Paszat, Lawrence F

“…The National Lung Screening Trial (NLST) results indicate that computed tomography (CT) lung cancer screening for current and former smokers with three annual…”
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Population screening for liver fibrosis: Toward early diagnosis and intervention for chronic liver diseases by Ginès, Pere, Castera, Laurent, Lammert, Frank, Graupera, Isabel, Serra‐Burriel, Miquel, Allen, Alina M., Wong, Vincent Wai‐Sun, Hartmann, Phillipp, Thiele, Maja, Caballeria, Llorenç, Knegt, Robert J., Grgurevic, Ivica, Augustin, Salvador, Tsochatzis, Emmanuel A., Schattenberg, Jörn M., Guha, Indra Neil, Martini, Andrea, Morillas, Rosa M., Garcia‐Retortillo, Montserrat, Koning, Harry J., Fabrellas, Núria, Pich, Judit, Ma, Ann T., Diaz, M. Alba, Roulot, Dominique, Newsome, Philip N., Manns, Michael, Kamath, Patrick S., Krag, Aleksander

“…Cirrhosis, highly prevalent worldwide, develops after years of hepatic inflammation triggering progressive fibrosis. Currently, the main etiologies of…”
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Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes by Baker, Nicola, Glover, Lucy, Munday, Jane C, Aguinaga Andrés, David, Barrett, Michael P, de Koning, Harry P, Horn, David

“…African trypanosomes cause sleeping sickness in humans, a disease that is typically fatal without chemotherapy. Unfortunately, drug resistance is common and…”
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Effect of organised cervical cancer screening on cervical cancer mortality in Europe: a systematic review by Jansen, Erik E.L., Zielonke, Nadine, Gini, Andrea, Anttila, Ahti, Segnan, Nereo, Vokó, Zoltán, Ivanuš, Urška, McKee, Martin, de Koning, Harry J., de Kok, Inge M.C.M., Veerus, Piret, Anttila, Ahti, Heinävaara, Sirpa, Sarkeala, Tytti, Csanádi, Marcell, Pitter, Janos, Széles, György, Vokó, Zoltán, Minozzi, Silvia, Segnan, Nereo, Senore, Carlo, van Ballegooijen, Marjolein, Driesprong - de Kok, Inge, Gini, Andrea, Heijnsdijk, Eveline, Jansen, Erik, de Koning, Harry, Lansdorp – Vogelaar, Iris, van Ravesteyn, Nicolien, Zielonke, Nadine, Ivanus, Urska, Jarm, Katja, Mlakar, Dominika Novak, Primic-Žakelj, Maja, McKee, Martin, Priaulx, Jennifer

“…Organised cervical cancer (CC) screening programmes are delivered in many different ways across the European Union and its regions. Our aim was to…”
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Purine and pyrimidine transporters of pathogenic protozoa – conduits for therapeutic agents by Campagnaro, Gustavo D., Koning, Harry P.

“…Purines and pyrimidines are essential nutrients for any cell. Most organisms are able to synthesize their own purines and pyrimidines, but this ability was…”
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Impact of colorectal cancer screening on cancer-specific mortality in Europe: A systematic review by Gini, Andrea, Jansen, Erik E.L., Zielonke, Nadine, Meester, Reinier G.S., Senore, Carlo, Anttila, Ahti, Segnan, Nereo, Mlakar, Dominika Novak, de Koning, Harry J., Lansdorp-Vogelaar, Iris, Veerus, Piret, Anttila, Ahti, Heinävaara, Sirpa, Sarkeala, Tytti, Csanádi, Marcell, Pitter, Janos, Széles, György, Vokó, Zoltán, Minozzi, Silvia, Segnan, Nereo, Senore, Carlo, van Ballegooijen, Marjolein, Driesprong - de Kok, Inge, Gini, Andrea, Heijnsdijk, Eveline, Jansen, Erik, de Koning, Harry, Lansdorp – Vogelaar, Iris, van Ravesteyn, Nicolien, Zielonke, Nadine, Ivanus, Urska, Jarm, Katja, Mlakar, Dominika Novak, Primic-Žakelj, Maja, McKee, Martin, Priaulx, Jennifer

