Search Results - "Komune, Shizuo"

Clinical Significance of miR-146a in Gastric Cancer Cases by KOGO, Ryunosuke, MIMORI, Koshi, TANAKA, Fumiaki, KOMUNE, Shizuo, MORI, Masaki

“…The profiles of microRNAs change significantly in gastric cancer. MiR-146a is reported to be a tumor suppressor in pancreatic cancer, breast cancer, and…”
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Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution by Uchi, Ryutaro, Takahashi, Yusuke, Niida, Atsushi, Shimamura, Teppei, Hirata, Hidenari, Sugimachi, Keishi, Sawada, Genta, Iwaya, Takeshi, Kurashige, Junji, Shinden, Yoshiaki, Iguchi, Tomohiro, Eguchi, Hidetoshi, Chiba, Kenichi, Shiraishi, Yuichi, Nagae, Genta, Yoshida, Kenichi, Nagata, Yasunobu, Haeno, Hiroshi, Yamamoto, Hirofumi, Ishii, Hideshi, Doki, Yuichiro, Iinuma, Hisae, Sasaki, Shin, Nagayama, Satoshi, Yamada, Kazutaka, Yachida, Shinichi, Kato, Mamoru, Shibata, Tatsuhiro, Oki, Eiji, Saeki, Hiroshi, Shirabe, Ken, Oda, Yoshinao, Maehara, Yoshihiko, Komune, Shizuo, Mori, Masaki, Suzuki, Yutaka, Yamamoto, Ken, Aburatani, Hiroyuki, Ogawa, Seishi, Miyano, Satoru, Mimori, Koshi

“…Understanding intratumor heterogeneity is clinically important because it could cause therapeutic failure by fostering evolutionary adaptation. To this end, we…”
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A microsensing system for the in vivo real-time detection of local drug kinetics by Ogata, Genki, Ishii, Yuya, Asai, Kai, Sano, Yamato, Nin, Fumiaki, Yoshida, Takamasa, Higuchi, Taiga, Sawamura, Seishiro, Ota, Takeru, Hori, Karin, Maeda, Kazuya, Komune, Shizuo, Doi, Katsumi, Takai, Madoka, Findlay, Ian, Kusuhara, Hiroyuki, Einaga, Yasuaki, Hibino, Hiroshi

“…Real-time recording of the kinetics of systemically administered drugs in in vivo microenvironments may accelerate the development of effective medical…”
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A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment by Nakagawa, Takayuki, Kumakawa, Kozo, Usami, Shin-ichi, Hato, Naohito, Tabuchi, Keiji, Takahashi, Mariko, Fujiwara, Keizo, Sasaki, Akira, Komune, Shizuo, Sakamoto, Tatsunori, Hiraumi, Harukazu, Yamamoto, Norio, Tanaka, Shiro, Tada, Harue, Yamamoto, Michio, Yonezawa, Atsushi, Ito-Ihara, Toshiko, Ikeda, Takafumi, Shimizu, Akira, Tabata, Yasuhiko, Ito, Juichi

“…To date, no therapeutic option has been established for sudden deafness refractory to systemic corticosteroids. This study aimed to examine the efficacy and…”
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Spatiotemporal signatures of an abnormal auditory system in stuttering by Kikuchi, Yoshikazu, Ogata, Katsuya, Umesaki, Toshirou, Yoshiura, Takashi, Kenjo, Masamutsu, Hirano, Yoji, Okamoto, Tsuyoshi, Komune, Shizuo, Tobimatsu, Shozo

“…People who stutter (PWS) can reduce their stuttering rates under masking noise and altered auditory feedback; such a response can be attributed to altered…”
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Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells by Tsuchihashi, Nana Akagi, Hayashi, Ken, Dan, Katsuaki, Goto, Fumiyuki, Nomura, Yasuyuki, Fujioka, Masato, Kanzaki, Sho, Komune, Shizuo, Ogawa, Kaoru

