Search Results - "Kondo, Rubii"

Increased TMEM16A-Mediated Ca2+-Activated Cl− Currents in Portal Vein Smooth Muscle Cells of Caveolin 1-Deficient Mice by Kawata, Naoki, Kondo, Rubii, Suzuki, Yoshiaki, Yamamura, Hisao

“…Ca2+-activated Cl− (ClCa) channels regulate membrane excitability and myogenic tone in vascular smooth muscles. TMEM16A-coding proteins are mainly responsible…”
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Ca2+ Signaling and Proliferation via Ca2+-Sensing Receptors in Human Hepatic Stellate LX-2 Cells by Kondo, Rubii, Kawata, Naoki, Suzuki, Yoshiaki, Yamamura, Hisao

“…Hepatic stellate cells (HSCs) play a significant role in the development of chronic liver diseases. Hepatic damage activates HSCs and results in hepatic…”
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Mitofusin 1 and 2 differentially regulate mitochondrial function underlying Ca2+ signaling and proliferation in rat aortic smooth muscle cells by Inagaki, Sou, Suzuki, Yoshiaki, Kawasaki, Keisuke, Kondo, Rubii, Imaizumi, Yuji, Yamamura, Hisao

“…Mitochondria play a substantial role in cytosolic Ca2+ buffering and energy metabolism. We recently demonstrated that mitofusin 2 (Mfn2) regulated Ca2+…”
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Corosolic acid ameliorates vascular remodeling in pulmonary arterial hypertension via the downregulation of STAT3 signaling by Kawade, Akiko, Yamamura, Aya, Kondo, Rubii, Suzuki, Yoshiaki, Yamamura, Hisao

“…Pulmonary arterial hypertension (PAH) is a progressive and fatal disease that is characterized by vascular remodeling of the pulmonary artery. PAH remodeling…”
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SKF96365 activates calcium-sensing receptors in pulmonary arterial smooth muscle cells by Miyaki, Riko, Yamamura, Aya, Kawade, Akiko, Fujiwara, Moe, Kondo, Rubii, Suzuki, Yoshiaki, Yamamura, Hisao

“…In pulmonary arterial smooth muscle cells (PASMCs), an increase in the cytosolic Ca2+ concentration ([Ca2+]cyt) is involved in many physiological processes…”
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Upregulated ClC3 Channels/Transporters Elicit Swelling-Activated Cl− Currents and Induce Excessive Cell Proliferation in Idiopathic Pulmonary Arterial Hypertension by Amano, Taiki, Yamamura, Aya, Fujiwara, Moe, Hirai, Seiji, Kondo, Rubii, Suzuki, Yoshiaki, Yamamura, Hisao

“…Pulmonary arterial hypertension (PAH) is characterized by vascular remodeling of the pulmonary artery, which is mainly attributed to the excessive…”
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Involvement of TREK1 channels in the proliferation of human hepatic stellate LX-2 cells by Kondo, Rubii, Deguchi, Akari, Kawata, Naoki, Suzuki, Yoshiaki, Yamamura, Hisao

“…Activation of hepatic stellate cells (HSCs) causes hepatic fibrosis and results in chronic liver diseases. Although activated HSC functions are facilitated by…”
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Involvement of small-conductance Ca2+-activated K+ (SKCa2) channels in spontaneous Ca2+ oscillations in rat pinealocytes by Ando, Shunsuke, Mizutani, Hiroya, Muramatsu, Makoto, Hagihara, Yumiko, Mishima, Hiroki, Kondo, Rubii, Suzuki, Yoshiaki, Imaizumi, Yuji, Yamamura, Hisao

“…Melatonin secretion from the pineal glands regulates circadian rhythms in mammals. Melatonin production is decreased by an increase in cytosolic Ca2+…”
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Comparative analysis of age in monocrotaline-induced pulmonary hypertensive rats by Kawade, Akiko, Yamamura, Aya, Fujiwara, Moe, Kobayashi, Saki, Mori, Shiho, Horii, Chihiro, Hiraku, Akari, Suzumura, Sayo, Tsukamoto, Kikuo, Ohara, Naoki, Kondo, Rubii, Suzuki, Yoshiaki, Yamamura, Hisao

“…Pulmonary arterial hypertension (PAH) is a rare, progressive, and fatal cardiovascular/lung disease. The incidence rate is affected by age. Monocrotaline (MCT,…”
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Pimaric acid reduces vasoconstriction via BKCa channel activation and VDCC inhibition in rat pulmonary arterial smooth muscles by Ishida, Masashi, Yamamura, Aya, Fujiwara, Moe, Amano, Taiki, Ota, Mina, Hikawa, Yukari, Kondo, Rubii, Suzuki, Yoshiaki, Imaizumi, Yuji, Yamamura, Hisao

