Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic

Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patien...

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Bibliographic Details
Published in:	BMC research notes Vol. 4; no. 1; p. 543
Main Authors:	Manirakiza, Alexandre, Boas, Susana Vilas, Beyam, Narcisse, Zadanga, Germain, Konamna, François Xavier, Njuimo, Siméon P, Laganier, Rémi
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 15-12-2011 BioMed Central BMC
Subjects:	Antibacterial agents Central African Republic Clinical outcomes Health aspects Life Sciences Santé publique et épidémiologie Short Report Skin Treatment Yaws Yaws Treatment Central African Republic
Online Access:	Get full text
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Summary:	Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region. The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1756-0500 1756-0500
DOI:	10.1186/1756-0500-4-543