Search Results - "Komsuoglu Celikyurt, Ipek"

An update of anti-viral treatment of COVID-19 by Şimşek-Yavuz, Serap, Komsuoğlu Çelikyurt, Feride Ipek

“…Currently there is not an effective antiviral treatment for COVID-19, but a large number of drugs have been evaluated since the beginning of the pandemic, and…”
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Inhibition of PDE4 by low doses of rolipram induces changes in lipid and protein components of mice heart by Türker-Kaya, Sevgi, Komsuoğlu Celikyurt, İpek, Celikyurt, Umut, Kına, Aygül

“…There is significant increasing interest in phosphodiesterase-4 (PDE4) inhibition in treatment of cardiovascular diseases. Related with this, research has…”
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Availability, use and development of animal models for the assessment of drug-drug interactions and safety of direct oral anticoagulants by Ipek KOMSUOGLU CELIKYURT

“…Direct oral anticoagulants (DOACs) are novel, direct acting drugs that are selective for either thrombin or activated factor X. Due to their obvious benefits…”
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Exenatide upregulates gene expression of glucagon‐like peptide‐1 receptor and nerve growth factor in streptozotocin/nicotinamide‐induced diabetic mice by Gumuslu, Esen, Cine, Naci, Ertan, Merve, Mutlu, Oguz, Komsuoglu Celikyurt, Ipek, Ulak, Guner

“…Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone that has modulating effects on insulin release. GLP‐1 and receptors for GLP‐1 are widely expressed…”
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Beneficial effects of resveratrol on scopolamine but not mecamylamine induced memory impairment in the passive avoidance and Morris water maze tests in rats by Gacar, Nejat, Mutlu, Oguz, Utkan, Tijen, Komsuoglu Celikyurt, Ipek, Gocmez, Semil Selcen, Ulak, Güner

“…Resveratrol (3,5,4-trihydroxy-trans-stilbene), which is found in grapes and red wine has been shown to protect neuronal cells with its antioxidant activity,…”
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Exenatide Alters Gene Expression of Neural Cell Adhesion Molecule (NCAM), Intercellular Cell Adhesion Molecule (ICAM), and Vascular Cell Adhesion Molecule (VCAM) in the Hippocampus of Type 2 Diabetic Model Mice by Gumuslu, Esen, Cine, Naci, Ertan Gökbayrak, Merve, Mutlu, Oguz, Komsuoglu Celikyurt, Ipek, Ulak, Guner

“…BACKGROUND Glucagon-like peptide-1 (GLP-1), a potent and selective agonist for the GLP-1 receptor, ameliorates the symptoms of diabetes through stimulation of…”
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Effects of YC-1 on learning and memory functions of aged rats by Komsuoglu Celikyurt, Ipek, Utkan, Tijen, Ozer, Cuneyt, Gacar, Nejat, Aricioglu, Feyza

“…The aim of this study was to investigate the effects of a potent nitric oxide-guanylate cyclase activator, 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole…”
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Effects of olanzapine, sertindole and clozapine on learning and memory in the Morris water maze test in naive and MK-801-treated mice by Mutlu, Oguz, Ulak, Güner, Celikyurt, Ipek Komsuoglu, Akar, Füruzan Yıldız, Erden, Faruk

“…Cognitive dysfunction in schizophrenia is associated with functional disease symptoms. The beneficial effects of second generation antipsychotic drugs on…”
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Involvement of serotonin receptor subtypes in the antidepressant-like effect of beta receptor agonist Amibegron (SR 58611A): An experimental study by Tanyeri, Pelin, Buyukokuroglu, Mehmet Emin, Mutlu, Oguz, Ulak, Güner, Yıldız Akar, Füruzan, Komsuoglu Celikyurt, Ipek, Erden, Bekir Faruk

“…New therapeutic strategies against depression, with less side effects and thus greater efficacy in larger proportion of depressed patients, are needed…”
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Exenatide treatment exerts anxiolytic- and antidepressant-like effects and reverses neuropathy in a mouse model of type-2 diabetes by Komsuoglu Celikyurt, Ipek, Mutlu, Oguz, Ulak, Guner, Uyar, Emre, Bektaş, Emine, Yildiz Akar, Furuzan, Erden, Faruk, Tarkun, Ilhan

“…Comorbid neurobehavioral disturbances and type-2 diabetes mellitus (T2DM) warrant immediate research attention. Exenatide, which is a potent and selective…”
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7-NI and ODQ Disturbs Memory in the Elevated Plus Maze, Morris Water Maze, and Radial Arm Maze Tests in Mice by Mutlu, Oguz, Akar, Furuzan, Celikyurt, Ipek Komsuoglu, Tanyeri, Pelin, Ulak, Guner, Erden, Faruk

