Search Results - "Komatsu, Naoki"

Chemical Functionalization of Nanodiamonds: Opportunities and Challenges Ahead by Reina, Giacomo, Zhao, Li, Bianco, Alberto, Komatsu, Naoki

“…Nanodiamond(ND)‐based technologies are flourishing in a wide variety of fields spanning from electronics and optics to biomedicine. NDs are considered a family…”
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Quantitative investigation of the interaction between proteins and charged functional groups on the polyglycerol-grafted nanodiamond surface by Zou, Yajuan, Komatsu, Naoki

“…Interaction at the interface between protein and nanoparticle (NP) surface is of fundamental importance in nanomedicine, because protein corona formation on…”
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Polyglycerol Grafting Shields Nanoparticles from Protein Corona Formation to Avoid Macrophage Uptake by Zou, Yajuan, Ito, Shinji, Yoshino, Fumi, Suzuki, Yuta, Zhao, Li, Komatsu, Naoki

“…Upon contact with biofluids, proteins are quickly adsorbed onto the nanoparticle (NP) surface to form a protein corona, which initiates the opsonization and…”
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Diameter-selective extraction of single-walled carbon nanotubes by interlocking with Cu-tethered square nanobrackets by Cheng, Guoqing, Komatsu, Naoki

“…We have been working with carbon nanotube separation through host-guest chemistry. Herein, a new macrocyclic host molecule, Cu-tethered square nanobrackets, is…”
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Polyglycerol-coated nanodiamond as a macrophage-evading platform for selective drug delivery in cancer cells by Zhao, Li, Xu, Yong-Hong, Akasaka, Tsukasa, Abe, Shigeaki, Komatsu, Naoki, Watari, Fumio, Chen, Xiao

“…Abstract A successful targeted drug delivery device for cancer chemotherapy should ideally be able to avoid non-specific uptake by nonmalignant cells,…”
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Efficient and Scalable Production of 2D Material Dispersions using Hexahydroxytriphenylene as a Versatile Exfoliant and Dispersant by Liu, Gang, Komatsu, Naoki

“…Thin‐layer 2D materials have been attracting enormous interest, and various processes have been investigated to obtain these materials efficiently. In view of…”
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Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle by Sakaue-Sawano, Asako, Yo, Masahiro, Komatsu, Naoki, Hiratsuka, Toru, Kogure, Takako, Hoshida, Tetsushi, Goshima, Naoki, Matsuda, Michiyuki, Miyoshi, Hiroyuki, Miyawaki, Atsushi

“…Eukaryotic cells spend most of their life in interphase of the cell cycle. Understanding the rich diversity of metabolic and genomic regulation that occurs in…”
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Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma by Li, Tong-Fei, Li, Ke, Zhang, Quan, Wang, Chao, Yue, Yuan, Chen, Zhuo, Yuan, Shen-Jun, Liu, Xin, Wen, Yu, Han, Min, Komatsu, Naoki, Xu, Yong-Hong, Zhao, Li, Chen, Xiao

“…Glioblastoma (GBM) is the deadliest and most common type of primary brain tumor in adults with a grim prognosis despite multimodal treatments. Dendritic cell…”
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Chromatographic Separation of Highly Soluble Diamond Nanoparticles Prepared by Polyglycerol Grafting by Zhao, Li, Takimoto, Tatsuya, Ito, Masaaki, Kitagawa, Naoko, Kimura, Takahide, Komatsu, Naoki

“…Making even tiny diamonds valuable: Nanodiamonds (NDs) were covalently functionalized with hyperbranched polyglycerol (PG) by ring‐opening polymerization to…”
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A Comprehensive Review on Separation Methods and Techniques for Single-Walled Carbon Nanotubes by Komatsu, Naoki, Wang, Feng

“…Structural control of single-walled carbon nanotubes (SWNTs) is attracting enormous interest in view of their applications to nanoelectronics and nanooptics…”
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Stable expression of FRET biosensors: A new light in cancer research by Aoki, Kazuhiro, Komatsu, Naoki, Hirata, Eishu, Kamioka, Yuji, Matsuda, Michiyuki