“…The aim of this study was to determine whether autophagy and AMPK contribute to premature senescence in auditory cells. Incubating HEI-OC1 auditory cells with…”
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Neuromagnetic detection of the laryngeal area: Sensory-evoked fields to air-puff stimulation by Miyaji, Hideaki, Hironaga, Naruhito, Umezaki, Toshiro, Hagiwara, Koichi, Shigeto, Hiroshi, Sawatsubashi, Motohiro, Tobimatsu, Shozo, Komune, Shizuo

“…The sensory projections from the oral cavity, pharynx, and larynx are crucial in assuring safe deglutition, coughing, breathing, and voice production/speaking…”
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A Surgical Navigation System for Guiding Exact Cochleostomy Using Auditory Feedback : A Clinical Feasibility Study by Cho, Byunghyun, Matsumoto, Nozomu, Komune, Shizuo, Hashizume, Makoto

“…In cochlear implantation (CI), the insertion of the electrode array into the appropriate compartment of the cochlea, the scala tympani, is important for an…”
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Molecular architecture of the stria vascularis membrane transport system, which is essential for physiological functions of the mammalian cochlea by Uetsuka, Satoru, Ogata, Genki, Nagamori, Shushi, Isozumi, Noriyoshi, Nin, Fumiaki, Yoshida, Takamasa, Komune, Shizuo, Kitahara, Tadashi, Kikkawa, Yoshiaki, Inohara, Hidenori, Kanai, Yoshikatsu, Hibino, Hiroshi

“…Stria vascularis of the mammalian cochlea transports K+ to establish the electrochemical property in the endolymph crucial for hearing. This epithelial tissue…”
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Mice lacking ganglioside GM3 synthase exhibit complete hearing loss due to selective degeneration of the organ of Corti by Yoshikawa, Misato, Go, Shinji, Takasaki, Kotaro, Kakazu, Yasuhiro, Ohashi, Mitsuru, Nagafuku, Masakazu, Kabayama, Kazuya, Sekimoto, Junji, Suzuki, Shun-ichi, Takaiwa, Kazutaka, Kimitsuki, Takashi, Matsumoto, Nozomu, Komune, Shizuo, Kamei, Daisuke, Saito, Masaki, Fujiwara, Michihiro, Iwasaki, Katsunori, Inokuchi, Jin-ichi

“…The ganglioside GM3 synthase (SAT-I), encoded by a single-copy gene, is a primary glycosyltransferase for the synthesis of complex gangliosides. In SAT-I null…”
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Safety and efficacy of a new regimen of short-term oral immunotherapy with Cry j 1-galactomannan conjugate for Japanese cedar pollinosis: A prospective, randomized, open-label study by Murakami, Daisuke, Sawatsubashi, Motohiro, Kikkawa, Sayaka, Ejima, Masayoshi, Saito, Akira, Kato, Akio, Komune, Shizuo

“…Short-term oral immunotherapy (OIT) using the Cry j1-galactomannan conjugate for Japanese cedar pollinosis may be effective and relatively safe. However, a…”
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Molecular subclassification determined by human papillomavirus and epidermal growth factor receptor status is associated with the prognosis of oropharyngeal squamous cell carcinoma by Nakano, Takafumi, MD, PhD, Yamamoto, Hidetaka, MD, PhD, Nakashima, Torahiko, MD, PhD, Nishijima, Toshimitsu, MD, Satoh, Masanobu, MD, Hatanaka, Yui, MD, Shiratsuchi, Hideki, MD, PhD, Yasumatsu, Ryuji, MD, PhD, Toh, Satoshi, MD, PhD, Komune, Shizuo, MD, PhD, Oda, Yoshinao, MD, PhD

