Search Results - "Konczalik, J"

Earfold™: A combined approach with conchal bowl reduction by Kang, Norbert V., Konczalik, Wojciech J., Michno, Dominika A.

“…Prominent ear deformity is common amongst the human population and is partly due to underdevelopment of the antihelical fold, a prominent conchal bowl, or…”
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Background on the system of integral evaluation of human exposure to toxic substances in the work and municipal environments by Dutkiewicz, T, Kończalik, J

“…Exposure to toxic chemicals in the work, natural and home environments is recognised as combined exposure. The system of integral evaluation of human exposure…”
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Effects of a novel sodium channel blocker, GSK2339345, in patients with refractory chronic cough by Smith, Jaclyn A, McGarvey, Lorcan P A, Badri, Huda, Satia, Imran, Warren, Francis, Siederer, Sarah, Liefaard, Lia, Murdoch, Robert D, Povey, Kathryn, Marks-Konczalik, Joanna

“…Voltage-gated sodium channels (VGSC) are important in the initiation and propagation of action potentials in afferent sensory nerve fibers responsible for…”
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A45 FOR YOUR EYES ONLY, BUT EVERYONE WILL HEAR THE CHRONIC COUGH: Safety, Tolerability, Pharmacokinetics (pk) And Pharmacodynamics (pd) Of Gsk2339345 - Novel Sodium Channel Blocker. Results From Two Phase I Studies In Healthy Volunteers by Marks-Konczalik, J, Murdoch, R D, Kelly, K L, Cheesbrough, A, Siederer, S K, Singh, D, Smith, J A

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Cytokine-mediated Transcriptional Induction of the Human Inducible Nitric Oxide Synthase Gene Requires Both Activator Protein 1 and Nuclear Factor κB-binding Sites by Marks-Konczalik, Joanna, Chu, Shan C., Moss, Joel

“…The involvement of AP-1 and NF-κB transcription factors in cytokine-mediated induction of human inducible nitric oxide synthase (hiNOS) promoter activity was…”
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Environmental determinants of selected family-oriented health indicators by Dutkiewicz, T, Kończalik, J, Andryszek, C, Rachański, D

“…Based on the levels of environmental contamination and degradation, synthetic measures of environmental hazards in urban and rural regions in Poland were…”
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IL-2-Induced Activation-Induced Cell Death Is Inhibited in IL-15 Transgenic Mice by Marks-Konczalik, Joanna, Dubois, Sigrid, Losi, Jacqueline M., Sabzevari, Helen, Yamada, Nobuo, Feigenbaum, Lionel, Waldmann, Thomas A., Tagaya, Yutaka

“…A transgenic (Tg) mouse expressing human IL-15 was generated to define the role of IL-15 in the normal immune response. Overexpression of IL-15 resulted in an…”
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Mitogen-activated Protein Kinases Mediate Activator Protein-1-dependent Human Inducible Nitric-oxide Synthase Promoter Activation by Kristof, Arnold S., Marks-Konczalik, Joanna, Moss, Joel

“…Inducible nitric-oxide synthase (iNOS) is an important signaling protein involved in the regulation of biological processes (e.g. vasodilation, inflammation)…”
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Spatial distribution of negative health indices in ecological hazard areas in Poland by Dutkiewicz, T, Kończalik, J, Andryszek, C, Rachański, D

“…Spatial distribution of negative health indices (relative risk, synthetic measure) was demonstrated in 27 ecological hazard areas (EHAs) in Poland. For…”
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Induction of manganese superoxide dismutase gene expression in bronchoepithelial cells after rockwool exposure by Marks-Konczalik, J, Gillissen, A, Jaworska, M, Löseke, S, Voss, B, Fisseler-Eckhoff, A, Schmitz, I, Schultze-Werninghaus, G

“…Superoxide dismutases play an important protective role in the lung defense against the pro-oxidative effect of fibrous dusts (e.g. crocidolite fibers)…”
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Stimulation of Signal Transducer and Activator of Transcription-1 (STAT1)-dependent Gene Transcription by Lipopolysaccharide and Interferon-γ Is Regulated by Mammalian Target of Rapamycin by Kristof, Arnold S., Marks-Konczalik, Joanna, Billings, Eric, Moss, Joel

“…Mammalian target of rapamycin (mTOR) and phosphatidylinositol 3-kinase (PI3K) regulate cell growth, protein synthesis, and apoptosis in response to nutrients…”
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Selected aspects of the population health status in ecological hazard areas in comparison with ecologically "clean" area. II. Assessment of spatial distribution of mortality by Dutkiewicz, T, Andryszek, C, Kończalik, J, Rachański, D

“…On the basis of age adjusted rates of mortality from all diseases and from diseases of the circulatory system in female and male populations living in…”
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Selected aspects of the population health status in ecological hazard areas in comparison with ecologically "clean area". III. localisation of urban regions with high mortality from all and from the circulatory system diseases by Dutkiewicz, T, Konczalik, J, Andryszek, C, Rachanski, D

“…Territorial localisation of urban regions with particularly high mortality from all diseases and from diseases of the circulatory system in males and females…”
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Analysis of the Cytokine-Stimulated Human Inducible Nitric Oxide Synthase (iNOS) Gene: Characterization of Differences between Human and Mouse iNOS Promoters by Chu, Shan C., Marks-Konczalik, Joanna, Wu, Hai-Ping, Banks, Tyrone C., Moss, Joel

“…Expression of human inducible nitric oxide synthase (hiNOS) is under cytokine control and is transcriptionally regulated. The hiNOS and mouse iNOS (miNOS)…”
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Skin absorption and per os administration of methanol in men by Dutkiewicz, B, Kończalik, J, Karwacki, W

“…Methanol absorption rate through the human skin has been examined by the use of modified direct method, and a value of 0.192 mg/cm2/min was determined. The…”
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STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation by Xu, Weiling, Comhair, Suzy A A, Zheng, Shuo, Chu, Shan C, Marks-Konczalik, Joanna, Moss, Joel, Haque, S Jaharul, Erzurum, Serpil C

“…Interferon-gamma (IFN-gamma) is required for induction of the human nitric oxide synthase-2 (NOS2) gene in lung epithelium. Although the human NOS2 promoter…”
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Indicator-Based Assessment of Environmental Hazards and Health Effects in the Industrial Cities of Upper Silesia, Poland by Wcislo, Eleonora, Dutkiewicz, Tadeusz, Konczalik, Jerzy

“…Using an indicator-based approach, we assessed environmental hazards and related health effects in populations of industrial cities with more than 100,000…”
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The impact of the chemical industry on the human environment by Dutkiewicz, T, Rolecki, R, Kończalik, J, Swiatczak, J

“…The magnitude of the emitted to the air dusts and gases, liquid and solid wastes disposal produced by chemical industry is presented. Impact of chemical…”
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Effect of Paraquat Intoxication and Ambroxol Treatment on Hydrogen Peroxide Production and Lipid Peroxidation in Selected Organs of Rat by Piotrowski, Wojciech Jerzy, Pietras, Tadeusz, Kurmanowska, Zofia, Nowak, Dariusz, Marczak, Jerzy, Marks-Kończalik, Joanna, Mazerant, Piotr

“…Paraquat (Pq) is a herbicide which is very toxic to all animals and to man. It generates free radicals and leads to acute or chronic lung injury and usually to…”
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Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites by Marks-Konczalik, J, Chu, S C, Moss, J

“…The involvement of AP-1 and NF-kappaB transcription factors in cytokine-mediated induction of human inducible nitric oxide synthase (hiNOS) promoter activity…”
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