“…Pulmonary vessels play a pivotal role in oxygen circulation. We previously demonstrated that pimaric acid (PiMA) activated large-conductance Ca2+-activated K+…”
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Downregulation of Ca2+-Activated Cl− Channel TMEM16A Mediated by Angiotensin II in Cirrhotic Portal Hypertensive Mice by Kondo, Rubii, Furukawa, Nami, Deguchi, Akari, Kawata, Naoki, Suzuki, Yoshiaki, Imaizumi, Yuji, Yamamura, Hisao

“…Portal hypertension is defined as an increased pressure in the portal venous system and occurs as a major complication in chronic liver diseases. The…”
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Up-regulated expression of two-pore domain K + channels, KCNK1 and KCNK2, is involved in the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary arterial hypertension by Shima, Natsumi, Yamamura, Aya, Fujiwara, Moe, Amano, Taiki, Matsumoto, Kazuyuki, Sekine, Taiga, Okano, Haruka, Kondo, Rubii, Suzuki, Yoshiaki, Yamamura, Hisao

“…Pulmonary arterial hypertension (PAH) is a severe and rare disease in the cardiopulmonary system. Its pathogenesis involves vascular remodeling of the…”
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Increased TMEM16A-mediated Ca2+-activated Cl- currents in portal vein smooth muscle cells of caveolin 1-deficient mice by Kawata, Naoki, Kondo, Rubii, Suzuki, Yoshiaki, Yamamura, Hisao

“…Ca2+-activated Cl- (ClCa) channels regulate membrane excitability and myogenic tone in vascular smooth muscles. TMEM16A-coding proteins are mainly responsible…”
Get full text

Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension by Yamamura, Aya, Fujiwara, Moe, Kawade, Akiko, Amano, Taiki, Hossain, Alamgir, Nayeem, Md Junayed, Kondo, Rubii, Suzuki, Yoshiaki, Inoue, Yasumichi, Hayashi, Hidetoshi, Suzuki, Susumu, Sato, Motohiko, Yamamura, Hisao

“…Pulmonary arterial hypertension (PAH) is a progressive and life-threatening disease that is characterized by vascular remodeling of the pulmonary artery…”
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Upregulated ClC3 channels/transporters elicit swelling-activated Cl- currents and induce excessive cell proliferation in idiopathic pulmonary arterial hypertension by Amano, Taiki, Yamamura, Aya, Fujiwara, Moe, Hirai, Seiji, Kondo, Rubii, Suzuki, Yoshiaki, Yamamura, Hisao

“…Pulmonary arterial hypertension (PAH) is characterized by vascular remodeling of the pulmonary artery, which is mainly attributed to the excessive…”
Get full text

Downregulation of Ca 2+ -Activated Cl - Channel TMEM16A Mediated by Angiotensin II in Cirrhotic Portal Hypertensive Mice by Kondo, Rubii, Furukawa, Nami, Deguchi, Akari, Kawata, Naoki, Suzuki, Yoshiaki, Imaizumi, Yuji, Yamamura, Hisao

“…Portal hypertension is defined as an increased pressure in the portal venous system and occurs as a major complication in chronic liver diseases. The…”
Get full text

Ca 2+ Signaling and Proliferation via Ca 2+ -Sensing Receptors in Human Hepatic Stellate LX-2 Cells by Kondo, Rubii, Kawata, Naoki, Suzuki, Yoshiaki, Yamamura, Hisao

“…Hepatic stellate cells (HSCs) play a significant role in the development of chronic liver diseases. Hepatic damage activates HSCs and results in hepatic…”
Get full text

Mitofusin 1 and 2 differentially regulate mitochondrial function underlying Ca 2+ signaling and proliferation in rat aortic smooth muscle cells by Inagaki, Sou, Suzuki, Yoshiaki, Kawasaki, Keisuke, Kondo, Rubii, Imaizumi, Yuji, Yamamura, Hisao

“…Mitochondria play a substantial role in cytosolic Ca buffering and energy metabolism. We recently demonstrated that mitofusin 2 (Mfn2) regulated Ca signaling…”
Get full text

Involvement of small-conductance Ca 2+ -activated K + (SK Ca 2) channels in spontaneous Ca 2+ oscillations in rat pinealocytes by Ando, Shunsuke, Mizutani, Hiroya, Muramatsu, Makoto, Hagihara, Yumiko, Mishima, Hiroki, Kondo, Rubii, Suzuki, Yoshiaki, Imaizumi, Yuji, Yamamura, Hisao

“…Melatonin secretion from the pineal glands regulates circadian rhythms in mammals. Melatonin production is decreased by an increase in cytosolic Ca…”
Get full text