Search Results - "Komarova, Nina I."

New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling by Salomatina, Oksana V, Kornienko, Tatyana E, Zakharenko, Alexandra L, Komarova, Nina I, Achara, Chigozie, Reynisson, Jóhannes, Salakhutdinov, Nariman F, Lavrik, Olga I, Volcho, Konstantin P

“…Deoxycholic acid derivatives containing various heterocyclic functional groups at C-3 on the steroid scaffold were designed and synthesized as promising dual…”
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Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo by Salomatina, Oksana V, Sen'kova, Aleksandra V, Moralev, Arseny D, Savin, Innokenty A, Komarova, Nina I, Salakhutdinov, Nariman F, Zenkova, Marina A, Markov, Andrey V

“…It is known that epoxide-bearing compounds display pronounced pharmacological activities, and the epoxidation of natural metabolites can be a promising…”
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Synthesis and In Vitro Study of Antiviral Activity of Glycyrrhizin Nicotinate Derivatives against HIV-1 Pseudoviruses and SARS-CoV-2 Viruses by Fomenko, Vladislav V, Rudometova, Nadezhda B, Yarovaya, Olga I, Rogachev, Artem D, Fando, Anastasia A, Zaykovskaya, Anna V, Komarova, Nina I, Shcherbakov, Dmitry N, Pyankov, Oleg V, Pokrovsky, Andrey G, Karpenko, Larisa I, Maksyutov, Rinat A, Salakhutdinov, Nariman F

“…When developing drugs against SARS-CoV-2, it is important to consider the characteristics of patients with different co-morbidities. People infected with HIV-1…”
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New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2 by Salomatina, Oksana V, Dyrkheeva, Nadezhda S, Popadyuk, Irina I, Zakharenko, Alexandra L, Ilina, Ekaterina S, Komarova, Nina I, Reynisson, Jóhannes, Salakhutdinov, Nariman F, Lavrik, Olga I, Volcho, Konstantin P

“…A series of deoxycholic acid (DCA) amides containing benzyl ether groups on the steroid core were tested against the tyrosyl-DNA phosphodiesterase 1 (TDP1) and…”
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Novel 3'-Substituted-1',2',4'-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O -Acylated Amidoximes: Synthesis and Evaluation of Antitumor and Anti-Inflammatory Potential In Vitro and In Vivo by Markov, Andrey V, Sen'kova, Aleksandra V, Popadyuk, Irina I, Salomatina, Oksana V, Logashenko, Evgeniya B, Komarova, Nina I, Ilyina, Anna A, Salakhutdinov, Nariman F, Zenkova, Marina A

“…A series of novel 18βH-glycyrrhetinic acid (GA) derivatives containing 3'-(alkyl/phenyl/pyridin(-2″, -3″, and -4″)-yl)-1',2',4'-oxadiazole moieties at the C-30…”
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Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors by Salomatina, Oksana V, Popadyuk, Irina I, Zakharenko, Alexandra L, Zakharova, Olga D, Fadeev, Dmitriy S, Komarova, Nina I, Reynisson, Jóhannes, Arabshahi, H John, Chand, Raina, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I

“…An Important task in the treatment of oncological and neurodegenerative diseases is the search for new inhibitors of DNA repair system enzymes. Tyrosyl-DNA…”
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Cardioprotective effect of resveratrol and resveratroloside by Naumenko, Sergey E, Latysheva, Tatiana V, Gilinsky, Michael A, Rogachev, Artem D, Komarova, Nina I, Salakhutdinov, Nariman F, Tolstikov, Genrikh A

“…Cardioprotective effect of resveratrol and resveratroloside was determined in ischemia-reperfusion experiments on rats. It was found that single…”
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Deoxycholic acid as a molecular scaffold for tyrosyl-DNA phosphodiesterase 1 inhibition: A synthesis, structure–activity relationship and molecular modeling study by Salomatina, Oksana V., Popadyuk, Irina I., Zakharenko, Alexandra L., Zakharova, Olga D., Chepanova, Arina A., Dyrkheeva, Nadezhda.S., Komarova, Nina I., Reynisson, Jóhannes, Anarbaev, Rashid O., Salakhutdinov, Nariman F., Lavrik, Olga I., Volcho, Konstantin P.

“…[Display omitted] •para-Bromoanilides of deoxycholic acid derivatives were designed and synthesized.•All target compounds were evaluated as inhibitors of…”
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Anti-viral activity of (−)- and (+)-usnic acids and their derivatives against influenza virus A(H1N1)2009 by Sokolov, Dmitriy N., Zarubaev, Vladimir V., Shtro, Anna A., Polovinka, Marina P., Luzina, Olga A., Komarova, Nina I., Salakhutdinov, Nariman F., Kiselev, Oleg I.

“…Influenza is a widespread respiratory infection. Every year it causes epidemics, quickly spreading from country to country, or even pandemics, involving a…”
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Diffractaic acid and its ethers as anti-respiratory syncytial virus agents by Filimonov, Aleksandr S., Ismangulova, Diana U., Diveikina, Anastasia A., Komarova, Nina I., Luzina, Olga A., Shtro, Anna A., Galochkina, Anastasia V., Nikolaeva, Yulia V., Klabukov, Artem M., Krivitskaya, Vera Z., Salakhutdinov, Nariman F.