“…Populations differ with respect to their cancer risk and screening preferences, which may influence the performance of colorectal cancer (CRC) screening…”
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Evaluation of the Benefits and Harms of Lung Cancer Screening With Low-Dose Computed Tomography: Modeling Study for the US Preventive Services Task Force by Meza, Rafael, Jeon, Jihyoun, Toumazis, Iakovos, ten Haaf, Kevin, Cao, Pianpian, Bastani, Mehrad, Han, Summer S, Blom, Erik F, Jonas, Daniel E, Feuer, Eric J, Plevritis, Sylvia K, de Koning, Harry J, Kong, Chung Yin

“…IMPORTANCE: The US Preventive Services Task Force (USPSTF) is updating its 2013 lung cancer screening guidelines, which recommend annual screening for adults…”
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The Activity of Red Nigerian Propolis and Some of Its Components against Trypanosoma brucei and Trypanosoma congolense by Alenezi, Samya S, Alenezi, Naif D, Ebiloma, Godwin U, Natto, Manal J, Ungogo, Marzuq A, Igoli, John O, Ferro, Valerie A, Gray, Alexander I, Fearnley, James, Koning, Harry P de, Watson, David G

“…Propolis is a resin that is gathered by bees from exudates produced by various plants. Its exact chemical composition depends on the plants available near the…”
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Prostate-Cancer Mortality at 11 Years of Follow-up by Schröder, Fritz H, Hugosson, Jonas, Roobol, Monique J, Tammela, Teuvo L.J, Ciatto, Stefano, Nelen, Vera, Kwiatkowski, Maciej, Lujan, Marcos, Lilja, Hans, Zappa, Marco, Denis, Louis J, Recker, Franz, Páez, Alvaro, Määttänen, Liisa, Bangma, Chris H, Aus, Gunnar, Carlsson, Sigrid, Villers, Arnauld, Rebillard, Xavier, van der Kwast, Theodorus, Kujala, Paula M, Blijenberg, Bert G, Stenman, Ulf-Hakan, Huber, Andreas, Taari, Kimmo, Hakama, Matti, Moss, Sue M, de Koning, Harry J, Auvinen, Anssi

“…The European Randomized Study of Screening for Prostate Cancer continues to show a 21% reduction in prostate-cancer mortality in the screening group, after 11…”
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The animal trypanosomiases and their chemotherapy: a review by Giordani, Federica, Morrison, Liam J, Rowan, Tim G, DE Koning, Harry P, Barrett, Michael P

“…Pathogenic animal trypanosomes affecting livestock have represented a major constraint to agricultural development in Africa for centuries, and their negative…”
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Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story by Baker, Nicola, de Koning, Harry P, Mäser, Pascal, Horn, David

“…Melarsoprol and pentamidine represent the two main classes of drugs, the arsenicals and diamidines, historically used to treat the diseases caused by African…”
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Evidence for reducing cancer-specific mortality due to screening for breast cancer in Europe: A systematic review by Zielonke, Nadine, Gini, Andrea, Jansen, Erik E.L., Anttila, Ahti, Segnan, Nereo, Ponti, Antonio, Veerus, Piret, de Koning, Harry J., van Ravesteyn, Nicolien T., Heijnsdijk, Eveline A.M., Veerus, Piret, Anttila, Ahti, Heinävaara, Sirpa, Sarkeala, Tytti, Cañada, Marcell, Pitter, Janos, Széles, György, Voko, Zoltan, Minozzi, Silvia, Segnan, Nereo, Senore, Carlo, van Ballegooijen, Marjolein, Driesprong - de Kok, Inge, Gini, Andrea, Heijnsdijk, Eveline, Jansen, Erik, de Koning, Harry, Lansdorp – Vogelaar, Iris, van Ravesteyn, Nicolien, Zielonke, Nadine, Ivanus, Urska, Jarm, Katja, Mlakar, Dominika Novak, Primic-Žakelj, Maja, McKee, Martin, Priaulx, Jennifer

“…The aim of this study was to quantify the impact of organised mammography screening on breast cancer mortality across European regions. Therefore, a systematic…”
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Personalising lung cancer screening: An overview of risk‐stratification opportunities and challenges by Haaf, Kevin, Aalst, Carlijn M., Koning, Harry J., Kaaks, Rudolf, Tammemägi, Martin C.