“…Summary Human papillomavirus (HPV) infection is an indicator of good response to chemoradiotherapy in oropharyngeal squamous cell carcinoma (OPSCC), and…”
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HER2 and EGFR gene copy number alterations are predominant in high-grade salivary mucoepidermoid carcinoma irrespective of MAML2 fusion status by Nakano, Takafumi, Yamamoto, Hidetaka, Hashimoto, Kazuki, Tamiya, Sadafumi, Shiratsuchi, Hideki, Nakashima, Torahiko, Nishiyama, Ken-ichi, Higaki, Yuichiro, Komune, Shizuo, Oda, Yoshinao

“…Aims In this study, we aimed to investigate the molecular mechanisms underlying the development of mucoepidermoid carcinoma (MEC). Methods and results In 31…”
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Musashi-1 is the candidate of the regulator of hair cell progenitors during inner ear regeneration by Wakasaki, Takahiro, Niiro, Hiroaki, Jabbarzadeh-Tabrizi, Siamak, Ohashi, Mitsuru, Kimitsuki, Takashi, Nakagawa, Takashi, Komune, Shizuo, Akashi, Koichi

“…Hair cell loss in the cochlea is caused by ototoxic drugs, aging, and environmental stresses and could potentially lead to devastating pathophysiological…”
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Author Correction: Computer modeling defines the system driving a constant current crucial for homeostasis in the mammalian cochlea by integrating unique ion transports by Nin, Fumiaki, Yoshida, Takamasa, Murakami, Shingo, Ogata, Genki, Uetsuka, Satoru, Choi, Samuel, Doi, Katsumi, Sawamura, Seishiro, Inohara, Hidenori, Komune, Shizuo, Kurachi, Yoshihisa, Hibino, Hiroshi

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A minimally invasive registration method using Surface Template-Assisted Marker Positioning (STAMP) for image-guided otologic surgery by Matsumoto, Nozomu, Hong, Jaesung, Hashizume, Makoto, Komune, Shizuo

“…A new, minimally invasive registration method was developed for image-guided otologic surgery. We utilized laser-sintered template of the patient's bone…”
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Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo by Noda, Teppei, Oki, Shinya, Kitajima, Keiko, Harada, Tetsuro, Komune, Shizuo, Meno, Chikara

“…The mouse inner ear develops from a simple epithelial pouch, the otocyst, with the dorsal and ventral portions giving rise to the vestibule and cochlea,…”
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HER-2/neu gene amplification in carcinoma ex pleomorphic adenoma in relation to progression and prognosis: a chromogenic in-situ hybridization study by Hashimoto, Kazuki, Yamamoto, Hidetaka, Shiratsuchi, Hideki, Nakashima, Torahiko, Tamiya, Sadafumi, Nishiyama, Ken-ichi, Higaki, Yuichiro, Komune, Shizuo, Tsuneyoshi, Masazumi, Oda, Yoshinao

“…Hashimoto K, Yamamoto H, Shiratsuchi H, Nakashima T, Tamiya S, Nishiyama K, Higaki Y, Komune S, Tsuneyoshi M & Oda Y (2012) Histopathology 60, E131–E142 neu…”
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Inflammatory pseudotumor in head and neck by Segawa, Yuichi, Yasumatsu, Ryuji, Shiratsuchi, Hideki, Tamae, Akihiro, Noda, Teppei, Yamamoto, Hidetaka, Komune, Shizuo

“…Abstract Background Inflammatory pseudotumor (IPT) is a tumefactive lesion characterized by fibroblastic proliferations and a prominent inflammatory component…”
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Videofluoroscopic assessment of pharyngeal stage delay reflects pathophysiology after brain infarction by Miyaji, Hideaki, Umezaki, Toshiro, Adachi, Kazuo, Sawatsubashi, Motohiro, Kiyohara, Hideyuki, Inoguchi, Takashi, To, Satoshi, Komune, Shizuo

“…Objectives/Hypothesis: The pathophysiology of dysphagia caused by brain infarction varies with the site of the lesion in the brain. Patients with suprabulbar…”
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