Search Results - "Komkov, D. S."
-
1
Regulatory systems of chicken alpha-globin gene domain suppress bidirectional transcription
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-07-2022)“…•The RFP inserted into chicken a-globin gene cluster is transcribed only when it is inserted in the same direction as globin genes.•Insertion of RFP into…”
Get full text
Journal Article -
2
The RRE–Rev Module Has No Effect on the Packaging Efficiency of Cas9 and Gag Proteins into NanoMEDIC Virus-like Particles
Published in Doklady. Biological sciences (01-12-2023)“…Delivery of ribonucleoprotein complexes of Cas9 nuclease and guide RNA into target cells with virus-like particles (VLP) is one of the novel methods of genome…”
Get full text
Journal Article -
3
Donor DNA Modification with Cas9 Targeting Sites Improves the Efficiency of MTC34 Knock-in into the CXCR4 Locus
Published in Molecular biology (New York) (01-08-2024)“…To successfully apply the genome editing technology using the CRISPR/Cas9 system in the clinic, it is necessary to achieve a high efficiency of knock-in, which…”
Get full text
Journal Article -
4
Methods to Increase the Efficiency of Knock-in of a Construct Encoding the HIV-1 Fusion Inhibitor, MT-C34 Peptide, into the CXCR4 Locus in the CEM/R5 T Cell Line
Published in Molecular biology (New York) (01-08-2024)“…The low knock-in efficiency, especially in primary human cells, limits the use of the genome editing technology for therapeutic purposes, rendering it…”
Get full text
Journal Article -
5
Efficient Editing of the CXCR4 Locus Using Cas9 Ribonucleoprotein Complexes Stabilized with Polyglutamic Acid
Published in Doklady. Biological sciences (01-12-2023)“…Gene editing using the CRISPR/Cas9 system provides new opportunities to treat human diseases. Approaches aimed at increasing the efficiency of genome editing…”
Get full text
Journal Article -
6
Prospects for developing and implementing remote blood pressure monitoring in patients under dispensary follow-up
Published in Kardiovaskuli͡a︡rnai͡a︡ terapii͡a︡ i profilaktika (01-03-2022)“…Recently, the use of telemedicine technologies (TMT) in the healthcare has gained great importance. TMT is one of the ways to increase the healthcare…”
Get full text
Journal Article -
7
Establishment of an orthotopic tumor model in the mammary gland of BALB/C nude mice using human breast cancer MCF-7 cells and their VDAC-deficient derivatives
Published in Sibirskiĭ onkologicheskiĭ zhurnal (03-03-2022)“…Purpose to study the tumor-forming activity of wild-type MC F-7 cells carrying a full set of porins (VDAC 1, VDAC 2, VDAC 3), as well as their genetically…”
Get full text
Journal Article -
8
What Are the Realities of Prescription and Control of Antithrombotic Therapy in Atrial Fibrillation in Outpatient Practice?
Published in Kardiologiia (01-01-2015)“…We analyzed documentation of 648 outpatients with nonvalvular atrial fibrillation receiving ambulatory care in 3 cities in Russia (Moscow, Krasnodar, and…”
Get more information
Journal Article -
9
What physicians think and know about antithrombotic therapy in atrial fibrillation
Published in Kardiologiia (2014)“…We conducted an anonymous survey among 382 physicians (58% internists, 42% cardiologists) in order to obtain information on their opinion on various aspects of…”
Get more information
Journal Article -
10
Effektivnost' nablyudeniya patsientov s arterial'noy gipertenziey v otdeleniyakh (kabinetakh) meditsinskoy profilaktiki
Published in CardioSomatika (15-12-2015)“…Цель. Оценить эффективность наблюдения пациентов с артериальной гипертензией (АГ) в отделениях (кабинетах) медицинской профилактики.Материал и методы. Для…”
Get full text
Journal Article