Search Results - "Komsta, Lukasz"

Analysis of phenolic compounds and antioxidant activity of methanolic extracts from inflorescences of Carduus sp by Kozyra, Małgorzata, Komsta, Łukasz, Wojtanowski, Krzysztof

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Chemometrics in pharmaceutical analysis by Komsta, Lukasz

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Aversive Learning Deficits and Depressive-Like Behaviors Are Accompanied by an Increase in Oxidative Stress in a Rat Model of Fetal Alcohol Spectrum Disorders: The Protective Effect of Rapamycin by Lopatynska-Mazurek, Malgorzata, Komsta, Lukasz, Gibula-Tarlowska, Ewa, Kotlinska, Jolanta H.

“…Fetal alcohol spectrum disorders (FASDs) are one of the most common consequences of ethanol exposure during pregnancy. In adulthood, these disorders can be…”
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Maternal Separation Alters Ethanol Drinking and Reversal Learning Processes in Adolescent Rats: The Impact of Sex and Glycine Transporter Type 1 (GlyT1) Inhibitor by Filarowska-Jurko, Joanna, Komsta, Lukasz, Smaga, Irena, Surowka, Paulina, Marszalek-Grabska, Marta, Grochecki, Pawel, Nizio, Dorota, Filip, Malgorzata, Kotlinska, Jolanta H

“…Adverse early life experiences are associated with an enhanced risk for mental and physical health problems, including substance abuse. Despite clinical…”
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Chemometric and statistical evaluation of calibration curves in pharmaceutical analysis -- a short review on trends and Recommendations by Komsta, Lukasz

“…The calibration of an analytical method is a very important part of its development, and only the proper statistical and chemometric evaluation of the results,…”
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The stability and degradation kinetics of acetylsalicylic acid in different organic solutions revisited – an UHPLC–ESI-QTOF spectrometry study by Skibinski, Robert, Komsta, Lukasz

“…Ultra high performance liquid chromatography (UHPLC), coupled with accurate quadrupole-time-of-flight (Q-TOF) mass spectrometry, was used for the stability…”
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Application of curve resolution algorithms in the study of drug photodegradation kinetics -- the example of moclobemide by Skibinski, Robert, Komsta, Lukasz

“…The photodegradation of moclobemide was studied in methanolic media. Ultra-HPLC (UHPLC)/MS/MS analysis proved decomposition to 4-chlorobenzamide as a major…”
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Stability-indicating validated HPLC method for simultaneous determination of oral antidiabetic drugs from thiazolidinedione and sulfonylurea groups in combined dosage forms by Gumieniczek, Anna, Berecka, Anna, Komsta, Łukasz

“…For type 2 diabetes treatment, combinations of drugs from the thiazolidinedione and sulfonylurea groups are now available in the same tablet or capsule…”
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Black Tea Samples Origin Discrimination Using Analytical Investigations of Secondary Metabolites, Antiradical Scavenging Activity and Chemometric Approach by Koch, Wojciech, Kukula-Koch, Wirginia, Komsta, Łukasz

“…A comprehensive study on the composition and antioxidant properties of black tea samples with a chemometric approach was performed via LC-ESI-Q-TOF-MS, DPPH…”
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Green Tea Quality Evaluation Based on Its Catechins and Metals Composition in Combination with Chemometric Analysis by Koch, Wojciech, Kukula-Koch, Wirginia, Komsta, Łukasz, Marzec, Zbigniew, Szwerc, Wojciech, Głowniak, Kazimierz

“…Green tea infusions are one of the most popular beverages consumed across the world, especially is Asian countries. Green tea quality is primarily based on…”
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Directional median analysis by Komsta, Łukasz

“…The Directional Median Analysis is a new proposal of robust data exploration. It can be treated as a multivariate extension of the idea similar to Theil–Sen…”
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Novel Hyperspectral Analysis of Thin-Layer Chromatographic Plates-An Application to Fingerprinting of 70 Polish Grasses by Wróbel-Szkolak, Joanna, Cwener, Anna, Komsta, Łukasz

“…The advantages of hyperspectral imaging in videodensitometry are presented and discussed with the example of extracts from 70 Polish grasses. An inexpensive…”
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Being uncertain in thin layer chromatography—Some thoughts about latent details in the retention estimation by Komsta, Lukasz

“…This paper deals with some important (but often neglected) details about the uncertainty of retention measurement in thin layer chromatography, the propagation…”
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Being Uncertain in Chromatographic Calibration—Some Unobvious Details in Experimental Design by Komsta, Łukasz, Wicha-Komsta, Katarzyna, Kocki, Tomasz

“…This is an introductory tutorial and review about the uncertainty problem in chromatographic calibration. It emphasizes some unobvious, but important details…”
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Separation of fibrate-type antihyperlipidemic drugs by capillary electrophoresis and their quantitation in pharmaceuticals by Komsta, Łukasz, Misztal, Genowefa, Majchrzak, Ewa, Hauzer, Agnieszka

“…Six antihyperlipidemic agents—bezafibrate, ciprofibrate, clofibrate, clofibric acid, fenofibrate and gemfibrozil were separated by means of capillary…”
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Effect of ACEA 1021 on Neurotoxicity Induced by Dexamethasone — Initial Behavioral Study by Krasuska-Grzegorczyk, Beata, Komsta, Łukasz, Danilczuk, Zofia

“…Considerable evidence suggests that glucocorticoids (GCs) play an important role in neurodegeneration. Chronic elevated levels of GCs can result in neuronal…”
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Multivariate look at the TLC retention: A concise review by Komsta, Lukasz

“…The multivariate analysis of retention data in thin-layer chromatography (TLC) allows the chromatographer to visualize the multidimensional retention data and…”
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Multivariate Chemometric Comparison of Forced Degradation and Electrochemical Oxidation LC-MS Profiles of Maraviroc by Wroński, Michał, Trawiński, Jakub, Komsta, Łukasz, Skibiński, Robert

“…In this study, nine forced degradation products of maraviroc were found using chemometric analysis. This antiretroviral drug was subjected to photolytic,…”
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Novel computational approaches to retention modeling in dual hydrophilic interactions/reversed phase chromatography by Obradović, Darija, Komsta, Łukasz, Agbaba, Danica

“…•Mathematical description of mixed-mode retention with the use of Box-Cox transformation.•Introduction of novel mixed-mode retention parameters.•Evaluation of…”
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Detection of drug active ingredients by chemometric processing of solid-state NMR spectrometry data -- the case of acetaminophen by Paradowska, Katarzyna, Jamróz, Marta Katarzyna, Kobyłka, Mariola, Gowin, Ewelina, Maczka, Paulina, Skibiński, Robert, Komsta, Łukasz

“…This paper presents a preliminary study in building discriminant models from solid-state NMR spectrometry data to detect the presence of acetaminophen in…”
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