Search Results - "Kong, Siyuan"

GproDIA enables data-independent acquisition glycoproteomics with comprehensive statistical control by Yang, Yi, Yan, Guoquan, Kong, Siyuan, Wu, Mengxi, Yang, Pengyuan, Cao, Weiqian, Qiao, Liang

“…Large-scale profiling of intact glycopeptides is critical but challenging in glycoproteomics. Data independent acquisition (DIA) is an emerging technology with…”
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Targeting protein glycosylation to regulate inflammation in the respiratory tract: novel diagnostic and therapeutic candidates for chronic respiratory diseases by Xie, Xiaofeng, Kong, Siyuan, Cao, Weiqian

“…Protein glycosylation is a widespread posttranslational modification that can impact the function of proteins. Dysregulated protein glycosylation has been…”
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Preparation and Adsorption Properties of Graphene-Modified, Pitch-Based Carbon Foam Composites by Li, Hao, Li, Tiehu, Deng, Weibin, Kong, Siyuan

“…In view of the good adsorption properties of graphene and carbon foam, they were combined to achieve the optimal matching of microstructures. Taking mesophase…”
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pGlycoQuant with a deep residual network for quantitative glycoproteomics at intact glycopeptide level by Kong, Siyuan, Gong, Pengyun, Zeng, Wen-Feng, Jiang, Biyun, Hou, Xinhang, Zhang, Yang, Zhao, Huanhuan, Liu, Mingqi, Yan, Guoquan, Zhou, Xinwen, Qiao, Xihua, Wu, Mengxi, Yang, Pengyuan, Liu, Chao, Cao, Weiqian

“…Large-scale intact glycopeptide identification has been advanced by software tools. However, tools for quantitative analysis remain lagging behind, which…”
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Overexpression of miRNA29a gene inhibits proliferation and promotes apoptosis of jejunal epithelial cells in yak by Jia, Jianlei, Zuo, Erwei, Li, Ning, Kong, Siyuan, Bao, Pengjia, Chen, Qian, Yan, Ping

“…MicroRNAs (miRNAs) were identified to be involved in various biological functions by regulating the degradation or suppressing the translation of their…”
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Single-cell omics: A new direction for functional genetic research in human diseases and animal models by Kong, Siyuan, Li, Rongrong, Tian, Yunhan, Zhang, Yaqiu, Lu, Yuhui, Ou, Qiaoer, Gao, Peiwen, Li, Kui, Zhang, Yubo

“…Over the past decade, with the development of high-throughput single-cell sequencing technology, single-cell omics has been emerged as a powerful tool to…”
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Global Transcriptomic Profiling of Cardiac Hypertrophy and Fatty Heart Induced by Long-Term High-Energy Diet in Bama Miniature Pigs by Xia, Jihan, Zhang, Yuanyuan, Xin, Leilei, Kong, Siyuan, Chen, Yaoxing, Yang, Shulin, Li, Kui

“…A long-term high-energy diet affects human health and leads to obesity and metabolic syndrome in addition to cardiac steatosis and hypertrophy. Ectopic fat…”
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Circulating proteomic panels for risk stratification of intracranial aneurysm and its rupture by Xiong, Yueting, Zheng, Yongtao, Yan, Yan, Yao, Jun, Liu, Hebin, Shen, Fenglin, Kong, Siyuan, Yang, Shuang, Yan, Guoquan, Zhao, Huanhuan, Zhou, Xinwen, Hu, Jia, Zhou, Bin, Jin, Tao, Shen, Huali, Leng, Bing, Yang, Pengyuan, Liu, Xiaohui

“…The prevalence of intracranial aneurysm (IA) is increasing, and the consequences of its rupture are severe. This study aimed to reveal specific, sensitive, and…”
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Effect of Phenolic Resin on Micropores Development in Carbon Foam with High Performance by Dang, Alei, Zhao, Zhao, Tang, Chen, Fang, Chenglin, Kong, Siyuan, Khan, Muhammad, Li, Tiehu, Zhao, Tingkai, Li, Hao

“…A novel high-performance carbon foam (CF) was fabricated through the addition of phenolic resin (PR) into a coal tar pitch (CTP) based precursor. The effects…”
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Transcriptome analysis on the inflammatory cell infiltration of nonalcoholic steatohepatitis in bama minipigs induced by a long-term high-fat, high-sucrose diet by Xia, Jihan, Yuan, Jing, Xin, Leilei, Zhang, Yuanyuan, Kong, Siyuan, Chen, Yaoxing, Yang, Shulin, Li, Kui

