Search Results - "Komano, Yukiko"

Impact of the HLA-DRB1 shared epitope on responses to treatment with tofacitinib or abatacept in patients with rheumatoid arthritis by Hirose, Wataru, Harigai, Masayoshi, Amano, Koichi, Hidaka, Toshihiko, Itoh, Kenji, Aoki, Kazutoshi, Nakashima, Masahiro, Nagasawa, Hayato, Komano, Yukiko, Nanki, Toshihiro, Akiyama, Yuji, Ando, Souichirou, Hashiba, Yayoi, Kaneko, Motohide, Kawagoe, Mitsuhiro, Kondo, Tsuneo, Kubo, Kazuyoshi, Masuda, Ikuko, Matsumoto, Mitsuyo, Okada, Yusuke, Shibata, Akiko, Suzuki, Kimihiro, Takamatsu, Ko, Takei, Hirofumi

“…Abstract Objectives The aim of this study was to compare the clinical effectiveness of tofacitinib and abatacept and clarify the impact of the HLA-DRB1 shared…”
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Arthritic joint-targeting small interfering RNA-encapsulated liposome: implication for treatment strategy for rheumatoid arthritis by Komano, Yukiko, Yagi, Nobuhiro, Onoue, Ikumi, Kaneko, Kayoko, Miyasaka, Nobuyuki, Nanki, Toshihiro

“…RNA interference, mediated by small interfering RNA (siRNA), is effective in silencing genes with a high degree of specificity. To explore the therapeutic…”
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Risk for malignancy in rheumatoid arthritis patients treated with biological disease-modifying antirheumatic drugs compared to the general population: A nationwide cohort study in Japan by Harigai, Masayoshi, Nanki, Toshihiro, Koike, Ryuji, Tanaka, Michi, Watanabe-Imai, Kaori, Komano, Yukiko, Sakai, Ryoko, Yamazaki, Hayato, Koike, Takao, Miyasaka, Nobuyuki

“…Objectives: To investigate and compare the risk for malignancy in rheumatoid arthritis (RA) patients treated with biologics in Japan to the general population…”
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Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis by Nanki, Toshihiro, Takada, Kazuki, Komano, Yukiko, Morio, Tomohiro, Kanegane, Hirokazu, Nakajima, Atsuo, Lipsky, Peter E, Miyasaka, Nobuyuki

“…Accumulation of B cells in the rheumatoid arthritis (RA) synovium has been reported, and it has been thought that these cells might contribute to the…”
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Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab: a retrospective review and case–control study of 17 patients by Watanabe, Kaori, Sakai, Ryoko, Koike, Ryuji, Sakai, Fumikazu, Sugiyama, Haruhito, Tanaka, Michi, Komano, Yukiko, Akiyama, Yuji, Mimura, Toshihide, Kaneko, Motohide, Tokuda, Hitoshi, Iso, Takenobu, Motegi, Mitsuru, Ikeda, Kei, Nakajima, Hiroshi, Taki, Hirofumi, Kubota, Tetsuo, Kodama, Hirotaka, Sugii, Shoji, Kuroiwa, Takashi, Nawata, Yasushi, Shiozawa, Kazuko, Ogata, Atsushi, Sawada, Shigemasa, Matsukawa, Yoshihiro, Okazaki, Takahiro, Mukai, Masaya, Iwahashi, Mitsuhiro, Saito, Kazuyoshi, Tanaka, Yoshiya, Nanki, Toshihiro, Miyasaka, Nobuyuki, Harigai, Masayoshi

“…Abstract Objectives To investigate the clinical characteristics and risk factors of Pneumocystis jirovecii pneumonia (PCP) in rheumatoid arthritis (RA)…”
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Tacrolimus-induced pulmonary injury in rheumatoid arthritis patients by Koike, Ryuji, Tanaka, Michi, Komano, Yukiko, Sakai, Fumikazu, Sugiyama, Haruhito, Nanki, Toshihiro, Ide, Hiroshi, Jodo, Satoshi, Katayama, Kou, Matsushima, Hidekazu, Miwa, Yusuke, Morita, Koichi, Nakashima, Hiroshi, Nakamura, Hiroyuki, Natsumeda, Masamitsu, Sato, Yoshiko, Semba, Seitaro, Tateishi, Mutsuto, Miyasaka, Nobuyuki, Harigai, Masayoshi

“…Abstract Background Tacrolimus (TAC) was approved in Japan in 2005 for rheumatoid arthritis (RA) patients having inadequate response to other disease-modifying…”
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A case of Behçet's disease with widespread perforating enteric ulcers preceded by a long history of peripheral gangrene by Honne, Kyoko, Kohsaka, Hitoshi, Kaneko, Hideki, Komano, Yukiko, Nakanishi, Shoichi, Kitagawa, Masanobu, Miyasaka, Nobuyuki