“…The constituents of the oncogene signal transduction pathway are promising targets for anticancer drugs. Despite the wealth of available knowledge regarding…”
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Conjugation of Phenylboronic Acid Moiety through Multistep Organic Transformations on Nanodiamond Surface for an Anticancer Nanodrug for Boron Neutron Capture Therapy by Nishikawa, Masahiro, Kang, Heon Gyu, Zou, Yajuan, Takeuchi, Hidekazu, Matsuno, Naoyoshi, Suzuki, Minoru, Komatsu, Naoki

“…Detonation nanodiamonds (DNDs) have attracted considerable attention, in particular, in the field of nanomedicine due to their biocompatibility as well as…”
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Polyglycerol Functionalized 10B Enriched Boron Carbide Nanoparticle as an Effective Bimodal Anticancer Nanosensitizer for Boron Neutron Capture and Photothermal Therapies by Wang, Yuquan, Reina, Giacomo, Kang, Heon Gyu, Chen, Xiaoxiao, Zou, Yajuan, Ishikawa, Yoshie, Suzuki, Minoru, Komatsu, Naoki

“…Boron neutron capture therapy (BNCT) is a non‐invasive cancer treatment with little adverse effect utilizing nuclear fission of 10B upon neutron irradiation…”
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A FRET Biosensor for ROCK Based on a Consensus Substrate Sequence Identified by KISS Technology by Li, Chunjie, Imanishi, Ayako, Komatsu, Naoki, Terai, Kenta, Amano, Mutsuki, Kaibuchi, Kozo, Matsuda, Michiyuki

“…Genetically-encoded biosensors based on Förster/fluorescence resonance energy transfer (FRET) are versatile tools for studying the spatio-temporal regulation…”
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Stereochemistry of Carbon Nanotubes by Komatsu, Naoki

“…Although stereochemistry of carbon nanotubes (CNTs) has been discussed so far in some papers, no common terminology has existed for describing left- and…”
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Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes by Chen, Zhuo, Yuan, Shen-Jun, Li, Ke, Zhang, Quan, Li, Tong-Fei, An, Hui-Chao, Xu, Hua-Zhen, Yue, Yuan, Han, Min, Xu, Yong-Hong, Komatsu, Naoki, Zhao, Li, Chen, Xiao

“…Astrocytes are key stromal components in glioblastoma (GBM) and have complex interactions with the GBM cells (GBC) promoting the survival, progression and…”
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The Circadian Gene Per1 Plays an Important Role in Cell Growth and DNA Damage Control in Human Cancer Cells by Gery, Sigal, Komatsu, Naoki, Baldjyan, Lilit, Yu, Andrew, Koo, Danielle, Koeffler, H. Phillip

“…The Per1 gene is a core clock factor that plays an essential role in generating circadian rhythms. Recent data reveal that major biological pathways, including…”
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Hyperbranched Polyglycerol-Grafted Superparamagnetic Iron Oxide Nanoparticles: Synthesis, Characterization, Functionalization, Size Separation, Magnetic Properties, and Biological Applications by Zhao, Li, Chano, Tokuhiro, Morikawa, Shigehiro, Saito, Yukie, Shiino, Akihiko, Shimizu, Sawako, Maeda, Takuro, Irie, Takayoshi, Aonuma, Shuji, Okabe, Hidetoshi, Kimura, Takahide, Inubushi, Toshiro, Komatsu, Naoki

“…For biomedical application of nanoparticles, the surface chemical functionality is very important to impart additional functions, such as solubility and…”
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Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells by Xu, Hua-Zhen, Li, Tong-Fei, Wang, Chao, Ma, Yan, Liu, Yan, Zheng, Mei-Yan, Liu, Zhang-Jun-Yan, Chen, Jin-Bo, Li, Ke, Sun, Shi-Kuan, Komatsu, Naoki, Xu, Yong-Hong, Zhao, Li, Chen, Xiao

“…Tumor-associated macrophages (TAMs) are the most abundant stromal cells in the tumor microenvironment. Turning the TAMs against their host tumor cells is an…”
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Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer by Yuan, Shen-Jun, Xu, Yong-Hong, Wang, Chao, An, Hui-Chao, Xu, Hua-Zhen, Li, Ke, Komatsu, Naoki, Zhao, Li, Chen, Xiao

“…Triple negative breast cancer (TNBC) has the poorest prognosis of all breast cancer subtypes and is one of the most fatal diseases for women. Combining…”
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