“…Randomised clinical trials have shown the efficacy of computed tomography lung cancer screening, initiating discussions on whether and how to implement…”
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Lung cancer probability in patients with CT-detected pulmonary nodules: a prespecified analysis of data from the NELSON trial of low-dose CT screening by Horeweg, Nanda, Dr, van Rosmalen, Joost, PhD, Heuvelmans, Marjolein A, van der Aalst, Carlijn M, PhD, Vliegenthart, Rozemarijn, PhD, Scholten, Ernst Th, MD, ten Haaf, Kevin, MSc, Nackaerts, Kristiaan, PhD, Lammers, Jan-Willem J, Prof, Weenink, Carla, MD, Groen, Harry J, Prof, van Ooijen, Peter, PhD, de Jong, Pim A, PhD, de Bock, Geertruida H, PhD, Mali, Willem, Prof, de Koning, Harry J, Prof, Oudkerk, Matthijs, Prof

“…Summary Background The main challenge in CT screening for lung cancer is the high prevalence of pulmonary nodules and the relatively low incidence of lung…”
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Detection of lung cancer through low-dose CT screening (NELSON): a prespecified analysis of screening test performance and interval cancers by Horeweg, Nanda, Dr, Scholten, Ernst Th, MD, de Jong, Pim A, PhD, van der Aalst, Carlijn M, PhD, Weenink, Carla, MD, Lammers, Jan-Willem J, Prof, Nackaerts, Kristiaan, PhD, Vliegenthart, Rozemarijn, PhD, ten Haaf, Kevin, MSc, Yousaf-Khan, Uraujh A, MD, Heuvelmans, Marjolein A, Thunnissen, Erik, PhD, Oudkerk, Matthijs, Prof, Mali, Willem, Prof, de Koning, Harry J, Prof

“…Summary Background Low-dose CT screening is recommended for individuals at high risk of developing lung cancer. However, CT screening does not detect all lung…”
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Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial by de Koning, Harry J, van der Aalst, Carlijn M, de Jong, Pim A, Scholten, Ernst T, Nackaerts, Kristiaan, Heuvelmans, Marjolein A, Lammers, Jan-Willem J, Weenink, Carla, Yousaf-Khan, Uraujh, Horeweg, Nanda, van ’t Westeinde, Susan, Prokop, Mathias, Mali, Willem P, Mohamed Hoesein, Firdaus A.A, van Ooijen, Peter M.A, Aerts, Joachim G.J.V, den Bakker, Michael A, Thunnissen, Erik, Verschakelen, Johny, Vliegenthart, Rozemarijn, Walter, Joan E, ten Haaf, Kevin, Groen, Harry J.M, Oudkerk, Matthijs

“…High-risk persons were screened for lung cancer in a population-based, randomized, controlled trial that involved volume-based nodule management for further…”
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Occurrence and lung cancer probability of new solid nodules at incidence screening with low-dose CT: analysis of data from the randomised, controlled NELSON trial by Walter, Joan E, BSc, Heuvelmans, Marjolein A, PhD, de Jong, Pim A, PhD, Vliegenthart, Rozemarijn, Prof, van Ooijen, Peter M A, PhD, Peters, Robin B, MD, ten Haaf, Kevin, MSc, Yousaf-Khan, Uraujh, MD, van der Aalst, Carlijn M, PhD, de Bock, Geertruida H, Prof, Mali, Willem, Prof, Groen, Harry J M, Prof, de Koning, Harry J, Prof, Oudkerk, Matthijs, Prof

“…Summary Background US guidelines now recommend lung cancer screening with low-dose CT for high-risk individuals. Reports of new nodules after baseline…”
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