Search Results - "Kong, Yahui"
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ANRIL : A lncRNA at the CDKN2A/B Locus With Roles in Cancer and Metabolic Disease
Published in Frontiers in endocrinology (Lausanne) (24-07-2018)“…The genomic locus is associated with risk of human cancers and metabolic disease. Although the locus contains several important protein-coding genes, studies…”
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Notch3 Functions as a Tumor Suppressor by Controlling Cellular Senescence
Published in Cancer research (Chicago, Ill.) (01-06-2013)“…Notch signaling regulates a broad spectrum of cell fate decisions and differentiation. Both oncogenic and tumor suppressor functions have been shown for Notch…”
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High-throughput analysis of ANRIL circRNA isoforms in human pancreatic islets
Published in Scientific reports (11-05-2022)“…The a ntisense n on-coding R NA in the I NK l ocus ( ANRIL ) is a hotspot for genetic variants associated with cardiometabolic disease. We recently found…”
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4
Daily Flood Monitoring Based on Spaceborne GNSS-R Data: A Case Study on Henan, China
Published in Remote sensing (Basel, Switzerland) (01-11-2021)“…Flood is a kind of natural disaster that is extremely harmful and occurs frequently. To reduce losses caused by the hazards, it is urgent to monitor the…”
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CDKN2A/B T2D Genome-Wide Association Study Risk SNPs Impact Locus Gene Expression and Proliferation in Human Islets
Published in Diabetes (New York, N.Y.) (01-05-2018)“…Genome-wide association studies link the locus with type 2 diabetes (T2D) risk, but mechanisms increasing risk remain unknown. The locus encodes cell cycle…”
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Smurf2‐mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence
Published in Aging cell (01-12-2011)“…Summary The inhibitor of differentiation or DNA binding (Id) family of transcription regulators plays an important role in cell proliferation, differentiation,…”
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Experiment for Oil Spill Detection Based on Dual-Frequency QZSS Reflected Signals Using Drone-Borne GNSS-R
Published in Remote sensing (Basel, Switzerland) (01-07-2024)“…Oil spill detection plays an important role in marine environment protection. The technique of global navigation satellite system-reflectometry (GNSS-R) has…”
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Smurf2 Regulates the Senescence Response and Suppresses Tumorigenesis in Mice
Published in Cancer research (Chicago, Ill.) (01-06-2012)“…The E3 ubiquitin ligase Smurf2 mediates ubiquitination and degradation of several protein targets involved in tumorigenesis and induces senescence in human…”
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Regulation of Senescence in Cancer and Aging
Published in Journal of Aging Research (2011)“…Senescence is regarded as a physiological response of cells to stress, including telomere dysfunction, aberrant oncogenic activation, DNA damage, and oxidative…”
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10
Smurf2 regulates hematopoietic stem cell self‐renewal and aging
Published in Aging cell (01-06-2014)“…Summary The age‐dependent decline in the self‐renewal capacity of stem cells plays a critical role in aging, but the precise mechanisms underlying this decline…”
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Preparation and Properties of Poly(amidoamine) Dendrimer/Quaternary Ammonium Chitosan Hydrogels
Published in Journal of Wuhan University of Technology. Materials science edition (01-06-2018)“…A novel quaternary ammonium chitosan hydrogel modified by poly(amidoamine) (PAMAM) dendrimer was prepared by using glutaraldehyde as a cross-linker. The…”
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12
Oxidative Stress, Mitochondrial Dysfunction, and Aging
Published in Journal of Signal Transduction (2012)“…Aging is an intricate phenomenon characterized by progressive decline in physiological functions and increase in mortality that is often accompanied by many…”
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Preparation and properties of quaternary ammonium chitosan-g-poly(acrylic acid-co-acrylamide) superabsorbent hydrogels
Published in Reactive & functional polymers (01-02-2017)“…Quaternary ammonium chitosan-g-poly(acrylic acid-co-acrylamide) superabsorbent hydrogels were successfully synthesized from acrylic acid (AA), acrylamide (AM)…”
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14
Oxidative stress, mitochondrial dysfunction and the mitochondria theory of aging
Published in Interdisciplinary topics in gerontology (01-01-2014)“…Aging is characterized by a progressive decline in cellular function, organismal fitness and increased risk of age-associated diseases and death. One potential…”
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Islet biology, the CDKN2A/B locus and type 2 diabetes risk
Published in Diabetologia (01-08-2016)“…Type 2 diabetes, fuelled by the obesity epidemic, is an escalating worldwide cause of personal hardship and public cost. Diabetes incidence increases with age,…”
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Analysis of Drone-Based GNSS-R Soil Moisture Retrieval From QZSS GEO L5-Band Signal
Published in IEEE geoscience and remote sensing letters (2024)“…Currently, soil moisture (SM) is mostly measured by conventional contact methods, such as dry weighing and time domain reflectometry (TDR). Global navigation…”
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Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor
Published in Diabetes (New York, N.Y.) (01-04-2016)“…An important goal in diabetes research is to understand the processes that trigger endogenous β-cell proliferation. Hyperglycemia induces β-cell replication,…”
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Abstract 1239: Smurf2-mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract The cyclin-dependent kinase inhibitor p16INK4A (p16) plays a critical role in senescence, cancer and aging. Its expression increases in senescent…”
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Smurf2 suppresses B-cell proliferation and lymphomagenesis by mediating ubiquitination and degradation of YY1
Published in Nature communications (2013)“…About half of patients with diffuse large B-cell lymphoma (DLBCL) do not respond to or relapse soon after the standard chemotherapy, indicating a critical need…”
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Preparation and antibacterial properties of O-carboxymethyl chitosan/lincomycin hydrogels
Published in Journal of biomaterials science. Polymer ed. (01-01-2016)“…In this study, O-carboxymethyl chitosan (O-CMCS) was synthesized from chitosan and monochloroacetic acid. Then O-CMCS hydrogel was prepared by…”
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