“…Nitric oxide (NO) is an atypical neurotransmitter that causes changes in cognition. Nitric oxide synthase (NOS) and guanylate cyclase (GC) inhibitors have been…”
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Positive impact of levetiracetam on emotional learning and memory in naive mice by Celikyurt, Ipek Komsuoglu, Ulak, Guner, Mutlu, Oguz, Akar, Furuzan Yildiz, Mulayim, Serap, Erden, Faruk, Komsuoglu, Sezer Sener

“…The effect of an antiepileptic drug on cognitive function is of primary importance with respect to the patient's quality of life. Levetiracetam (LEV) is a…”
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Effects of a dragonfly (Anax i.) homeopathic remedy on learning, memory and cell morphology in mice by Mutlu, Oguz, Ulak, Guner, Kokturk, Sibel, Komsuoglu Celikyurt, Ipek, Tanyeri, Pelin, Akar, Furuzan, Erden, Faruk

“…Homeopathy is a form of alternative medicine in which uses highly diluted preparations that are believed to cause healthy people to exhibit symptoms similar to…”
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Effects of risperidone, quetiapine and ziprasidone on ethanol withdrawal syndrome in rats by Komsuoglu Celikyurt, Ipek, Kayir, Hakan, Ulak, Guner, Erden, Faruk B., Ulusoy, Gokhan K., Uzbay, Tayfun I.

“…Comorbid substance use in schizophrenic patients is common, and substance dependence is a predictive factor for psychosis. The present study was designed to…”
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Effects of 7-NI and ODQ on memory in the passive avoidance, novel object recognition, and social transmission of food preference tests in mice by Akar, Furuzan, Mutlu, Oguz, Komsuoglu Celikyurt, Ipek, Bektas, Emine, Tanyeri, Pelin, Ulak, Guner, Erden, Faruk

“…Nitric oxide (NO) is an intercellular messenger that plays a critical role in learning and memory processes. Effects of nitric oxide synthase (NOS) inhibitors…”
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Sildenafil enhances locomotor activity in young mice and exerts anxiogenic effects in both young and aged mice by Demirci, Deniz, Mutlu, Oguz, Akar, Furuzan, Komsuoglu Celikyurt, Ipek, Ulak, Guner

“…Sildenafil is a selective PDE5 inhibitor that increases cGMP levels in the target tissues and is an effective treatment agent for erectile dysfunction. The…”
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Zaprinast and rolipram enhances spatial and emotional memory in the elevated plus maze and passive avoidance tests and diminishes exploratory activity in naive mice by Akar, Furuzan, Mutlu, Oguz, Komsuoglu Celikyurt, Ipek, Ulak, Guner, Erden, Faruk, Bektas, Emine, Tanyeri, Pelin

“…Phosphodiesterase (PDE) inhibitors in the central nervous system have been shown to stimulate neuronal functions and increase neurogenesis in Alzheimer disease…”
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Effects of citalopram on cognitive performance in passive avoidance, elevated plus-maze and three-panel runway tasks in naïve rats by Mutlu, Oguz, Ulak, Guner, Celikyurt, Ipek Komsuoglu, Akar, Firuzan Yildiz, Erden, Faruk

“…Recent studies have shown that learning and memory capacity is disturbed in depressive patients, and it is important to reveal the effects of antidepressant…”
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Effects of Acute Administration of Adipokinetic Hormone on Depression, Anxiety, Pain, Locomotion and Memory in Mice by Mutlu, Oguz, Ulak, Guner, Akar, Furuzan, Erden, Faruk, Celikyurt, Ipek Komsuoglu, Bektas, Emine, Tanyeri, Pelin, Kaya, Havva

“…The neurosecretory cells in the corpus cardiacum of insects synthesize a set of hormones that are called adipokinetic, hypertrehalosemic or hyperprolinemic…”
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Effects of fluoxetine, tianeptine and olanzapine on unpredictable chronic mild stress-induced depression-like behavior in mice by Mutlu, Oguz, Gumuslu, Esen, Ulak, Guner, Celikyurt, Ipek Komsuoglu, Kokturk, Sibel, Kır, Hale Maral, Akar, Furuzan, Erden, Faruk

“…Tianeptine is an atypical antidepressant drug that has a different mechanism of action than other antidepressants. Olanzapine is an atypical antipsychotic drug…”
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