Search Results - "Kong, Qingzhong"

Amyloid fibrils from the N-terminal prion protein fragment are infectious by Choi, Jin-Kyu, Cali, Ignazio, Surewicz, Krystyna, Kong, Qingzhong, Gambetti, Pierluigi, Surewicz, Witold K.

“…Recombinant C-terminally truncated prion protein PrP23-144 (which corresponds to the Y145Stop PrP variant associated with a Gerstmann–Sträussler–Scheinker-like…”
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Early preclinical detection of prions in the skin of prion-infected animals by Wang, Zerui, Manca, Matteo, Foutz, Aaron, Camacho, Manuel V., Raymond, Gregory J., Race, Brent, Orru, Christina D., Yuan, Jue, Shen, Pingping, Li, Baiya, Lang, Yue, Dang, Johnny, Adornato, Alise, Williams, Katie, Maurer, Nicholas R., Gambetti, Pierluigi, Xu, Bin, Surewicz, Witold, Petersen, Robert B., Dong, Xiaoping, Appleby, Brian S., Caughey, Byron, Cui, Li, Kong, Qingzhong, Zou, Wen-Quan

“…A definitive pre-mortem diagnosis of prion disease depends on brain biopsy for prion detection currently and no validated alternative preclinical diagnostic…”
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Novel Strain of the Chronic Wasting Disease Agent Isolated From Experimentally Inoculated Elk With LL132 Prion Protein by Moore, Jo, Tatum, Trudy, Hwang, Soyoun, Vrentas, Catherine, West Greenlee, M. Heather, Kong, Qingzhong, Nicholson, Eric, Greenlee, Justin

“…Chronic wasting disease (CWD) is a fatal, progressive disease that affects cervid species, including Rocky mountain elk ( Cervus elaphus nelsoni ). There are 2…”
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Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors by Kim, Jae-Il, Cali, Ignazio, Surewicz, Krystyna, Kong, Qingzhong, Raymond, Gregory J., Atarashi, Ryuichiro, Race, Brent, Qing, Liuting, Gambetti, Pierluigi, Caughey, Byron, Surewicz, Witold K.

“…Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative diseases that are associated with the conformational conversion of a normal…”
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Artificial strain of human prions created in vitro by Kim, Chae, Xiao, Xiangzhu, Chen, Shugui, Haldiman, Tracy, Smirnovas, Vitautas, Kofskey, Diane, Warren, Miriam, Surewicz, Krystyna, Maurer, Nicholas R., Kong, Qingzhong, Surewicz, Witold, Safar, Jiri G.

“…The molecular mechanism that determines under physiological conditions transmissibility of the most common human prion disease, sporadic Creutzfeldt-Jakob…”
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Decrease in Skin Prion-Seeding Activity of Prion-Infected Mice Treated with a Compound Against Human and Animal Prions: a First Possible Biomarker for Prion Therapeutics by Ding, Mingxuan, Teruya, Kenta, Zhang, Weiguanliu, Lee, Hae Weon, Yuan, Jue, Oguma, Ayumi, Foutz, Aaron, Camacho, Manuel V., Mitchell, Marcus, Greenlee, Justin J., Kong, Qingzhong, Doh-ura, Katsumi, Cui, Li, Zou, Wen-Quan

“…Previous studies have revealed that the infectious scrapie isoform of prion protein (PrP Sc ) harbored in the skin tissue of patients or animals with prion…”
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Variably protease-sensitive prionopathy: A new sporadic disease of the prion protein by Zou, Wen-Quan, Puoti, Gianfranco, Xiao, Xiangzhu, Yuan, Jue, Qing, Liuting, Cali, Ignazio, Shimoji, Miyuki, Langeveld, Jan P.M., Castellani, Rudy, Notari, Silvio, Crain, Barbara, Schmidt, Robert E., Geschwind, Michael, DeArmond, Stephen J., Cairns, Nigel J., Dickson, Dennis, Honig, Lawrence, Torres, Juan Maria, Mastrianni, James, Capellari, Sabina, Giaccone, Giorgio, Belay, Ermias D., Schonberger, Lawrence B., Cohen, Mark, Perry, George, Kong, Qingzhong, Parchi, Piero, Tagliavini, Fabrizio, Gambetti, Pierluigi

