Search Results - "Komor, Roman"
-
1
Synthesis and Preliminary Evaluation of Biological Activity of Glycoconjugates Analogues of Acyclic Uridine Derivatives
Published in Molecules (Basel, Switzerland) (13-08-2018)“…Herein we present the methodology for obtaining glycosyltransferase inhibitors, analogues of natural enzyme substrates of donor-type: UDP-glucose and…”
Get full text
Journal Article -
2
Amino-phenol complexes of Fe(III) as promising T1 accelerators
Published in Arabian journal of chemistry (01-11-2019)“…Iron(III) complexes of pentadentate N,O-ligands are obtained. T1 of water is highly accelerated by the complexes. Extreme relaxivity is observed in serum and…”
Get full text
Journal Article -
3
A new class of bioactivable self-immolative N,O-ligands
Published in European journal of medicinal chemistry (01-06-2012)“…A hexadentate ligand built on an amine-bis(phenol) skeleton with an aminal, self-immolative moiety is presented. Synthesis of the ligand is convenient and…”
Get full text
Journal Article -
4
Synthesis and preliminary biological assay of uridine glycoconjugate derivatives containing amide and/or 1,2,3-triazole linkers
Published in Bioorganic chemistry (01-06-2017)“…[Display omitted] •Type of linker replacing of pyrophosphate part determines the biological activity.•Glycoconjugate with O-methylene triazole unit is able to…”
Get full text
Journal Article -
5
An approach for disaccharide chiron synthesis using a Ferrier-type rearrangement
Published in Tetrahedron letters (02-07-2014)“…We report a new approach for the synthesis of new chiral synthons in which two unsaturated sugars are linked via a glycosidic bond. The di-unsaturated…”
Get full text
Journal Article -
6
Synthesis of fucosylated uridine conjugates as potential glycosyltransferase inhibitors
Published in Acta Poloniae pharmaceutica (01-11-2014)Get full text
Journal Article -
7
Application of different alpha-1-thioglycosides preparation methods in synthesis of 5-nitro-2-pyridyl 1-thioglycosides substrates in synthesis of conjugates with uridine moiety. Part I
Published in Acta Poloniae pharmaceutica (01-11-2012)“…The synthesis of (5-nitro-2-pyridyl) 2-deoxy-1-thioglycosides is presented. Obtained compounds were used in the synthesis of uridine derivatives, potential…”
Get full text
Journal Article -
8
Synthesis of genistein 2,3-anhydroglycoconjugates -- potential antiproliferative agents
Published in Acta Poloniae pharmaceutica (01-11-2012)“…The title compounds, variously protected 2.3-anhydrosugars linked with genistein through an alkyl chain, were synthesized in a sequence of reactions. First…”
Get full text
Journal Article -
9
5-Nitro-2-pyridyl-1-thioglucosides: application in synthesis of analogues of glycosyltransferases natural substrates
Published in Acta Poloniae pharmaceutica (01-11-2010)“…5-Nitro-2-pyridyl-1-thioglucosides were used in synthesis of complex uridine derivatives (13-16) in two different sequences of reactions. In one route, the…”
Get full text
Journal Article