“…Abstract Patients suffering from Behçet's disease (BD) with intestinal involvement often have an atypical disease course. The disease in many patients does not…”
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Pneumocystis jirovecii pneumonia associated with etanercept treatment in patients with rheumatoid arthritis: a retrospective review of 15 cases and analysis of risk factors by Tanaka, Michi, Sakai, Ryoko, Koike, Ryuji, Komano, Yukiko, Nanki, Toshihiro, Sakai, Fumikazu, Sugiyama, Haruhito, Matsushima, Hidekazu, Kojima, Toshihisa, Ohta, Shuji, Ishibe, Yoji, Sawabe, Takuya, Ota, Yasuhiro, Ohishi, Kazuhisa, Miyazato, Hajime, Nonomura, Yoshinori, Saito, Kazuyoshi, Tanaka, Yoshiya, Nagasawa, Hayato, Takeuchi, Tsutomu, Nakajima, Ayako, Ohtsubo, Hideo, Onishi, Makoto, Goto, Yoshinori, Dobashi, Hiroaki, Miyasaka, Nobuyuki, Harigai, Masayoshi

“…Abstract Objectives The association of anti-tumor necrosis factor therapy with opportunistic infections in rheumatoid arthritis (RA) patients has been…”
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Reevaluation of antibody titers 1 year after influenza vaccination in patients with rheumatoid arthritis receiving TNF blockers by Nii, Tokiko, Kubota, Tetsuo, Nanki, Toshihiro, Komano, Yukiko, Harigai, Masayoshi, Kohsaka, Hitoshi, Hirose, Wataru, Nagasaka, Kenji, Sakurai, Tetsushi, Miyasaka, Nobuyuki

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The REAL database reveals no significant risk of serious infection during treatment with a methotrexate dose of more than 8 mg/week in patients with rheumatoid arthritis by Sakai, Ryoko, Komano, Yukiko, Tanaka, Michi, Nanki, Toshihiro, Koike, Ryuji, Nakajima, Atsuo, Atsumi, Tatsuya, Yasuda, Shinsuke, Tanaka, Yoshiya, Saito, Kazuyoshi, Tohma, Shigeto, Fujii, Takao, Ihata, Atsushi, Tamura, Naoto, Kawakami, Atsushi, Sugihara, Takahiko, Ito, Satoshi, Miyasaka, Nobuyuki, Harigai, Masayoshi

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Anti-tumor necrosis factor therapy does not diminish the immune response to influenza vaccine in Japanese patients with rheumatoid arthritis by Kubota, Tetsuo, Nii, Tokiko, Nanki, Toshihiro, Kohsaka, Hitoshi, Harigai, Masayoshi, Komano, Yukiko, Sugihara, Takahiko, Nonomura, Yoshinori, Hirose, Wataru, Nagasaka, Kenji, Sakurai, Tetsushi, Miyasaka, Nobuyuki

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A case of paraneoplastic syndrome mimicking adult-onset Still's disease by Komano, Yukiko, Kubota, Tetsuo, Wakabayashi, Shihoko, Ochi, Sae, Nonomura, Yoshinori, Hagiyama, Hiroyuki, Nanki, Toshihiro, Kohsaka, Hitoshi, Miyasaka, Nobuyuki

“…Abstract A 49-year-old woman was admitted to our hospital because of fever of unknown origin. The patient had long-lasting spiking fever, hepatosplenomegaly,…”
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Incidence and Risk Factors for Serious Infection in Patients with Rheumatoid Arthritis Treated with Tumor Necrosis Factor Inhibitors: A Report from the Registry of Japanese Rheumatoid Arthritis Patients for Longterm Safety by KOMANO, Yukiko, TANAKA, Michi, TOHMA, Shigeto, ITO, Satoshi, TAMURA, Naoto, FUJII, Takao, SAWADA, Tetsuji, IDA, Hiroaki, HASHIRAMOTO, Akira, KOIKE, Takao, ISHIGATSUBO, Yoshiaki, EGUCHI, Katsumi, NANKI, Toshihiro, TANAKA, Yoshiya, TAKEUCHI, Tsutomu, MIYASAKA, Nobuyuki, HARIGAI, Masayoshi, KOIKE, Ryuji, SAKAI, Ryoko, KAMEDA, Hideto, NAKAJIMA, Atsuo, SAITO, Kazuyoshi, TAKENO, Mitsuhiro, ATSUMI, Tatsuya

“…To compare tumor necrosis factor-α (TNF-α) inhibitors to nonbiological disease-modifying antirheumatic drugs (DMARD) for the risk of serious infection in…”
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Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts by Komano, Yukiko, Nanki, Toshihiro, Hayashida, Kenji, Taniguchi, Ken, Miyasaka, Nobuyuki