“…Objective: The objective of the study is to report 2 new genotypic forms of protease‐sensitive prionopathy (PSPr), a novel prion disease described in 2008, in…”
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Molecular biology and pathology of prion strains in sporadic human prion diseases by Gambetti, Pierluigi, Cali, Ignazio, Notari, Silvio, Kong, Qingzhong, Zou, Wen-Quan, Surewicz, Witold K.

“…Prion diseases are believed to propagate by the mechanism involving self-perpetuating conformational conversion of the normal form of the prion protein, PrP C…”
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An Ex Vivo Brain Slice Culture Model of Chronic Wasting Disease: Implications for Disease Pathogenesis and Therapeutic Development by Kondru, Naveen, Manne, Sireesha, Kokemuller, Robyn, Greenlee, Justin, Greenlee, M. Heather West, Nichols, Tracy, Kong, Qingzhong, Anantharam, Vellareddy, Kanthasamy, Arthi, Halbur, Patrick, Kanthasamy, Anumantha G.

“…Chronic wasting disease (CWD) is a rapidly spreading prion disease of cervids, yet antemortem diagnosis, treatment, and control remain elusive. We recently…”
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A novel human disease with abnormal prion protein sensitive to protease by Gambetti, Pierluigi, Dong, Zhiqian, Yuan, Jue, Xiao, Xiangzhu, Zheng, Mengjie, Alshekhlee, Amer, Castellani, Rudy, Cohen, Mark, Barria, Marcelo A., Gonzalez-Romero, D., Belay, Ermias D., Schonberger, Lawrence B., Marder, Karen, Harris, Carrie, Burke, James R., Montine, Thomas, Wisniewski, Thomas, Dickson, Dennis W., Soto, Claudio, Hulette, Christine M., Mastrianni, James A., Kong, Qingzhong, Zou, Wen-Quan

“…Objective To report a novel prion disease characterized by distinct histopathological and immunostaining features, and associated with an abnormal isoform of…”
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Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy by Otero, Alicia, Barrio, Tomás, Eraña, Hasier, Charco, Jorge M, Betancor, Marina, Díaz-Domínguez, Carlos M, Marín, Belén, Andréoletti, Olivier, Torres, Juan M, Kong, Qingzhong, Badiola, Juan J, Bolea, Rosa, Castilla, Joaquín

“…The role of the glycosylation status of PrP C in the conversion to its pathological counterpart and on cross-species transmission of prion strains has been…”
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Generation of human chronic wasting disease in transgenic mice by Wang, Zerui, Qin, Kefeng, Camacho, Manuel V, Cali, Ignazio, Yuan, Jue, Shen, Pingping, Greenlee, Justin, Kong, Qingzhong, Mastrianni, James A, Zou, Wen-Quan

“…Chronic wasting disease (CWD) is a cervid prion disease caused by the accumulation of an infectious misfolded conformer (PrP ) of cellular prion protein (PrP…”
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Transmission characteristics of variably protease-sensitive prionopathy by Notari, Silvio, Xiao, Xiangzhu, Espinosa, Juan Carlos, Cohen, Yvonne, Qing, Liuting, Aguilar-Calvo, Patricia, Kofskey, Diane, Cali, Ignazio, Cracco, Laura, Kong, Qingzhong, Torres, Juan Maria, Zou, Wenquan, Gambetti, Pierluigi

