Search Results - "Komiyama, Yuske"
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Primary syphilis with a tongue ulcer mimicking tongue cancer: a case report
Published in Journal of international medical research (01-03-2023)“…The main symptom in primary syphilis is a small, painless, sore or ulcer called a chancre on the penis, vagina, or around the anus, although chancres can…”
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2
The mutational spectrum in whole exon of p53 in oral squamous cell carcinoma and its clinical implications
Published in Scientific reports (15-12-2022)“…Mutations in p53 are common in human oral squamous cell carcinoma (OSCC). However, in previous analyses, only detection of mutant p53 protein using…”
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3
Effectiveness of cetuximab as preemptive postsurgical therapy for oral squamous cell carcinoma patients with major risk: a single‐center retrospective cohort study
Published in Investigational new drugs (01-06-2021)“…Summary A retrospective cohort study was performed to investigate the effectiveness of preemptive postsurgical therapy with cetuximab for patients with a major…”
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4
Difference between Keratinized- and Non-Keratinized-Originating Epithelium in the Process of Immune Escape of Oral Squamous Cell Carcinoma
Published in International journal of molecular sciences (01-04-2024)“…Immune checkpoint inhibitors (ICIs), including anti-programmed cell death 1 ligand 1 (PD-L1) antibodies, are significantly changing treatment strategies for…”
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5
Paclitaxel Potentiates the Anticancer Effect of Cetuximab by Enhancing Antibody-Dependent Cellular Cytotoxicity on Oral Squamous Cell Carcinoma Cells In Vitro
Published in International journal of molecular sciences (31-08-2020)“…Administration of cetuximab (C-mab) in combination with paclitaxel (PTX) has been used for patients with head and neck squamous cell carcinoma (SCC)…”
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6
Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice
Published in PloS one (14-10-2014)“…Hedgehog (Hh) signaling plays important roles in various development processes. This signaling is necessary for osteoblast formation during endochondral…”
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7
Identification of Binding Proteins for TSC22D1 Family Proteins Using Mass Spectrometry
Published in International journal of molecular sciences (09-10-2021)“…TSC-22 (TGF-β stimulated clone-22) has been reported to induce differentiation, growth inhibition, and apoptosis in various cells. TSC-22 is a member of a…”
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8
Whole Exome Sequencing of SMO , BRAF , PTCH1 and GNAS in Odontogenic Diseases
Published in In vivo (Athens) (01-11-2020)“…Odontogenic diseases are diagnosed based on clinical course, imaging, and histopathology. However, a definitive diagnosis is not always possible. We analyzed…”
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Stepwise Differentiation of Pluripotent Stem Cells into Osteoblasts Using Four Small Molecules under Serum-free and Feeder-free Conditions
Published in Stem cell reports (03-06-2014)“…Pluripotent stem cells are a promising tool for mechanistic studies of tissue development, drug screening, and cell-based therapies. Here, we report an…”
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10
Molecular and histopathological analysis of peripheral ameloblastoma of the mandible mimicking a papillomatous lesion on the buccal mucosa
Published in Journal of oral and maxillofacial surgery, medicine, and pathology (01-05-2022)“…An 89-year-old woman visited our hospital requesting the examination of a papillary mass in the posterior region of the right buccal mucosa. The…”
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11
Clinical characteristics, treatment methods and prognoses of patients with oral squamous cell carcinoma in Japanese population: a single institution retrospective cohort study
Published in BMC geriatrics (20-11-2020)“…The status of oral cancer therapy in elderly patients in Japan, where ageing is rapidly progressing, may serve as a model for other countries with similar…”
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12
A case of mandibular peripheral osteoma on the inferior border of the mandible
Published in Oral science international (01-09-2020)“…Reactive bone growth is often clinically difficult to distinguish from true tumors, and both types of lesion are frequently lumped together as “osteomas.” We…”
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13
Tenomodulin expression in the periodontal ligament enhances cellular adhesion
Published in PloS one (10-04-2013)“…Tenomodulin (Tnmd) is a type II transmembrane protein characteristically expressed in dense connective tissues such as tendons and ligaments. Its expression in…”
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14
Alterations of serum vitamin K levels and prothrombin time-international normalized ratio during tooth extractions among patients receiving warfarin
Published in Journal of oral and maxillofacial surgery, medicine, and pathology (01-11-2018)“…The British guideline described that antibiotic treatment during tooth extraction kills bacteria in the intestine, which reduces their production of vitamin K…”
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15
Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system
Published in Journal of bone and mineral metabolism (01-11-2010)“…To effectively treat degenerative joint diseases including osteoarthritis (OA), small chemical compounds need to be developed that can potently induce…”
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16
Development of high-throughput screening system for osteogenic drugs using a cell-based sensor
Published in Biochemical and biophysical research communications (14-11-2008)“…To effectively treat osteoporosis and other bone-loss disorders, small compounds that potently induce bone formation are needed. The present study initially…”
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Troglitazone, a Selective Ligand for PPARγ, Induces Cell-cycle Arrest in Human Oral SCC Cells
Published in Anticancer research (01-03-2020)“…We attempted to clarify the role of Peroxisome proliferator-activated receptor γ (PPARγ) and its ligand, troglitazone (TRO) on oral squamous cell carcinoma…”
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18
Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification
Published in The Journal of biological chemistry (18-05-2012)“…With regard to Hedgehog signaling in mammalian development, the majority of research has focused on Gli2 and Gli3 rather than Gli1. This is because Gli1−/−…”
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Abstract 1551: Determination of the origin of oral squamous cell carcinoma by microarray analysis
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract More than 90% of oral cancer is histopathologically squamous cell carcinoma (SCC). According to its clinical behavior and histopathological features,…”
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5,10‑Methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms in patients with nonsyndromic cleft lip and palate
Published in Biomedical reports (01-12-2020)“…Cleft lip with or without cleft palate (CL/P) is considered a multifactorial genetic disorder. Folic acid metabolism has been suggested to underlie the…”
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