Search Results - "Komatsu, Motoaki"

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes by Hasegawa, Kazuhiro, Wakino, Shu, Simic, Petra, Sakamaki, Yusuke, Minakuchi, Hitoshi, Fujimura, Keiko, Hosoya, Kozi, Komatsu, Motoaki, Kaneko, Yuka, Kanda, Takeshi, Kubota, Eiji, Tokuyama, Hirobumi, Hayashi, Koichi, Guarente, Leonard, Itoh, Hiroshi

“…Diabetic nephropathy is the most common cause of end-stage renal disease. Shu Wakino and colleagues now show that high-glucose conditions in the renal proximal…”
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The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease by Takahashi, Rina, Kanda, Takeshi, Komatsu, Motoaki, Itoh, Tomoaki, Minakuchi, Hitoshi, Urai, Hidenori, Kuroita, Tomohiro, Shigaki, Shuhei, Tsukamoto, Tasuku, Higuchi, Naoko, Ikeda, Minoru, Yamanaka, Risa, Yoshimura, Norito, Ono, Takashi, Yukioka, Hideo, Hasegawa, Kazuhiro, Tokuyama, Hirobumi, Wakino, Shu, Itoh, Hiroshi

“…Dysregulation of nicotinamide adenine dinucleotide (NAD +) metabolism contributes to the initiation and progression of age-associated diseases, including…”
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NNMT activation can contribute to the development of fatty liver disease by modulating the NAD+ metabolism by Komatsu, Motoaki, Kanda, Takeshi, Urai, Hidenori, Kurokochi, Arata, Kitahama, Rina, Shigaki, Shuhei, Ono, Takashi, Yukioka, Hideo, Hasegawa, Kazuhiro, Tokuyama, Hirobumi, Kawabe, Hiroshi, Wakino, Shu, Itoh, Hiroshi

“…Nicotinamide N-methyltransferase (NNMT) catalyses the reaction between nicotinamide (NAM) and S -adenosylmethionine to produce 1-methylnicotinamide and S…”
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Ceftazidime encephalopathy developed without the elevation of cerebrospinal fluid concentration of ceftazidime: A case report of two cases by Toda, Masataro, Yoshifuji, Ayumi, Hosoya, Koji, Taguchi, Kazuaki, Komatsu, Motoaki, Kobayashi, Emi, Fujii, Kentaro, Kato, Ai, Hasegawa, Naoki, Matsumoto, Kazuaki, Ryuzaki, Munekazu

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Glomerulonephritis Caused by Bartonella spp. Infective Endocarditis: The Difficulty and Importance of Differentiation from Anti-neutrophil Cytoplasmic Antibody-related Rapidly Progressive Glomerulonephritis by Yoshifuji, Ayumi, Hibino, Yuuka, Komatsu, Motoaki, Yasuda, Seiichi, Hosoya, Koji, Kobayashi, Emi, Baba, Yuko, Hirose, Shigemichi, Hashiguchi, Akinori, Kanno, Yoshihiko, Ryuzaki, Munekazu

“…A 65-year-old man with valvular disorder presented to his physician because of widespread purpura in both lower extremities. Blood tests showed elevated serum…”
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Factors associated with SARS-CoV-2 antibody titers and prognosis of breakthrough infection in hemodialysis patients by Toda, Masataro, Yoshifuji, Ayumi, Kikuchi, Kan, Koinuma, Masayoshi, Komatsu, Motoaki, Fujii, Kentaro, Kato, Ai, Kikuchi, Takahide, Nakazawa, Atsushi, Ryuzaki, Munekazu

“…Background The mortality rate of Coronavirus disease 2019 (COVID-19) is extremely high in hemodialysis patients (HDP). These patients also develop lower…”
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Clinical relevance of proteinuria selectivity index and fractional excretion of sodium in patients with nephrotic syndrome by Nakayama, Takashin, Azegami, Tatsuhiko, Yamaguchi, Shintaro, Hirano, Keita, Komatsu, Motoaki, Fujii, Kentaro, Futatsugi, Koji, Urai, Hidenori, Kawaguchi, Takahisa, Itoh, Tomoaki, Yoshimoto, Norifumi, Hagiwara, Aika, Hishikawa, Akihito, Matsuda, Hiroto, Ando, Takashi, Yamaji, Yasuyoshi, Murakami, Marohito, Hashiguchi, Akinori, Kaneko, Yuko, Yokoo, Takashi, Hayashi, Kaori

“…Proteinuria selectivity index (PSI) is a potential tool for histological classification and prediction of treatment response in nephrotic syndrome, but…”
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A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma by Kato, Ai, Yoshifuji, Ayumi, Komori, Kohji, Aoki, Kotaro, Taniyama, Daisuke, Komatsu, Motoaki, Fujii, Kentaro, Yamada, Kuniko, Ishii, Yoshikazu, Kikuchi, Takahide, Ryuzaki, Munekazu

“…A 70-year-old woman, who started on hemodialysis 7 months before for end-stage renal disease due to diabetic nephropathy and was diagnosed with symptomatic…”
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Negative conversion of T-SPOT results after hemodialysis: case series and literature review by Toda, Masataro, Yoshifuji, Ayumi, Hosoya, Koji, Komatsu, Motoaki, Hasegawa, Naoki, Ryuzaki, Munekazu