“…Long-term adherence to a high-fat, high-calorie diet influences human health and causes obesity, metabolic syndrome and nonalcoholic steatohepatitis (NASH)…”
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OGP: A Repository of Experimentally Characterized O-glycoproteins to Facilitate Studies on O-glycosylation by Huang, Jiangming, Wu, Mengxi, Zhang, Yang, Kong, Siyuan, Liu, Mingqi, Jiang, Biyun, Yang, Pengyuan, Cao, Weiqian

“…Numerous studies on cancers, biopharmaceuticals, and clinical trials have necessitated comprehensive and precise analysis of protein O-glycosylation. However,…”
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Distinct enhancer-promoter modes determine Sox2 regulation in mouse pluripotent cells by Huang, Lei, Zhu, Xiusheng, Li, Qing, Kong, Dashuai, Huang, Qitong, Luo, Jing, Kong, Siyuan, Peng, Yanling, Zhang, Yubo

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Interpretation of the Yak Skin Single-Cell Transcriptome Landscape by Zheng, Qingbo, Ye, Na, Bao, Pengjia, Wang, Tong, Ma, Chaofan, Chu, Min, Wu, Xiaoyun, Kong, Siyuan, Guo, Xian, Liang, Chunnian, Pan, Heping, Yan, Ping

“…The morphogenesis of hair follicle structure is accompanied by the differentiation of skin tissue. Mammalian coats are produced by hair follicles. The…”
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Nujiangexanthone A Inhibits Hepatocellular Carcinoma Metastasis via Down Regulation of Cofilin 1 by Zhang, Li, Chai, Zongtao, Kong, Siyuan, Feng, Jiling, Wu, Man, Tan, Jiaqi, Yuan, Man, Chen, Gan, Li, Zhuo, Zhou, Hua, Cheng, Shuqun, Xu, Hongxi

“…Hepatocellular carcinoma (HCC) is one of the malignant tumors with poor prognosis. High expression level of cofilin 1 (CFL1) has been found in many types of…”
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Kill two birds with one stone: making multi-transgenic pre-diabetes mouse models through insulin resistance and pancreatic apoptosis pathogenesis by Kong, Siyuan, Ruan, Jinxue, Zhang, Kaiyi, Hu, Bingjun, Cheng, Yuzhu, Zhang, Yubo, Yang, Shulin, Li, Kui

“…Type 2 diabetes is characterized by insulin resistance accompanied by defective insulin secretion. Transgenic mouse models play an important role in medical…”
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Extracts of Coreopsis tinctoria Nutt. Flower Exhibit Antidiabetic Effects via the Inhibition of α-Glucosidase Activity by Huang, Cheng, Tan, Hongsheng, Kong, Siyuan, Feng, Li, Zhang, Yu, Yu, Lijing, Cai, Wujie, Xu, Hong-Xi

“…The aim of this study was to assay the effects of Coreopsis tinctoria Nutt. flower extracts on hyperglycemia of diet-induced obese mice and the underlying…”
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Deciphering Hi-C: from 3D genome to function by Kong, Siyuan, Zhang, Yubo

“…Hi-C is a commonly used technology in 3D genomics which can depict global chromatin interactions across eukaryotic genome. Integrating with different datasets,…”
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Recent Advances in Software Tools for More Generic and Precise Intact Glycopeptide Analysis by Cao, Weiqian, Liu, Mingqi, Kong, Siyuan, Wu, Mengxi, Zhang, Yang, Yang, Pengyuan

“…Intact glycopeptide identification has long been known as a key and challenging barrier to the comprehensive and accurate understanding the role of…”
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Multi-Objective Dynamic Induction Research of Ship Routes in the Context of Low Carbon Shipping by Zhang, He, Dong, Junfeng, Kong, Siyuan

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Effective Enrichment Strategy Using Boronic Acid-Functionalized Mesoporous Graphene–Silica Composites for Intact N- and O‑Linked Glycopeptide Analysis in Human Serum by Kong, Siyuan, Zhang, Quanqing, Yang, Lujie, Huang, Yuanyu, Liu, Mingqi, Yan, Guoquan, Zhao, Huanhuan, Wu, Mengxi, Zhang, Xiangmin, Yang, Pengyuan, Cao, Weiqian

“…The heterogeneity and low abundance of protein glycosylation present challenging barriers to the analysis of intact glycopeptides, which is key to…”
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