Search Results - "Konan, Kouacou V"

Sphingolipids as Potential Therapeutic Targets against Enveloped Human RNA Viruses by Yager, Eric J., Konan, Kouacou V.

“…Several notable human diseases are caused by enveloped RNA viruses: Influenza, AIDS, hepatitis C, dengue hemorrhagic fever, microcephaly, and Guillain–Barré…”
Get full text

Modulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2 by Khan, Irfan, Katikaneni, Divya S, Han, Qingxia, Sanchez-Felipe, Lorena, Hanada, Kentaro, Ambrose, Rebecca L, Mackenzie, Jason M, Konan, Kouacou V

“…Hepatitis C virus (HCV) assembles its replication complex on cytosolic membrane vesicles often clustered in a membranous web (MW). During infection, HCV NS5A…”
Get full text

Modulation of Hepatitis C Virus Genome Encapsidation by Nonstructural Protein 4B by Han, Qingxia, Manna, David, Belton, Kerry, Cole, Richard, Konan, Kouacou V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Participation of Rab5, an Early Endosome Protein, in Hepatitis C Virus RNA Replication Machinery by Stone, Michelle, Jia, Shuaizheng, Heo, Won Do, Meyer, Tobias, Konan, Kouacou V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Endocytic Rab proteins are required for hepatitis C virus replication complex formation by Manna, David, Aligo, Jason, Xu, Chenjia, Park, Wei Sun, Koc, Hasan, Do Heo, Won, Konan, Kouacou V

“…Abstract During infection, hepatitis C virus (HCV) NS4B protein remodels host membranes to form HCV replication complexes (RC) which appear as foci under…”
Get full text

Formation and function of hepatitis C virus replication complexes require residues in the carboxy-terminal domain of NS4B protein by Aligo, Jason, Jia, Shuaizheng, Manna, David, Konan, Kouacou V

“…Abstract During replication, hepatitis C virus (HCV) NS4B protein rearranges intracellular membranes to form foci, or the web, the putative site for HCV…”
Get full text

Conserved GXXXG- and S/T-Like Motifs in the Transmembrane Domains of NS4B Protein Are Required for Hepatitis C Virus Replication by QINGXIA HAN, ALIGO, Jason, MANNA, David, BELTON, Kerry, CHINTAPALLI, Sree V, HONG, Yoojin, PATTERSON, Randen L, VAN ROSSUM, Damian B, KONAN, Kouacou V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Bovine viral diarrhea virus NS4B protein is an integral membrane protein associated with Golgi markers and rearranged host membranes by Weiskircher, Erica, Aligo, Jason, Ning, Gang, Konan, Kouacou V

“…Very little is known about BVDV NS4B, a protein of approximately 38 kDa. However, a missense mutation in NS4B has been implicated in changing BVDV from a…”
Get full text

Nonstructural Protein Precursor NS4A/B from Hepatitis C Virus Alters Function and Ultrastructure of Host Secretory Apparatus by Konan, Kouacou V, Giddings, Jr, Thomas H, Ikeda, Masanori, Li, Kui, Lemon, Stanley M, Kirkegaard, Karla

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Modulation of Zika virus replication via glycosphingolipids by Konan, Kouacou V., Ogbamikael, Simon Alem, Yager, Eric, Yamaji, Toshiyuki, Cerone, Jennifer, Monaco-Brown, Meredith, Barroso, Margarida, Hanada, Kentaro

“…The enveloped positive-sense RNA viruses including Zika virus (ZIKV) need host lipids to successfully replicate. The nature of the lipids and the replication…”
Get full text

Hepatitis C Virus NS4B Can Suppress STING Accumulation To Evade Innate Immune Responses by Yi, Guanghui, Wen, Yahong, Shu, Chang, Han, Qingxia, Konan, Kouacou V, Li, Pingwei, Kao, C Cheng

“…The cyclic dinucleotide 2',3'-cGAMP can bind the adaptor protein STING (stimulator of interferon [IFN] genes) to activate the production of type I IFNs and…”
Get full text

Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection by Guévin, Carl, Manna, David, Bélanger, Claudia, Konan, Kouacou V, Mak, Paul, Labonté, Patrick

“…Abstract Autophagy is an important cellular process by which ATG5 initiates the formation of double membrane vesicles (DMVs). Upon infection, DMVs have been…”
Get full text

Lipids and RNA virus replication by Konan, Kouacou V, Sanchez-Felipe, Lorena

“…•Fatty acids provide additional phospholipids in the replicase factory.•PI4P stimulates virus proteins and recruits effectors crucial for RNA…”
Get full text

Correction for Yi et al., "Hepatitis C Virus NS4B Can Suppress STING Accumulation To Evade Innate Immune Responses" by Yi, Guanghui, Wen, Yahong, Shu, Chang, Han, Qingxia, Konan, Kouacou V, Li, Pingwei, Kao, C Cheng

Get full text

Importance of the Two Interferon-stimulated Response Element (ISRE) Sequences in the Regulation of the Human Indoleamine 2,3-Dioxygenase Gene by Konan, K V, Taylor, M W

“…Indoleamine 2,3-dioxygenase (INDO) is the rate-limiting enzyme in the catabolism of the essential amino acid L -tryptophan. It is induced strongly in many cell…”
Get full text

New Insights Into The Molecular And Cellular Biology Of Hepatitis C Virus by Konan, Kouacou V.

“…Hepatitis C virus (HCV) is the major cause of chronic hepatitis worldwide. Cloned in 1989 (Sci. 244, 359–362), HCV genome is now well characterized. HCV is a…”
Get full text

Treatment of ME180 cells with interferon-gamma causes apoptosis as a result of tryptophan starvation by Konan, K V, Taylor, M W

“…Indoleamine 2'3 dioxygenase (INDO), the rate-limiting enzyme in the catabolism of the essential amino acid L-tryptophan, is induced in many cell lines…”
Get more information