Search Results - "Koncz, Tamas"
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Tofacitinib versus Methotrexate in Rheumatoid Arthritis
Published in The New England journal of medicine (19-06-2014)“…In patients with rheumatoid arthritis, tofacitinib was associated with greater reductions in signs and symptoms than methotrexate. Herpes zoster infections and…”
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2
Tofacitinib or Adalimumab versus Placebo in Rheumatoid Arthritis
Published in The New England journal of medicine (09-08-2012)“…In this trial of patients with rheumatoid arthritis who were on stable doses of methotrexate, tofacitinib, a novel oral Janus kinase inhibitor, was more…”
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3
Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial
Published in The Lancet (British edition) (09-02-2013)“…Summary Background Rheumatoid arthritis is a heterogeneous chronic disease, and no therapeutic agent has been identified which is universally and persistently…”
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4
Methods for Integrating Medication Compliance and Persistence in Pharmacoeconomic Evaluations
Published in Value in health (01-11-2007)“…Abstract Objectives Suboptimal compliance and failure to persist with drug treatments are important determinants of therapeutic nonresponse and are of…”
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Analgesic effectiveness of celecoxib and diclofenac in patients with osteoarthritis of the hip requiring joint replacement surgery: a 12-week, multicenter, randomized, double-blind, parallel-group, double-dummy, noninferiority study
Published in Clinical therapeutics (2008)“…Abstract Background: The hip is the second most common large joint that is affected by osteoarthritis (OA), with prevalence ranging from 3% to 11% in patients…”
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Tofacitinib in Combination With Nonbiologic Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis: A Randomized Trial
Published in Annals of internal medicine (20-08-2013)“…Many patients with rheumatoid arthritis (RA) do not achieve adequate and safe responses with disease-modifying antirheumatic drugs (DMARDs). Tofacitinib is a…”
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Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia
Published in The New England journal of medicine (29-07-2021)“…Patients who were hospitalized with Covid-19 pneumonia were randomly assigned, at a median of 10 days after symptom onset, to receive tofacitinib or placebo…”
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Tofacitinib or adalimumab versus placebo: patient-reported outcomes from a phase 3 study of active rheumatoid arthritis
Published in Rheumatology (Oxford, England) (01-06-2016)“…To evaluate effects of tofacitinib or adalimumab on patient-reported outcomes (PROs) in patients with moderate to severe RA and inadequate responses to MTX. In…”
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Evaluating the efficacy of sequential biologic therapies for rheumatoid arthritis patients with an inadequate response to tumor necrosis factor-α inhibitors
Published in Arthritis research & therapy (16-02-2011)“…The long-term treatment of rheumatoid arthritis (RA) most often involves a sequence of different therapies. The response to therapy, disease progression and…”
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Adherence to biologic DMARD therapies in rheumatoid arthritis
Published in Expert opinion on biological therapy (01-09-2010)“…The efficacy of the biologic disease-modifying antirheumatic drugs (DMARDs) shown in clinical trials may be jeopardized due to prevalent poor patient…”
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Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies
Published in International journal of rheumatic diseases (01-12-2016)“…Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here, the safety and efficacy data from five Phase 2 studies of…”
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Tofacitinib versus methotrexate in rheumatoid arthritis: patient-reported outcomes from the randomised phase III ORAL Start trial
Published in Rheumatic & musculoskeletal diseases open (2016)“…To compare patient-reported outcomes (PROs) in methotrexate (MTX)-naive patients (defined as no prior treatment or ≤3 doses) receiving tofacitinib versus MTX…”
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Measuring the effect of therapy in rheumatoid arthritis clinical trials from the patient's perspective
Published in Current medical research and opinion (01-07-2014)“…Abstract Objective: Health measurements used to evaluate the effectiveness of rheumatoid arthritis (RA) therapies often fail to reflect patients' priorities,…”
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Evaluating the efficacy of sequential biologic therapies for rheumatoid arthritis patients with an inadequate response to tumor necrosis factor-[alpha] inhibitors
Published in Arthritis research & therapy (16-02-2011)“…Introduction The long-term treatment of rheumatoid arthritis (RA) most often involves a sequence of different therapies. The response to therapy, disease…”
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15
Statistical Comments Are Unfounded
Published in Value in health (01-03-2008)Get full text
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16
Clinical and pharmacoeconomic impact of patient medication adherence
Published 01-01-2010“…This thesis addresses what is considered to be an important, yet often neglected aspect of pharmacoeconomic analyses: patient adherence with pharmacotherapy…”
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Dissertation -
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Gastroprotection in patients prescribed non-selective NSAIDs, and the risk of related hospitalization
Published in Current medical research and opinion (01-12-2008)“…ABSTRACT Objective: To assess co-prescription of gastroprotective agents (GPAs) for non-selective NSAID (nsNSAID)-treated patients in UK primary care, and the…”
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medR: Software System for Managing Medical History and Patient Examination Data
Published in 2021 IEEE 19th International Symposium on Intelligent Systems and Informatics (SISY) (16-09-2021)“…The purpose of the medR project is to lighten the burden on the local healthcare system given by the sub-optimal handling of large amounts of information. The…”
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Conference Proceeding -
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Economic evaluation of population-based mass screening for the early detection of cancer: a systematic review
Published in Magyar onkologia (2002)“…The increasing premature mortality due to cancer has made population based screening programs for cervical,breast and colorectal cancers inevitable in Hungary…”
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Journal Article