“…A major secondary metabolite of lichens, diffractaic acid, was found here to exert a significant antiviral action on respiratory syncytial virus strain A2 with…”
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New type of anti-influenza agents based on benzo[d][1,3]dithiol core by Khomenko, Tatyana M., Zarubaev, Vladimir V., Kireeva, Marina V., Volobueva, Alexandrina S., Slita, Alexander V., Borisevich, Sophia S., Korchagina, Dina V., Komarova, Nina I., Volcho, Konstantin P., Salakhutdinov, Nariman F.

“…[Display omitted] We synthesized a series of amides with a benzo[d][1,3]dithiol core. The chemical library of compounds was tested for their cytotoxicity and…”
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Smiles rearrangements in a series of berberine analogues containing a secondary acetamide fragment by Nechepurenko, Ivan V., Komarova, Nina I., Shernyukov, Andrey V., Vasiliev, Vladimir G., Salakhutdinov, Nariman F.

“…[Display omitted] Smiles rearrangements occurring in the derivatives of the isoquinoline alkaloid, berberine, containing an oxyacetic acid fragment at C-9 are…”
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Cytotoxic and cancer preventive activity of benzotrithioles and benzotrithiole oxides, synthetic analogues of varacins by Kuzmich, Alexandra S., Khomenko, Tatyana M., Fedorov, Sergey N., Makarieva, Tatyana N., Shubina, Larisa K., Komarova, Nina I., Korchagina, Dina V., Rybalova, Tatyana V., Volcho, Konstantin P., Salakhutdinov, Nariman F.

“…The cytotoxic and cancer preventive activities of synthetic analogs of natural varacins with polysulfide groups were studied. Presence of a sulfoxide group was…”
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Synthesis of Nitrogen-Containing Derivatives of (18α,19β)-19-Hydroxy-2,3-secooleanane-2,3,28-trioic Acid 28,19-Lactone by Shernyukov, Andrey V., Mainagashev, Ilya Ya, Korchagina, Dina V., Genaev, Alexander M., Komarova, Nina I., Salakhutdinov, Nariman F., Tolstikov, Genrikh A.

“…The object of this study is the interaction of the cyclic anhydride 2 of (18α,19β)‐19‐hydroxy‐2,3‐secooleanane‐2,3,28‐trioic acid 28,19‐lactone (1) with…”
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Aryloxyacetamides Derived from Resveratroloside and Pinostilbenoside by Pozdeeva, Alexandra V., Komarova, Nina I., Vasiliev, Vladimir G., Rogachev, Artem D., Salakhutdinov, Nariman F., Tolstikov, Genrikh A.

“…Etherification of phenolic hydroxyl groups of resveratroloside and pinostilbenoside (natural 3,4’,5-trihydroxystilbene derivatives) with methyl bromoacetate…”
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Synthesis and activity of (+)-usnic acid and (−)-usnic acid derivatives containing 1,3-thiazole cycle against Mycobacterium tuberculosis by Bekker, Olga B., Sokolov, Dmitry N., Luzina, Olga A., Komarova, Nina I., Gatilov, Yuriy V., Andreevskaya, Sofia N., Smirnova, Tatiana G., Maslov, Dmitry A., Chernousova, Larisa N., Salakhutdinov, Nariman F., Danilenko, Valery. N.

“…New usnic acid (UA) derivatives were investigated in vitro to elucidate their potential inhibitory activities on the growth of Mycobacterium smegmatis and…”
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Long-lived reactive intermediate photogenerated from N-(5-azido-2-nitrobenzoyl)- N′-( d-biotinyl)-1,2-diaminoethane as an affinity reagent to streptavidin by Popova, Tatyana V, Yu. Denisov, Alexey, Shakirov, Makhmut M, Komarova, Nina I, Alekseyev, Pavel V, Serebriakova, Marina V, Godovikova, Tatyana S

“…Irradiation of a complex between N-(5-azido-2-nitrobenzoyl)- N′-( d-biotinyl)-1,2-diaminoethane ( I) and streptavidin with light of 313 nm led to the covalent…”
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Anti-viral activity of (―)- and (+)-usnic acids and their derivatives against influenza virus A(H1N1)2009 by SOKOLOV, Dmitriy N, ZARUBAEV, Vladimir V, SHTRO, Anna A, POLOVINKA, Marina P, LUZINA, Olga A, KOMAROVA, Nina I, SALAKHUTDINOV, Nariman F, KISELEV, Oleg I

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New chiral basic heterogeneous catalyst based on Csβ zeolite by Suslov, Evgeniy V., Korchagina, Dina V., Komarova, Nina I., Volcho, Konstantin P., Salakhutdinov, Nariman F.

“…A new basic chiral catalyst Met-Csβ has been synthesised for preparing optically active products of the Michael reaction and tandem transformations by the…”
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