“…Abstract Background Latent tuberculosis infection (LTBI) affects 11.9% of outpatients under maintenance hemodialysis in Japan. In addition, the risk of…”
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Stair climbing–descending exercise following meals improves 24-hour glucose excursions in people with type 2 diabetes by Honda, Hiroto, Igaki, Makoto, Komatsu, Motoaki, Tanaka, Shin-ichiro, Takaishi, Tetsuo, Hayashi, Tatsuya

“…We aimed at evaluating the effect of short-duration stair climbing–descending exercise (ST-EX) on 24-hour blood glucose (BG) response in people with type 2…”
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Ghrelin protects against renal damages induced by angiotensin-II via an antioxidative stress mechanism in mice by Fujimura, Keiko, Wakino, Shu, Minakuchi, Hitoshi, Hasegawa, Kazuhiro, Hosoya, Koji, Komatsu, Motoaki, Kaneko, Yuka, Shinozuka, Keisuke, Washida, Naoki, Kanda, Takeshi, Tokuyama, Hirobumi, Hayashi, Koichi, Itoh, Hiroshi

“…We explored the renal protective effects by a gut peptide, Ghrelin. Daily peritoneal injection with Ghrelin ameliorated renal damages in continuously…”
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Chryseobacterium indologenes Peritonitis in a Peritoneal Dialysis Patient: A Case Report and Review of Literature by Miyakawa, Akira, Fujii, Kentaro, Kato, Ai, Sugi, Wataru, Yoshifuji, Ayumi, Komatsu, Motoaki, Ryuzaki, Munekazu

“…Peritonitis is one of the most important complications in patients with peritoneal dialysis (PD). Appropriate antibiotic treatment against PD-associated…”
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Patients with hemodialysis-induced hypoxemia had a poor prognosis of COVID-19 by Toda, Masataro, Yoshifuji, Ayumi, Fujii, Kentaro, Komatsu, Motoaki, Kato, Ai, Tamura, Ikue, Sugi, Wataru, Ryuzaki, Munekazu

“…We experienced that some hemodialysis (HD) patients with coronavirus disease 2019 (COVID-19) exacerbated hypoxemia during HD. Though HD-induced hypoxemia has…”
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Association between Physical Activity and Seasonal Variations in Metabolic and Vascular Function in Adults by Honda, Hiroto, Igaki, Makoto, Komatsu, Motoaki, Tanaka, Shin-ichiro

“…This article highlights the association between physical activity (PA) and seasonal variations in metabolic and vascular function in adults. Increasing PA is…”
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Effect of moderate-intensity seated exercise on the management of metabolic outcomes in hypertensive individuals with or without exercise habits by Honda, Hiroto, Igaki, Makoto, Komatsu, Motoaki, Tanaka, Shin-ichiro

“…We aimed to evaluate the effect of moderate-intensity seated exercise on metabolic outcomes in hypertensive individuals with or without exercise habits…”
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The hydrolase DDAH2 enhances pancreatic insulin secretion by transcriptional regulation of secretagogin through a Sirt1‐dependent mechanism in mice by Hasegawa, Kazuhiro, Wakino, Shu, Kimoto, Masumi, Minakuchi, Hitoshi, Fujimura, Keiko, Hosoya, Koji, Komatsu, Motoaki, Kaneko, Yuka, Kanda, Takeshi, Tokuyama, Hirobumi, Hayashi, Koichi, Itoh, Hiroshi

“…The role of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in glucose metabolism is unknown. Here, we generated DDAH2 transgenic (Tg) mice. These mice had…”
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The role of adipose tissue asymmetric dimethylarginine/dimethylarginine dimethylaminohydrolase pathway in adipose tissue phenotype and metabolic abnormalities in subtotally nephrectomized rats by Minakuchi, Hitoshi, Wakino, Shu, Hosoya, Kozi, Sueyasu, Keiko, Hasegawa, Kazuhiro, Shinozuka, Keisuke, Yoshifuji, Ayumi, Futatsugi, Koji, Komatsu, Motoaki, Kanda, Takeshi, Tokuyama, Hirobumi, Hayashi, Koichi, Itoh, Hiroshi

“…The lipodystrophy-like phenotype has been suggested in early chronic kidney disease (CKD). It includes adipose tissue atrophy, systemic insulin resistance…”
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Cellular and Humoral Immune Responses after Breakthrough Infection in Patients Undergoing Hemodialysis by Toda, Masataro, Yoshifuji, Ayumi, Nakayama, Tetsuo, Mise-Omata, Setsuko, Oyama, Emi, Uwamino, Yoshifumi, Namkoong, Ho, Komatsu, Motoaki, Yoshimura, Akihiko, Hasegawa, Naoki, Kikuchi, Kan, Ryuzaki, Munekazu

“…Coronavirus disease 2019 (COVID-19) following primary immunization (breakthrough infection) has been reported in hemodialysis patients; however, their…”
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Seasonal variations on endothelium‐dependent flow‐mediated vasodilation in adults with type 2 diabetes and nondiabetic adults with hypertension and/or dyslipidaemia who perform regular exercise by Honda, Hiroto, Igaki, Makoto, Komatsu, Motoaki, Tanaka, Shin‐ichiro

“…Introduction Endothelium‐dependent flow‐mediated dilation (FMD) of the brachial artery often changes seasonally. We aimed to examine the association between…”
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Effect of maintaining supervised gym- and home-based exercises on the seasonal variations of metabolic outcomes in overweight and obese Japanese adults by Honda, Hiroto, Igaki, Makoto, Komatsu, Motoaki, Tanaka, Shin-ichiro

“…ObjectivesThis study aimed to examine whether maintaining supervised gym- and home-based exercises for an extended time of period could decrease seasonal…”
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