“…Increased bone resorption mediated by osteoclasts causes various diseases such as osteoporosis and bone erosion in rheumatoid arthritis (RA). Osteoclasts are…”
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Real-world effectiveness and safety of tofacitinib and abatacept in patients with rheumatoid arthritis by Hirose, Wataru, Harigai, Masayoshi, Amano, Koichi, Hidaka, Toshihiko, Itoh, Kenji, Aoki, Kazutoshi, Nakashima, Masahiro, Nagasawa, Hayato, Komano, Yukiko, Nanki, Toshihiro

“…Abstract Objective We compared the 52-week effectiveness and safety of tofacitinib (TOF) and abatacept (ABT) in patients with RA in a real-world setting and…”
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Time‐dependent increased risk for serious infection from continuous use of tumor necrosis factor antagonists over three years in patients with rheumatoid arthritis by Sakai, Ryoko, Komano, Yukiko, Tanaka, Michi, Nanki, Toshihiro, Koike, Ryuji, Nagasawa, Hayato, Amano, Koichi, Nakajima, Atsuo, Atsumi, Tatsuya, Koike, Takao, Ihata, Atsushi, Ishigatsubo, Yoshiaki, Saito, Kazuyoshi, Tanaka, Yoshiya, Ito, Satoshi, Sumida, Takayuki, Tohma, Shigeto, Tamura, Naoto, Fujii, Takao, Sugihara, Takahiko, Kawakami, Atsushi, Hagino, Noboru, Ueki, Yukitaka, Hashiramoto, Akira, Nagasaka, Kenji, Miyasaka, Nobuyuki, Harigai, Masayoshi

“…Objective To investigate associations between continuous treatments with tumor necrosis factor (TNF) antagonists and risk for developing serious infections…”
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Abatacept is Efficacious in the Treatment of Older Patients with csDMARD-Refractory Rheumatoid Arthritis: A Prospective, Multicenter, Observational Study by Muraoka, Sei, Yamada, Zento, Kawazoe, Mai, Hirose, Wataru, Kono, Hajime, Yasuda, Shinsuke, Komano, Yukiko, Kawano, Hiroshi, Hidaka, Toshihiko, Nakashima, Shusaku, Kasama, Tsuyoshi, Teramoto, Tamio, Nanki, Toshihiro

“…Introduction Abatacept efficacy in older patients with rheumatoid arthritis (RA) has been primarily demonstrated via retrospective comparisons with younger…”
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Pneumocystis jirovecii pneumonia associated with etanercept treatment in patients with rheumatoid arthritis: a retrospective review of 15 cases and analysis of risk factors by Tanaka, Michi, Sakai, Ryoko, Koike, Ryuji, Komano, Yukiko, Nanki, Toshihiro, Sakai, Fumikazu, Sugiyama, Haruhito, Matsushima, Hidekazu, Kojima, Toshihisa, Ohta, Shuji, Ishibe, Yoji, Sawabe, Takuya, Ota, Yasuhiro, Ohishi, Kazuhisa, Miyazato, Hajime, Nonomura, Yoshinori, Saito, Kazuyoshi, Tanaka, Yoshiya, Nagasawa, Hayato, Takeuchi, Tsutomu, Nakajima, Ayako, Ohtsubo, Hideo, Onishi, Makoto, Goto, Yoshinori, Dobashi, Hiroaki, Miyasaka, Nobuyuki, Harigai, Masayoshi

“…Objectives The association of anti-tumor necrosis factor therapy with opportunistic infections in rheumatoid arthritis (RA) patients has been reported. The…”
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Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab: a retrospective review and case–control study of 17 patients by Watanabe, Kaori, Sakai, Ryoko, Koike, Ryuji, Sakai, Fumikazu, Sugiyama, Haruhito, Tanaka, Michi, Komano, Yukiko, Akiyama, Yuji, Mimura, Toshihide, Kaneko, Motohide, Tokuda, Hitoshi, Iso, Takenobu, Motegi, Mitsuru, Ikeda, Kei, Nakajima, Hiroshi, Taki, Hirofumi, Kubota, Tetsuo, Kodama, Hirotaka, Sugii, Shoji, Kuroiwa, Takashi, Nawata, Yasushi, Shiozawa, Kazuko, Ogata, Atsushi, Sawada, Shigemasa, Matsukawa, Yoshihiro, Okazaki, Takahiro, Mukai, Masaya, Iwahashi, Mitsuhiro, Saito, Kazuyoshi, Tanaka, Yoshiya, Nanki, Toshihiro, Miyasaka, Nobuyuki, Harigai, Masayoshi

“…Objectives To investigate the clinical characteristics and risk factors of Pneumocystis jirovecii pneumonia (PCP) in rheumatoid arthritis (RA) patients treated…”
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NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor by Kubota, Tetsuo, Hoshino, Machiko, Aoki, Kazuhiro, Ohya, Keiichi, Komano, Yukiko, Nanki, Toshihiro, Miyasaka, Nobuyuki, Umezawa, Kazuo

“…Abstract Inhibition of NF-κB is known to be effective in reducing both inflammation and bone destruction in animal models of arthritis. Our previous study…”
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