Search Results - "Komatsu, Katsuichiro"

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    Inhibition of bacterial undecaprenyl pyrophosphate synthase by small fungal molecules by Inokoshi, Junji, Nakamura, Yuichiro, Komada, Saori, Komatsu, Katsuichiro, Umeyama, Hideaki, Tomoda, Hiroshi

    Published in Journal of antibiotics (01-11-2016)
    “…Viridicatumtoxin and spirohexaline, small fungal molecules with a tetracyclic scaffold and an additional spirobicyclic ring in common, were found to inhibit…”
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  3. 3

    Evaluation of the third solvent clusters fitting procedure for the prediction of protein-protein interactions based on the results at the CAPRI blind docking study by Komatsu, Katsuichiro, Kurihara, Youji, Iwadate, Mitsuo, Takeda-Shitaka, Mayuko, Umeyama, Hideaki

    “…To predict protein–protein interactions, rough or coarse handling for the induced fit problem is proposed. Our method involves the overlap of two hydrophobic…”
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    Regioselective Synthesis of 14-Membered Biaryl Ethers : Total Synthesis of RA-VII and Deoxybouvardin by INOUE, Tsutomu, INABA, Takashi, UMEZAWA, Isao, YUASA, Masayuki, ITOKAWA, Hideji, OGURA, Katsuyuki, KOMATSU, Katsuichiro, HARA, Hiroshi, HOSHINO, Osamu

    “…In order to obtain a key compound (22a") for synthesis of RA-VII (1) and deoxybouvardin (2), construction of the 14-membered ring system was performed by means…”
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    Electrostatic complementarities between guest ligands and host enzymes by NAKAMURA, H, KOMATSU, K, UMEYAMA, H

    Published in Journal of the Physical Society of Japan (01-01-1985)
    “…A method is described for visualizing electrostatic complementarity between a guest ligand and a host enzyme by using molecular graphics and drawing a…”
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  7. 7

    van der Waals Volume and the Related Parameters for Hydrophobicity in Structure-Activity Studies by MORIGUCHI, IKUO, KANADA, YAYOI, KOMATSU, KATSUICHIRO

    “…The correlations of Hansch's hydrophobic constant (log P) with van der Waals volume (Vw) and with van der Waals surface area (Aw) were studied using 60…”
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  8. 8

    Estimation of Hydrophobicity Based on the Solvent-Accessible Surface Area of Molecules by IWASE, KAZUHIKO, KOMATSU, KATSUICHIRO, HIRONO, SHUICHI, NAKAGAWA, SETSUKO, MORIGUCHI, IKUO

    Published in Chemical & pharmaceutical bulletin (01-01-1985)
    “…A novel method of estimating Hansch's hydrophobic constant (log P) by making use of the solvent-accessible surface area (SA) with correction for the…”
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  9. 9

    Searching for protein-protein interaction sites and docking by the methods of molecular dynamics, grid scoring, and the pairwise interaction potential of amino acid residues by Terashi, Genki, Takeda-Shitaka, Mayuko, Takaya, Daisuke, Komatsu, Katsuichiro, Umeyama, Hideaki

    “…In CAPRI Rounds 1 and 2, we assumed that because there are many ionic charges that weaken electrostatic interaction forces in living cells, the hydrophobic…”
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    ELECTROSTATIC FORCES IN THE INHIBITION OF DIHYDROFOLATE REDUCTASE BY METHOTREXATE. A FIELD POTENTIAL STUDY by Komatsu, Katsuichiro, Nakamura, Haruki, Nakagawa, Setsuko, Umeyama, Hideaki

    Published in Chemical & pharmaceutical bulletin (01-01-1984)
    “…Methotrexate (MTX) is a high affinity inhibitor of the reaction catalyzed by dihydrofolate reductase (DHFR) from Lactobacillus casei. MTX is a folic acid…”
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    Electrostatic Interaction Energy and Solvent Accessibility in the Methotrexate-Reduced Nicotinamide Adenine Dinucleotide Phosphate-Dihydrofolate Reductase Ternary Complex by KOMATSU, KATSUICHIRO, NAKAGAWA, SETSUKO, UMEYAMA, HIDEAKI, NAKAMURA, HARUKI

    “…The electrostatic interaction energies among dihydrofolate reductase (DHFR), coenzyme reduced nicotinamide adenine dinucleotide phosphate (NADPH) and…”
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    AQUATIC TOXICITY. : A PREDICTIVE STRUCTURE-ACTIVITY MODEL by Komatsu, Katsuichiro, Hirono, Shuichi, Moriguchi, Ikuo

    Published in Chemical & pharmaceutical bulletin (01-01-1985)
    “…A quantitative structure-toxicity model has been developed for the estimation of aquatic toxicity ratings for a wide variety of organic chemicals using the…”
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  13. 13

    Adaptive Least-Squares Classification applied to Structure-Activity Correlation of Antitumor Mitomycin Derivatives by MORIGUCHI, IKUO, KOMATSU, KATSUICHIRO

    “…An adaptive least-squares (ALS) classification which is capable of relating structure to activity rating of chemical compounds has been developed. The ALS…”
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    Regioselective Synthesis of 14-Membered Biaryl Ethers by INOUE, Tsutomu, INABA, Takashi, UMEZAWA, Isao, YUASA, Masayuki, ITOKAWA, Hideji, OGURA, Katsuyuki, KOMATSU, Katsuichiro, HARA, Hiroshi, HOSHINO, Osamu

    Published in Chemical & pharmaceutical bulletin (01-08-1995)
    “…In order to obtain a key compound (22a") for synthesis of RA-VII (1) and deoxybouvardin (2), construction of the 14-membered ring system was performed by means…”
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    Journal Article
  15. 15

    Adaptive least-squares method applied to structure-activity correlation of hypotensive N-alkyl-N''-cyano-N'-pyridylguanidines by Moriguchi, Ikuo, Komatsu, Katsuichiro, Matsushita, Yasuo

    Published in Journal of medicinal chemistry (01-01-1980)
    “…A method using an adaptive least-squares (ALS) technique has been developed for the discrimination of ordered categorical data. The method (ALS method) has the…”
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