Search Results - "Komarova, Ekaterina"
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Zn-, Cu- or Ag-incorporated micro-arc coatings on titanium alloys: Properties and behavior in synthetic biological media
Published in Surface & coatings technology (15-07-2019)“…Zn-, Cu- or Ag-incorporated calcium phosphate coatings were deposited on pure titanium and Ti-40 wt% Nb substrates by the micro-arc oxidation method…”
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2
Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome
Published in Journal of molecular biology (16-03-2018)“…Antibiotic chloramphenicol (CHL) binds with a moderate affinity at the peptidyl transferase center of the bacterial ribosome and inhibits peptide bond…”
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3
Comparative characteristics of the emissions control during the operation of passenger trains
Published in E3S Web of Conferences (01-01-2023)“…The trend in the development of railway transport also includes the solution of such an important environmental, technological, sanitary and, to some extent,…”
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4
Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel
Published in Nature chemical biology (01-10-2017)“…Identification of the antibiotic peptide KLB, from Klebsiella pneumoniae , which inhibits the growth of various Gram-negative bacteria by binding the nascent…”
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Biosynthesis of Translation Inhibitor Klebsazolicin Proceeds through Heterocyclization and N‑Terminal Amidine Formation Catalyzed by a Single YcaO Enzyme
Published in Journal of the American Chemical Society (25-04-2018)“…Klebsazolicin (KLB) is a recently discovered Klebsiella pneumonia peptide antibiotic targeting the exit tunnel of bacterial ribosome. KLB contains an…”
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6
Zn- or Cu-Containing CaP-Based Coatings Formed by Micro-arc Oxidation on Titanium and Ti-40Nb Alloy: Part I—Microstructure, Composition and Properties
Published in Materials (16-09-2020)“…Zn- and Cu-containing CaP-based coatings, obtained by micro-arc oxidation process, were deposited on substrates made of pure titanium (Ti) and novel Ti-40Nb…”
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7
Translation at first sight: the influence of leading codons
Published in Nucleic acids research (09-07-2020)“…Abstract First triplets of mRNA coding region affect the yield of translation. We have applied the flowseq method to analyze >30 000 variants of the codons…”
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Sorting Out Antibiotics' Mechanisms of Action: a Double Fluorescent Protein Reporter for High-Throughput Screening of Ribosome and DNA Biosynthesis Inhibitors
Published in Antimicrobial agents and chemotherapy (01-12-2016)“…In order to accelerate drug discovery, a simple, reliable, and cost-effective system for high-throughput identification of a potential antibiotic mechanism of…”
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9
Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel
Published in Nature chemical biology (01-10-2020)“…The increase in multi-drug resistant pathogenic bacteria is making our current arsenal of clinically used antibiotics obsolete, highlighting the urgent need…”
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10
Modification of titanium surface via Ag-, Sr- and Si-containing micro-arc calcium phosphate coating
Published in Bioactive materials (01-12-2019)“…The current research is devoted to the study of the modification of the titanium implants by the micro-arc oxidation with bioactive calcium phosphate coatings…”
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11
Flow-Seq Evaluation of Translation Driven by a Set of Natural Escherichia coli 5′-UTR of Variable Length
Published in International journal of molecular sciences (14-10-2022)“…Flow-seq is a method that combines fluorescently activated cell sorting and next-generation sequencing to deduce a large amount of data about translation…”
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12
Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome
Published in RNA (Cambridge) (01-06-2020)“…Macrolides are one of the most successful and widely used classes of antibacterials, which kill or stop the growth of pathogenic bacteria by binding near the…”
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13
Nybomycin-producing Streptomyces isolated from carpenter ant Camponotus vagus
Published in Biochimie (01-05-2019)“…A novel strain of Actinomycetes was isolated from the body of an ant (Camponotus vagus Scopoli) and its genetic and morphological properties were…”
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Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state
Published in Nucleic acids research (07-07-2017)“…The emergence of multi-drug resistant bacteria is limiting the effectiveness of commonly used antibiotics, which spurs a renewed interest in revisiting older…”
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Journal Article -
15
Application of sorting and next generation sequencing to study 5΄-UTR influence on translation efficiency in Escherichia coli
Published in Nucleic acids research (07-04-2017)“…Yield of protein per translated mRNA may vary by four orders of magnitude. Many studies analyzed the influence of mRNA features on the translation yield…”
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16
Enhanced Corrosion Resistance and Mechanical Durability of the Composite PLGA/CaP/Ti Scaffolds for Orthopedic Implants
Published in Polymers (15-03-2024)“…In addressing the challenge of enhancing orthopedic implants, 3D porous calcium phosphate (CaP) coatings on titanium (Ti) substrates modified with…”
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Characterization of the Micro-Arc Coatings Containing β-Tricalcium Phosphate Particles on Mg-0.8Ca Alloy
Published in Metals (Basel ) (01-04-2018)“…The characterization of the microstructure, morphology, topography, composition, and physical and chemical properties of the coatings containing β-tricalcium…”
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Influence of the spacer region between the Shine–Dalgarno box and the start codon for fine‐tuning of the translation efficiency in Escherichia coli
Published in Microbial biotechnology (01-07-2020)“…Summary Translation efficiency contributes several orders of magnitude difference in the overall yield of exogenous gene expression in bacteria. In diverse…”
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Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides
Published in Antimicrobial agents and chemotherapy (01-06-2019)“…Although macrolides are known as excellent antibacterials, their medical use has been significantly limited due to the spread of bacterial drug resistance…”
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20
Gene Expression Regulation and Secretory Activity of Mesenchymal Stem Cells upon In Vitro Contact with Microarc Calcium Phosphate Coating
Published in International journal of molecular sciences (16-10-2020)“…The manufacture of biomaterial surfaces with desired physical and chemical properties that can directly induce osteogenic differentiation without the need for…”
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