Search Results - "Kondratyuk, Tamara"
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Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites
Published in Journal of medicinal chemistry (08-07-2010)“…Five resveratrol sulfate metabolites were synthesized and assessed for activities known to be mediated by resveratrol: inhibition of tumor necrosis factor…”
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Resveratrol analogs: promising chemopreventive agents
Published in Annals of the New York Academy of Sciences (01-07-2013)“…Although resveratrol can modulate multiple stages of carcinogenesis, by most common standards it is not a good drug candidate. Resveratrol lacks potency, high…”
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3
Wound healing activity of terpinolene and α-phellandrene by attenuating inflammation and oxidative stress in vitro
Published in Journal of tissue viability (01-05-2019)“…This study was undertaken to investigate the in vitro wound healing effects and the anti-inflammatory and antioxidant activities of terpinolene and…”
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4
NF-κB Inhibitory and Antibacterial Helvolic and Fumagillin Derivatives from Aspergillus terreus
Published in Journal of natural products (Washington, D.C.) (27-03-2020)“…Two new helvolic acid analogues (1 and 2) and one new fumagillin derivative containing an octahydroisobenzofuran moiety (3), together with four known compounds…”
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5
Chemical profile of mango (Mangifera indica L.) using electrospray ionisation mass spectrometry (ESI-MS)
Published in Food chemistry (01-08-2016)“…•The chemical profile of mango at four maturation stages was determined using ESI-MS.•Primary and secondary metabolites were identified at the third maturation…”
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Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1
Published in Bioorganic & medicinal chemistry letters (15-12-2017)“…[Display omitted] In our ongoing effort of discovering anticancer and chemopreventive agents, a series of 2-arylindole derivatives were synthesized and…”
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Ferrocene incorporated selenoureas as anticancer agents
Published in Journal of photochemistry and photobiology. B, Biology (01-07-2015)“…[Display omitted] •Seventeen new ferrocene incorporated selenoureas (FIS) have been synthesized.•FIS have been characterized with FTIR, NMR, CHNS, and AAS.•DNA…”
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Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets
Published in Bioorganic & medicinal chemistry (01-01-2012)“…Chemoprevention is an approach to decrease cancer morbidity and mortality through inhibition of carcinogenesis and prevention of disease progression. Although…”
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Potential anti-inflammatory, antioxidant and antimicrobial activities of Sambucus australis
Published in Pharmaceutical biology (01-01-2017)“…Context: Sambucus australis Cham. & Schltdl. (Adoxaceae) is used in Brazilian folk medicine to treat inflammatory disorders. Objective: To evaluate the in…”
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A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells
Published in Molecular pharmacology (01-09-2015)“…(E)-4-(3,5-dimethoxystyryl)phenyl acetate (Cmpd1) is a resveratrol analog that preferentially inhibits glioma, breast, and pancreatic cancer cell growth, with…”
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Inhibition of Lipopolysaccharide-Induced Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Expression by 4-[(2′-O-acetyl-α-L-Rhamnosyloxy)Benzyl]Isothiocyanate from Moringa oleifera
Published in Nutrition and cancer (01-08-2011)“…Moringa oleifera Lamarck is commonly consumed for nutritional or medicinal properties. We recently reported the isolation and structure elucidation of novel…”
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Synthesis and Structure-Activity Relationships of Tetrahydro-β-carboline Derivatives as Anticancer and Cancer-chemopreventive Agents
Published in Anticancer research (01-08-2018)“…There is an unmet clinical need to develop new anticancer and chemopreventive agents. The aim of the present study was to identify β-carboline derivatives with…”
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Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents
Published in Marine drugs (01-02-2012)“…Two new (1 and 2) and one known phenazine derivative (lavanducyanin, 3) were isolated and identified from the fermentation broth of a marine-derived…”
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Phytochemical profile of genotypes of Euterpe edulis Martius – Juçara palm fruits
Published in Food research international (01-02-2019)“…Juçara fruit (Euterpe edulis) has received attention due to its similarities to Euterpe oleracea (Açaí). The aim of this study was to evaluate the…”
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In vitro anti-inflammatory activity of terpenes via suppression of superoxide and nitric oxide generation and the NF-κB signalling pathway
Published in Inflammopharmacology (01-04-2019)“…Background and Aims Terpenes are considered the main components of essential oils and an important source for the identification of novel lead molecules. This…”
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Investigation of Chemopreventive and Antiproliferative Potential of Dicliptera roxburghiana
Published in Integrative cancer therapies (01-01-2022)“…Context: Carcinogenesis causes much human misery. It is a process involving multistage alterations. Medicinal plants are candidates for beneficial anticancer…”
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NF-κB inhibitors, unique γ-pyranol-γ-lactams with sulfide and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462
Published in Scientific reports (05-09-2017)“…LC-UV/MS-based metabolomic analysis of the Hawaiian endophytic fungus Paraphaeosphaeria neglecta FT462 led to the identification of four unique…”
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Anti-inflammatory and Quinone Reductase Inducing Compounds from Fermented Noni (Morinda citrifolia) Juice Exudates
Published in Journal of natural products (Washington, D.C.) (24-06-2016)“…A new fatty acid ester disaccharide, 2-O-(β-d-glucopyranosyl)-1-O-(2E,4Z,7Z)-deca-2,4,7-trienoyl-β-d-glucopyranose (1), a new ascorbic acid derivative,…”
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Withanolides derived from Physalis peruviana (Poha) with potential anti-inflammatory activity
Published in Bioorganic & medicinal chemistry letters (15-06-2016)“…[Display omitted] Three new withanolides, physaperuvin G (1), with physaperuvins I (2), and J (3), along with seven known derivatives (4–10), were isolated…”
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Potential Chemopreventive Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces Species, Strain CNS284
Published in Journal of medicinal chemistry (23-12-2010)“…The isolation of 2-bromo-1-hydroxyphenazine from a marine Streptomyces species, strain CNS284, and its activity against NF-κB, suggested that a short and…”
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