“…Variably protease-sensitive prionopathy (VPSPr), a recently identified and seemingly sporadic human prion disease, is distinct from Creutzfeldt-Jakob disease…”
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Characterization of Anchorless Human PrP With Q227X Stop Mutation Linked to Gerstmann-Sträussler-Scheinker Syndrome In Vivo and In Vitro by Shen, Pingping, Dang, Johnny, Wang, Zerui, Zhang, Weiguanliu, Yuan, Jue, Lang, Yue, Ding, Mingxuan, Mitchell, Marcus, Kong, Qingzhong, Feng, Jiachun, Rozemuller, Annemiek J. M., Cui, Li, Petersen, Robert B., Zou, Wen-Quan

“…Alteration in cellular prion protein (PrP C ) localization on the cell surface through mediation of the glycosylphosphatidylinositol (GPI) anchor has been…”
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A minimally invasive biomarker for sensitive and accurate diagnosis of Parkinson's disease by Wang, Zerui, Gilliland, Tricia, Kim, Hyun Jo, Gerasimenko, Maria, Sajewski, Kailey, Camacho, Manuel V, Bebek, Gurkan, Chen, Shu G, Gunzler, Steven A, Kong, Qingzhong

“…Seeding activities of disease-associated α-synuclein aggregates (αSyn ), a hallmark of Parkinson's disease (PD), are detectable by seed amplification assay…”
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Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport by Singh, Ajay, Kong, Qingzhong, Luo, Xiu, Petersen, Robert B, Meyerson, Howard, Singh, Neena

“…Despite overwhelming evidence implicating the prion protein (PrP) in prion disease pathogenesis, the normal function of this cell surface glycoprotein remains…”
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Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains by Singh, Ajay, Qing, Liuting, Kong, Qingzhong, Singh, Neena

“…Abstract Prion disease associated neurotoxicity is mainly attributed to PrP-scrapie (PrPSc ), the disease associated isoform of a normal protein, the prion…”
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Publisher Correction: Early preclinical detection of prions in the skin of prion-infected animals by Wang, Zerui, Manca, Matteo, Foutz, Aaron, Camacho, Manuel V., Raymond, Gregory J., Race, Brent, Orru, Christina D., Yuan, Jue, Shen, Pingping, Li, Baiya, Lang, Yue, Dang, Johnny, Adornato, Alise, Williams, Katie, Maurer, Nicholas R., Gambetti, Pierluigi, Xu, Bin, Surewicz, Witold, Petersen, Robert B., Dong, Xiaoping, Appleby, Brian S., Caughey, Byron, Cui, Li, Kong, Qingzhong, Zou, Wen-Quan

“…The original version of this Article contained errors in the author affiliations. Affiliation 2 incorrectly read ‘Department of Neurology, The First Hospital…”
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Small Protease Sensitive Oligomers of PrPSc in Distinct Human Prions Determine Conversion Rate of PrPC by Kim, Chae, Haldiman, Tracy, Surewicz, Krystyna, Cohen, Yvonne, Chen, Wei, Blevins, Janis, Sy, Man-Sun, Cohen, Mark, Kong, Qingzhong, Telling, Glenn C., Surewicz, Witold K., Safar, Jiri G.

“…The mammalian prions replicate by converting cellular prion protein (PrPC) into pathogenic conformational isoform (PrPSc). Variations in prions, which cause…”
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Evaluation of the Human Transmission Risk of an Atypical Bovine Spongiform Encephalopathy Prion Strain by QINGZHONG KONG, MENGJIE ZHENG, MARTUCCI, Francesca, IULINI, Barbara, ACUTIS, Pierluigi, LAN WANG, JINGJING LIANG, MEILING WANG, XINYI LI, MONACO, Salvatore, ZANUSSO, Gianluigi, ZOU, Wen-Quan, CASALONE, Cristina, CARAMELLI, Maria, GAMBETTI, Pierluigi, LIUTING QING, SHENGHAI HUANG, CHAKRABORTY, Bikram, PING WANG, FUSONG CHEN, CALI, Ignazio, CORONA, Cristiano

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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