Search Results - "Kondaurova, E M"
-
1
Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like behavior (BTBR) or its absence (С57BL/6 J)
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-07-2024)“…Analysis of the mechanisms underlying autism spectrum disorder (ASD) is an urgent task due to the ever-increasing prevalence of this condition. The study of…”
Get full text
Journal Article -
2
Risk Neurogenes for Long-Term Spaceflight: Dopamine and Serotonin Brain System
Published in Molecular neurobiology (01-06-2015)Get full text
Journal Article -
3
Inhibitor of Striatal-Enriched Protein Tyrosine Phosphatase, 8-(Trifluoromethyl)-1,2,3,4,5-Benzopentathiepin-6-Amine hydrochloride (TC-2153), Produces Antidepressant-Like Effect and Decreases Functional Activity and Protein Level of 5-HT2A Receptor in the Brain
Published in Neuroscience (01-12-2018)“…•TC-2153 administration attenuates 5-HT2A receptor functional activity in the brain.•Chronic TC-2153 administration produces antidepressant-like…”
Get full text
Journal Article -
4
Risk Neurogenes for Long-Term Spaceflight: Dopamine and Serotonin Brain System
Published in Molecular neurobiology (01-06-2015)“…Mice were exposed to 1 month of spaceflight on Russian biosatellite BION-M1 to determine its effect on the expression of key genes in the brain dopamine (DA)…”
Get full text
Journal Article -
5
Inhibitor of Striatal-Enriched Protein Tyrosine Phosphatase, 8-(Trifluoromethyl)-1,2,3,4,5-Benzopentathiepin-6-Amine hydrochloride (TC-2153), Produces Antidepressant-Like Effect and Decreases Functional Activity and Protein Level of 5-HT 2A Receptor in the Brain
Published in Neuroscience (01-12-2018)“…The serotoninergic 5-HT receptor is involved in the mechanism of depression and antidepressant drugs action. Earlier we showed that striatal-enriched protein…”
Get full text
Journal Article -
6
Effect of brain-derived neurotrophic factor on behavior and key members of the brain serotonin system in genetically predisposed to behavioral disorders mouse strains
Published in Neuroscience (12-07-2012)“…Highlights ► Central BDNF administration produced ameliorative effect on depressive-like behavior. ► Long-term BDNF effect on “depressive” ASC mice involves…”
Get full text
Journal Article -
7
Effect of amisulpride on the expression of serotonin receptors, neurotrophic factor BDNF and its receptors in mice with overexpression of the aggregation-prone [R406W] mutant tau protein
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-07-2024)“…Serotonin 5-HT7 receptors (5-HT7R) are attracting increasing attention as important participants in the mechanisms of Alzheimer's disease and as a possible…”
Get full text
Journal Article -
8
Effects of Acute Stress in Mice with 5-HT1A Receptors with Different Sensitivities to Chronic Activation by 8-OH-DPAT
Published in Neuroscience and behavioral physiology (01-05-2021)“…Recombinant mouse strain B6.CBA-D13Mit76C (B6-M76C) and B6.CBA-D13Mit76B (B6-M76B), with 5-HT 1A receptors with different sensitivities to chronic activation…”
Get full text
Journal Article -
9
Alterations in pharmacological and behavioural responses in recombinant mouse line with an increased predisposition to catalepsy: role of the 5‐HT1A receptor
Published in British journal of pharmacology (01-07-2016)“…Background and Purpose One important syndrome of psychiatric disorders in humans is catalepsy. Here, we created mice with different predispositions to…”
Get full text
Journal Article -
10
Effect of actual long-term spaceflight on BDNF, TrkB, p75, BAX and BCL-XL genes expression in mouse brain regions
Published in Neuroscience (22-01-2015)“…Highlights • Actual spaceflight considerably decreased BCL-XL gene expression in the hypothalamus. • Long-term spaceflight significantly increased BCL-XL gene…”
Get full text
Journal Article -
11
Alteration of the brain morphology and the response to the acute stress in the recombinant mouse lines with different predisposition to catalepsy
Published in Neuroscience research (01-04-2017)“…•Catalepsy-prone line of mice in the C57BL/6 genome was bred.•The volume of the total brain was decreased in catalepsy-prone line.•Sizes of the striatum,…”
Get full text
Journal Article -
12
Studies of Catalepsy and Other Forms of Behavior Using Recombinant Mouse Strains
Published in Neuroscience and behavioral physiology (01-11-2016)“…Catalepsy is a passive defensive freezing reaction in response to threatening stimuli. In hypertrophied form it constitutes a symptom of impaired brain…”
Get full text
Journal Article -
13
On the Functional Cross-Talk between Brain 5-HT1A and 5-HT2A Receptors
Published in Zurnal vyss̆ej nervnoj dejatelnosti imeni I P Pavlova (01-03-2015)“…We have found that activation of 5-HT1A receptor with 8-OH-DPAT (0.1, 0.5 and 1.0 mg/kg, i. p.) considerably and dose-dependently reduced the number of 5-HT2A…”
Get more information
Journal Article -
14
Functional Interactions between 5-HT1A and 5-HT2A Receptors in the Brain
Published in Neuroscience and behavioral physiology (01-09-2016)“…Activation of 5-HT 1A receptors by their agonist 5-OH-DPAT (0.1, 0.5. and 1.0 mg/kg, i.p.) produced a significant and dose-dependent decrease in the number of…”
Get full text
Journal Article -
15
Genetic structure of hereditary catalepsy in mice
Published in Genes, brain and behavior (01-06-2008)“…Catalepsy or pronounced freezing is a natural passive defense strategy in animals and a syndrome of some mental disorders in human. Hereditary catalepsy was…”
Get full text
Journal Article -
16
The effects of chronic alcoholization on the expression of brain-derived neurotrophic factor and its receptors in the brains of mice genetically predisposed to depressive-like behavior
Published in Molecular biology (New York) (01-07-2017)“…Brain-derived neurotropic factor (BDNF) plays an important role in mechanisms of depression. Precursor protein of this factor (proBDNF) can initiate apoptosis…”
Get full text
Journal Article -
17
The role of 5‐HT2A receptor and 5‐HT2A/5‐HT1A receptor interaction in the suppression of catalepsy
Published in Genes, brain and behavior (01-07-2010)“…In the present study, the 5‐HT2A and 5‐HT1A receptors functional activity and 5‐HT2A receptor gene expression were examined in the brain of ASC/Icg and…”
Get full text
Journal Article -
18
The Effects of Chronic Alcoholization on the Expression of Brain-Derived Neurotrophic Factor and Its Receptors in the Brains of Mice Genetically Predisposed to Depressive-Like Behavior
Published in Molekuliarnaia biologiia (01-07-2017)“…Brain-derived neurotropic factor (BDNF) plays an important role in mechanisms of depression. Precursor protein of this factor (proBDNF) can initiate apoptosis…”
Get more information
Journal Article -
19
Expression of palmitoyl transferases in brain structures of mice genetically predisposed to depressive-like behavior
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (10-08-2018)“…Most G-coupled receptors undergo posttranslational modifications. Among these modifications is S-palmitoylation, carried out by specialized enzymes palmitoyl…”
Get full text
Journal Article -
20
Selection for the Predisposition to Catalepsy Enhances Depressive-like Traits in Mice
Published in Russian journal of genetics (01-09-2005)“…Immobility reaction or catalepsy is a natural passive defensive (cryptic) behavioral response to the appearance of a predator. Selection for high…”
Get full text
Journal Article