Search Results - "Kong, John Y"

Integration of a Multichannel Pulsed-Valve Inlet System to a Linear Quadrupole Ion Trap Mass Spectrometer for the Rapid Consecutive Introduction of Nine Reagents for Diagnostic Ion/Molecule Reactions by Kong, John Y, Hilger, Ryan T, Jin, Chunfen, Yerabolu, Ravikiran, Zimmerman, James R, Replogle, Randall W, Jarrell, Tiffany M, Easterling, Leah, Kumar, Rashmi, Kenttämaa, Hilkka I

“…Gas-phase ion/molecule reactions have been used extensively for the structural elucidation of organic compounds in tandem mass spectrometry. Reagents for…”
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Differentiating Isomeric Deprotonated Glucuronide Drug Metabolites via Ion/Molecule Reactions in Tandem Mass Spectrometry by Kong, John Y, Yu, Zaikuan, Easton, Mckay W, Niyonsaba, Edouard, Ma, Xin, Yerabolu, Ravikiran, Sheng, Huaming, Jarrell, Tiffany M, Zhang, Zhoupeng, Ghosh, Arun K, Kenttämaa, Hilkka I

“…Isomeric O- and N-glucuronides are common drug metabolites produced in phase II of drug metabolism. Distinguishing these isomers by using common analytical…”
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Identification of Carboxylate, Phosphate, and Phenoxide Functionalities in Deprotonated Molecules Related to Drug Metabolites via Ion–Molecule Reactions with water and Diethylhydroxyborane by Zhu, Hanyu, Ma, Xin, Kong, John Y., Zhang, Minli, Kenttämaa, Hilkka I.

“…Tandem mass spectrometry based on ion–molecule reactions has emerged as a powerful tool for structural elucidation of ionized analytes. However, most currently…”
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Identification of Protonated Primary Carbamates by Using Gas-Phase Ion–Molecule Reactions Followed by Collision-Activated Dissociation in Tandem Mass Spectrometry Experiments by Niyonsaba, Edouard, Easton, Mckay W, Liu, Judy K.Y, Yu, Zaikuan, Sheng, Huaming, Kong, John Y, Zhang, Zhoupeng, Easterling, Leah F, Milton, Jacob, Kenttämaa, Hilkka I

“…The levels of potentially mutagenic impurities (PMIs) in active pharmaceutical ingredients are highly regulated and must be below a critical safety threshold…”
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Gas-phase ion-molecule reactions for the identification of the sulfone functionality in protonated analytes in a linear quadrupole ion trap mass spectrometer by Tang, Weijuan, Sheng, Huaming, Kong, John Y., Yerabolu, Ravikiran, Zhu, Hanyu, Max, Joann, Zhang, Minli, Kenttämaa, Hilkka I.

“…Rationale The oxidation of sulfur atoms is an important biotransformation pathway for many sulfur‐containing drugs. In order to rapidly identify the sulfone…”
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Mass spectrometric identification of the N-monosubstituted N-hydroxylamino functionality in protonated analytes via ion/molecule reactions in tandem mass spectrometry by Sheng, Huaming, Tang, Weijuan, Yerabolu, Ravikiran, Kong, John Y., Williams, Peggy E., Zhang, Minli, Kenttämaa, Hilkka I.

“…Rationale N‐Monosubstituted hydroxylamines correspond to an important class of metabolites for many bioactive molecules. In this study, a tandem mass…”
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Gas-phase ion-molecule reactions for the identification of the sulfone functionality in protonated analytes in a linear quadrupole ion trap mass spectrometer: Identification of the sulfone functionality by Tang, Weijuan, Sheng, Huaming, Kong, John Y., Yerabolu, Ravikiran, Zhu, Hanyu, Max, Joann, Zhang, Minli, Kenttämaa, Hilkka I.

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