Search Results - "Kong, Hyeon‑Joon"

Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer by Kwon, Ok-Seon, Lee, Haeseung, Kong, Hyeon-Joon, Kwon, Eun-Ji, Park, Ji Eun, Lee, Wooin, Kang, Seungmin, Kim, Mirang, Kim, Wankyu, Cha, Hyuk-Jin

“…Despite the continual discovery of promising new cancer targets, drug discovery is often hampered by the poor druggability of these targets. As such,…”
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Crosstalk between YAP and TGFβ regulates SERPINE1 expression in mesenchymal lung cancer cells by Kong, Hyeon‑Joon, Kwon, Eun‑Ji, Kwon, Ok‑Seon, Lee, Haeseung, Choi, Jeong‑Yun, Kim, Yung‑Jeong, Kim, Wankyu, Cha, Hyuk‑Jin

“…Serpin family E member 1 (SERPINE1), a serine proteinase inhibitor, serves as an important regulator of extra-cellular matrix remodeling. Emerging evidence…”
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TGFβ promotes YAP‐dependent AXL induction in mesenchymal‐type lung cancer cells by Choi, Jeong‐Yun, Lee, Haeseung, Kwon, Eun‐Ji, Kong, Hyeon‐Joon, Kwon, Ok‐Seon, Cha, Hyuk‐Jin

“…Through integration of multiple large database, two oncogenic signatures (YAP conserved and TGFβ‐up signatures) were commonly upregulated in the cancer cell…”
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Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis by Kwon, Ok-Seon, Kwon, Eun-Ji, Kong, Hyeon-Joon, Choi, Jeong-Yoon, Kim, Yun-Jeong, Lee, Eun-Woo, Kim, Wankyu, Lee, Haeseung, Cha, Hyuk-Jin

“…Erastin, a synthetic lethal compound against cancer expressing an oncogenic RAS, inhibits cystine/glutamate antiporters and causes ferroptosis. However,…”
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Screening of cytotoxic or cytostatic flavonoids with quantitative Fluorescent Ubiquitination-based Cell Cycle Indicator-based cell cycle assay by Go, Young-Hyun, Lee, Hyo-Ju, Kong, Hyeon-Joon, Jeong, Ho-Chang, Lee, Dong Young, Hong, Soon-Ki, Sung, Sang Hyun, Kwon, Ok-Seon, Cha, Hyuk-Jin

“…The Fluorescent Ubiquitination-based Cell Cycle Indicator (FUCCI) system can be used not only to study gene expression at a specific cell cycle stage, but also…”
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Correction to: Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer by Kwon, Ok-Seon, Lee, Haeseung, Kong, Hyeon-Joon, Kwon, Eun-Ji, Park, Ji Eun, Lee, Wooin, Kang, Seungmin, Kim, Mirang, Kim, Wankyu, Cha, Hyuk-Jin

“…A Correction to this paper has been published: https://doi.org/10.1038/s41388-021-01642-7…”
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Crosstalk between YAP and TGF[beta] regulates SERPINE1 expression in mesenchymal lung cancer cells by Kong, Hyeon-Joon, Kwon, Eun-Ji, Kwon, Ok-Seon, Lee, Haeseung, Choi, Jeong-Yun, Kim, Yung-Jeong, Kim, Wankyu, Cha, Hyuk-Jin

“…Serpin family E member 1 (SERPINE1), a serine proteinase inhibitor, serves as an important regulator of extracellular matrix remodeling. Emerging evidence…”
Get full text