Search Results - "Kondratyuk, Tamara P"

Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites by Hoshino, Juma, Park, Eun-Jung, Kondratyuk, Tamara P, Marler, Laura, Pezzuto, John M, van Breemen, Richard B, Mo, Shunyan, Li, Yongchao, Cushman, Mark

“…Five resveratrol sulfate metabolites were synthesized and assessed for activities known to be mediated by resveratrol: inhibition of tumor necrosis factor…”
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Ferrocene incorporated selenoureas as anticancer agents by Hussain, Raja Azadar, Badshah, Amin, Pezzuto, John M., Ahmed, Nadeem, Kondratyuk, Tamara P., Park, Eun-Jung

“…[Display omitted] •Seventeen new ferrocene incorporated selenoureas (FIS) have been synthesized.•FIS have been characterized with FTIR, NMR, CHNS, and AAS.•DNA…”
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Potential anti-inflammatory, antioxidant and antimicrobial activities of Sambucus australis by Benevides Bahiense, Jhéssica, Marques, Franciane Martins, Figueira, Mariana Moreira, Vargas, Thais Souza, Kondratyuk, Tamara P., Endringer, Denise Coutinho, Scherer, Rodrigo, Fronza, Marcio

“…Context: Sambucus australis Cham. & Schltdl. (Adoxaceae) is used in Brazilian folk medicine to treat inflammatory disorders. Objective: To evaluate the in…”
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Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents by Kondratyuk, Tamara P, Park, Eun-Jung, Yu, Rui, van Breemen, Richard B, Asolkar, Ratnakar N, Murphy, Brian T, Fenical, William, Pezzuto, John M

“…Two new (1 and 2) and one known phenazine derivative (lavanducyanin, 3) were isolated and identified from the fermentation broth of a marine-derived…”
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Biologically Active Withanolides from Withania coagulans by Ihsan-ul-Haq, Youn, Ui Joung, Chai, Xingyun, Park, Eun-Jung, Kondratyuk, Tamara P, Simmons, Charles J, Borris, Robert P, Mirza, Bushra, Pezzuto, John M, Chang, Leng Chee

“…Bioassay-directed isolation and purification of the crude extract of Withania coagulans, using two assays for cancer chemopreventive mechanisms, led to the…”
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Activity Enhancement of the Synthetic Syrbactin Proteasome Inhibitor Hybrid and Biological Evaluation in Tumor Cells by Archer, Crystal R, Groll, Michael, Stein, Martin L, Schellenberg, Barbara, Clerc, Jérôme, Kaiser, Markus, Kondratyuk, Tamara P, Pezzuto, John M, Dudler, Robert, Bachmann, André S

“…Syrbactins belong to a recently emergent class of bacterial natural product inhibitors that irreversibly inhibit the proteasome of eukaryotes by a novel…”
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Selective Inhibition of Aromatase by a Dihydroisocoumarin from Xyris pterygoblephara by Endringer, Denise C, Guimarães, Keller G, Kondratyuk, Tamara P, Pezzuto, John M, Braga, Fernão C

“…Aromatase is a well-established target for the chemoprevention of breast cancer. The dihydroisocoumarin…”
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Suppression of tumor necrosis factor-α-induced nuclear factor κB activation and aromatase activity by capsaicin and its analog capsazepine by Luqman, Suaib, Meena, Abha, Marler, Laura E, Kondratyuk, Tamara P, Pezzuto, John M

“…Target-specific drugs, including natural products, offer promise for the amelioration of cancer and other human ailments. Capsaicin, the pungent ingredient…”
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Resveratrol analogs: promising chemopreventive agents by Ogas, Talysa, Kondratyuk, Tamara P., Pezzuto, John M.

“…Although resveratrol can modulate multiple stages of carcinogenesis, by most common standards it is not a good drug candidate. Resveratrol lacks potency, high…”
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Wound healing activity of terpinolene and α-phellandrene by attenuating inflammation and oxidative stress in vitro by de Christo Scherer, Marcella Malavazi, Marques, Franciane Martins, Figueira, Mariana Moreira, Peisino, Maria Carolina Oliveira, Schmitt, Elisângela Flávia Pimentel, Kondratyuk, Tamara P., Endringer, Denise Coutinho, Scherer, Rodrigo, Fronza, Marcio

