Search Results - "Komarova, Anastasia D."
-
1
Simultaneous Probing of Metabolism and Oxygenation of Tumors In Vivo Using FLIM of NAD(P)H and PLIM of a New Polymeric Ir(III) Oxygen Sensor
Published in International journal of molecular sciences (06-09-2022)“…Tumor cells are well adapted to grow in conditions of variable oxygen supply and hypoxia by switching between different metabolic pathways. However, the…”
Get full text
Journal Article -
2
Biocompatible Ir(III) Complexes as Oxygen Sensors for Phosphorescence Lifetime Imaging
Published in Molecules (Basel, Switzerland) (13-05-2021)“…Synthesis of biocompatible near infrared phosphorescent complexes and their application in bioimaging as triplet oxygen sensors in live systems are still…”
Get full text
Journal Article -
3
Red Light-Emitting Water-Soluble Luminescent Iridium-Containing Polynorbornenes: Synthesis, Characterization and Oxygen Sensing Properties in Biological Tissues In Vivo
Published in Molecules (Basel, Switzerland) (20-10-2021)“…New water-soluble polynorbornenes - containing oligoether, amino acid groups and luminophoric complexes of iridium(III) were synthesized by ring-opening…”
Get full text
Journal Article -
4
Biocompatible Phosphorescent O2 Sensors Based on Ir(III) Complexes for In Vivo Hypoxia Imaging
Published in Biosensors (Basel) (26-06-2023)“…In this work, we obtained three new phosphorescent iridium complexes (Ir1–Ir3) of general stoichiometry [Ir(N^C)2(N^N)]Cl decorated with oligo(ethylene glycol)…”
Get full text
Journal Article -
5
Phosphorescent O2-Probes Based on Ir(III) Complexes for Bioimaging Applications
Published in Chemosensors (28-04-2023)“…The design, synthesis, and investigation of new molecular oxygen probes for bioimaging, based on phosphorescent transition metal complexes are among the…”
Get full text
Journal Article -
6
Oxygen Assessment in Tumors In Vivo Using Phosphorescence Lifetime Imaging Microscopy
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…The oxygen level in a tumor is a crucial factor for its development and response to therapies. Phosphorescence lifetime imaging (PLIM) with the use of…”
Get more information
Journal Article -
7
Effects of Irinotecan on Tumor Vasculature and Oxygenation: An in vivo Study on Colorectal Cancer Model
Published in IEEE journal of selected topics in quantum electronics (01-07-2021)“…The effects of chemotherapy on the tumor microenvironment remain poorly investigated, although these are crucial for the drug delivery and anti-tumor activity…”
Get full text
Journal Article -
8
Dermatological toxicity in the treatment of malignant tumors in children: A review
Published in Sovremennaia onkologiia : zhurnal kafedry onkologii RMAPO dlia nepreryvnogo poslediplomnogo obrazovaniia (21-02-2024)“…Modern antitumor drugs have high antitumor activity. But only a number of them realize their antitumor effect in a targeted manner with minimal manifestations…”
Get full text
Journal Article -
9
Attenuation coefficient as a tool to detect changes in the white matter of the rat brain caused by different types of gliomas and irradiation
Published in Biomedical optics express (01-11-2024)“…In the present work, we carried out a comparative study of the attenuation coefficient of the white matter of the rat brain during the growth of glial tumors…”
Get full text
Journal Article -
10
Insights into metabolic heterogeneity of colorectal cancer gained from fluorescence lifetime imaging
Published in eLife (28-08-2024)“…Heterogeneity of tumor metabolism is an important, but still poorly understood aspect of tumor biology. Present work is focused on the visualization and…”
Get full text
Journal Article -
11
Multiphoton microscopy assessment of the structure and variability changes of dermal connective tissue in vulvar lichen sclerosus: A pilot study
Published in Journal of biophotonics (01-09-2022)“…In this article, we offer a novel classification of progressive changes in the connective tissue of dermis in vulvar lichen sclerosus (VLS) relying on…”
Get full text
Journal Article -
12
Phosphorescent cyclometalated iridium(III) complexes incorporated into polynorbornene polymeric platform as potential probes for assessments of oxygen in cancer cells
Published in Journal of organometallic chemistry (10-10-2024)“…•New polymeric iridium(III) complexes PnIr1-PnIr4 were synthesized by metathesis polymerization method.•Polymeric complexes PnIr1-PnIr4 demonstrated intense…”
Get full text
Journal Article -
13
Biocompatible Phosphorescent O[sub.2] Sensors Based on Ir Complexes for In Vivo Hypoxia Imaging
Published in Biosensors (Basel) (01-06-2023)“…In this work, we obtained three new phosphorescent iridium complexes (Ir1–Ir3) of general stoichiometry [Ir(N^C)[sub.2] (N^N)]Cl decorated with oligo(ethylene…”
Get full text
Journal Article -
14
Insights into metabolic heterogeneity of colorectal cancer gained from fluorescence lifetime imaging
Published in eLife (28-08-2024)“…Heterogeneity of tumor metabolism is an important, but still poorly understood aspect of tumor biology. Present work is focused on the visualization and…”
Get full text
Journal Article -
15
Biocompatible Phosphorescent O 2 Sensors Based on Ir(III) Complexes for In Vivo Hypoxia Imaging
Published in Biosensors (Basel) (26-06-2023)“…In this work, we obtained three new phosphorescent iridium complexes ( - ) of general stoichiometry [Ir(N^C) (N^N)]Cl decorated with oligo(ethylene glycol)…”
Get full text
Journal Article -
16
Phosphorescent O[sub.2]-Probes Based on Ir Complexes for Bioimaging Applications
Published in Chemosensors (01-04-2023)“…The design, synthesis, and investigation of new molecular oxygen probes for bioimaging, based on phosphorescent transition metal complexes are among the…”
Get full text
Journal Article