“…This study was undertaken to investigate the in vitro wound healing effects and the anti-inflammatory and antioxidant activities of terpinolene and…”
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NF-κB Inhibitory and Antibacterial Helvolic and Fumagillin Derivatives from Aspergillus terreus by Zaman, KH Ahammad Uz, Hu, Zhenquan, Wu, Xiaohua, Hou, Shaobin, Saito, Jennifer, Kondratyuk, Tamara P, Pezzuto, John M, Cao, Shugeng

“…Two new helvolic acid analogues (1 and 2) and one new fumagillin derivative containing an octahydroisobenzofuran moiety (3), together with four known compounds…”
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Chemical profile of mango (Mangifera indica L.) using electrospray ionisation mass spectrometry (ESI-MS) by Oliveira, Bruno G., Costa, Helber B., Ventura, José A., Kondratyuk, Tamara P., Barroso, Maria E.S., Correia, Radigya M., Pimentel, Elisângela F., Pinto, Fernanda E., Endringer, Denise C., Romão, Wanderson

“…•The chemical profile of mango at four maturation stages was determined using ESI-MS.•Primary and secondary metabolites were identified at the third maturation…”
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Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1 by Prior, Allan M., Yu, Xufen, Park, Eun-Jung, Kondratyuk, Tamara P., Lin, Yan, Pezzuto, John M., Sun, Dianqing

“…[Display omitted] In our ongoing effort of discovering anticancer and chemopreventive agents, a series of 2-arylindole derivatives were synthesized and…”
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Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets by Mayhoub, Abdelrahman S., Marler, Laura, Kondratyuk, Tamara P., Park, Eun-Jung, Pezzuto, John M., Cushman, Mark

“…Chemoprevention is an approach to decrease cancer morbidity and mortality through inhibition of carcinogenesis and prevention of disease progression. Although…”
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A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells by Chelsky, Zachary L, Yue, Peibin, Kondratyuk, Tamara P, Paladino, David, Pezzuto, John M, Cushman, Mark, Turkson, James

“…(E)-4-(3,5-dimethoxystyryl)phenyl acetate (Cmpd1) is a resveratrol analog that preferentially inhibits glioma, breast, and pancreatic cancer cell growth, with…”
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Inhibition of Lipopolysaccharide-Induced Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Expression by 4-[(2′-O-acetyl-α-L-Rhamnosyloxy)Benzyl]Isothiocyanate from Moringa oleifera by Park, Eun-Jung, Cheenpracha, Sarot, Chang, Leng Chee, Kondratyuk, Tamara P, Pezzuto, John M

“…Moringa oleifera Lamarck is commonly consumed for nutritional or medicinal properties. We recently reported the isolation and structure elucidation of novel…”
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Synthesis and Structure-Activity Relationships of Tetrahydro-β-carboline Derivatives as Anticancer and Cancer-chemopreventive Agents by Zhang, Mingming, Park, Eun-Jung, Kondratyuk, Tamara P, Pezzuto, John M, Sun, Dianqing

“…There is an unmet clinical need to develop new anticancer and chemopreventive agents. The aim of the present study was to identify β-carboline derivatives with…”
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Phytochemical profile of genotypes of Euterpe edulis Martius – Juçara palm fruits by Barroso, Maria E.S., Oliveira, Bruno G., Pimentel, Elisângela F., Pereira, Pedro M., Ruas, Fabiana G., Andrade, Tadeu U., Lenz, Dominik, Scherer, Rodrigo, Fronza, Marcio, Ventura, José A., Vaz, Boniek G., Kondratyuk, Tamara P., Romão, Wanderson, Endringer, Denise C.

“…Juçara fruit (Euterpe edulis) has received attention due to its similarities to Euterpe oleracea (Açaí). The aim of this study was to evaluate the…”
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In vitro anti-inflammatory activity of terpenes via suppression of superoxide and nitric oxide generation and the NF-κB signalling pathway by Marques, Franciane Martins, Figueira, Mariana Moreira, Schmitt, Elisângela Flávia Pimentel, Kondratyuk, Tamara P., Endringer, Denise Coutinho, Scherer, Rodrigo, Fronza, Marcio

“…Background and Aims Terpenes are considered the main components of essential oils and an important source for the identification of novel lead molecules. This…”
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Investigation of Chemopreventive and Antiproliferative Potential of Dicliptera roxburghiana by Ahmad, Bushra, Khan, Muhammad Rashid, Shah, Naseer Ali, Kondratyuk, Tamara P., Ahmed, Nadeem, Pezzuto, John M., Gul, Asma, Khattak, Aishma

“…Context: Carcinogenesis causes much human misery. It is a process involving multistage alterations. Medicinal plants are candidates for beneficial anticancer…”
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