Search Results - "Komai, Kyoko"

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1 by Shichita, Takashi, Ito, Minako, Morita, Rimpei, Komai, Kyoko, Noguchi, Yoshiko, Ooboshi, Hiroaki, Koshida, Ryusuke, Takahashi, Satoru, Kodama, Tatsuhiko, Yoshimura, Akihiko

“…The scavenger receptor MSR1 contributes to the clearance of damage-associated molecular patterns (DAMPs) by infiltrating myeloid cells in the post-stroke…”
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Tissue regulatory T cells and neural repair by Ito, Minako, Komai, Kyoko, Nakamura, Toshihiro, Srirat, Tanakorn, Yoshimura, Akihiko

“…Abstract Inflammation and immune responses after tissue injury play pivotal roles in the pathology, resolution of inflammation, tissue recovery, fibrosis and…”
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Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation by Komai, Kyoko, Shichita, Takashi, Ito, Minako, Kanamori, Mitsuhiro, Chikuma, Shunsuke, Yoshimura, Akihiko

“…Damage-associated molecular patterns (DAMPs) have been implicated in sterile inflammation in various tissue injuries. High-mobility group box 1 (HMGB1) is a…”
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Kidney GATA3+ regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury by Sakai, Ryota, Ito, Minako, Komai, Kyoko, Iizuka-Koga, Mana, Matsuo, Kazuhiko, Nakayama, Takashi, Yoshie, Osamu, Amano, Koichi, Nishimasu, Hiroshi, Nureki, Osamu, Kubo, Masato, Yoshimura, Akihiko

“…FoxP3 + regulatory T cells (Tregs) play crucial roles in peripheral immune tolerance. In addition, Tregs that reside or accumulate in nonlymphoid tissues,…”
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The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential by Mori, Hiroyuki, Inoki, Ken, Masutani, Kohsuke, Wakabayashi, Yu, Komai, Kyoko, Nakagawa, Ryusuke, Guan, Kun-Liang, Yoshimura, Akihiko

“…Diabetic nephropathy (DN) associated with type 2 diabetes is the most common cause of end-stage renal disease (ESRD) and a serious health issue in the world…”
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The Role of Ferroptosis in Adverse Left Ventricular Remodeling Following Acute Myocardial Infarction by Komai, Kyoko, Kawasaki, Nicholas K, Higa, Jason K, Matsui, Takashi

“…Ferroptosis is an iron-dependent form of regulated cell death and is distinct from other conventional forms of regulated cell death. It is often characterized…”
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Regulatory T Cells: Pathophysiological Roles and Clinical Applications by Sakai, Ryota, Komai, Kyoko, Iizuka-koga, Mana, Yoshimura, Akihiko, Ito, Minako

“…Inflammation and immune responses after tissue injury play pivotal roles in the resolution of inflammation, tissue recovery, fibrosis, and remodeling…”
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Single-Cell Analysis Revealed the Role of CD8 + Effector T Cells in Preventing Cardioprotective Macrophage Differentiation in the Early Phase of Heart Failure by Komai, Kyoko, Ito, Minako, Nomura, Seitaro, Shichino, Shigeyuki, Katoh, Manami, Yamada, Shintaro, Ko, Toshiyuki, Iizuka-Koga, Mana, Nakatsukasa, Hiroko, Yoshimura, Akihiko

“…Heart failure is a complex clinical syndrome characterized by insufficient cardiac function. Heart-resident and infiltrated macrophages have been shown to play…”
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Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance by Yoshimura, Akihiko, Chinen, Takatoshi, Komai, Kyoko, Muto, Go, Morita, Rimpei, Inoue, Naoko, Yoshida, Hideyuki, Sekiya, Takashi, Yoshida, Ryoko, Nakamura, Kazuhiko, Takayanagi, Ryoichi

“…Interleukin 10 (IL-10) and regulatory T cells (Tregs) maintain tolerance to intestinal microorganisms. However, Il10 −/− Rag2 −/− mice, which lack IL-10 and…”
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Gfi1 negatively regulates Th17 differentiation by inhibiting RORγt activity by Ichiyama, Kenji, Hashimoto, Masayuki, Sekiya, Takashi, Nakagawa, Ryusuke, Wakabayashi, Yu, Sugiyama, Yuki, Komai, Kyoko, Saba, Ingrid, Möröy, Tarik, Yoshimura, Akihiko

“…Th cells have long been divided into two subsets, Th1 and Th2; however, recently, Th17 and inducible regulatory T (iTreg) cells were identified as new Th cell…”
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Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery by Ito, Minako, Komai, Kyoko, Mise-Omata, Setsuko, Iizuka-Koga, Mana, Noguchi, Yoshiko, Kondo, Taisuke, Sakai, Ryota, Matsuo, Kazuhiko, Nakayama, Takashi, Yoshie, Osamu, Nakatsukasa, Hiroko, Chikuma, Shunsuke, Shichita, Takashi, Yoshimura, Akihiko

“…In addition to maintaining immune tolerance, FOXP3 + regulatory T (T reg ) cells perform specialized functions in tissue homeostasis and remodelling 1 , 2 …”
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Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells by Kashiwagi, Ikkou, Morita, Rimpei, Schichita, Takashi, Komai, Kyoko, Saeki, Keita, Matsumoto, Makoto, Takeda, Kiyoshi, Nomura, Masatoshi, Hayashi, Atsushi, Kanai, Takanori, Yoshimura, Akihiko

“…Colonization with a mixture of Clostridium species has been shown to induce accumulation of induced regulatory T (iTreg) cells in the colon. Transforming…”
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Reconstruction of Sjögren's syndrome-like sialadenitis by a defined disease specific gut-reactive single TCR and an autoantibody by Iizuka-Koga, Mana, Ito, Minako, Yumoto, Noriko, Mise-Omata, Setsuko, Hayakawa, Taeko, Komai, Kyoko, Chikuma, Shunsuke, Takahashi, Satoru, Matsumoto, Isao, Sumida, Takayuki, Yoshimura, Akihiko

“…Lymphocytes such as CD4+ T cells and B cells mainly infiltrate the salivary glands; however, the precise roles and targets of autoreactive T cells and…”
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The role of ferroptosis in cell-to-cell propagation of cell deathinitiated from focal injury in cardiomyocytes by Kawasaki, Nicholas K., Suhara, Tomohiro, Komai, Kyoko, Shimada, Briana K., Yorichika, Naaiko, Kobayashi, Motoi, Baba, Yuichi, Higa, Jason K., Matsui, Takashi

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The role of ferroptosis in cell-to-cell propagation of cell death initiated from focal injury in cardiomyocytes by Kawasaki, Nicholas K., Suhara, Tomohiro, Komai, Kyoko, Shimada, Briana K., Yorichika, Naaiko, Kobayashi, Motoi, Baba, Yuichi, Higa, Jason K., Matsui, Takashi

“…Ferroptosis has grown in importance as a key factor in ischemia-reperfusion (I/R) injury. This study explores the mechanism underlying fibrotic scarring…”
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Regulatory T Cells: Pathophysiological Roles and Clinical Applications by Sakai, Ryota, Komai, Kyoko, Iizuka-koga, Mana, Yoshimura, Akihiko, Ito, Minako

“…Inflammation and immune responses after tissue injury play pivotal roles in the resolution of inflammation, tissue recovery, fibrosis, and remodeling…”
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SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis by Nakaya, Mako, Hashimoto, Masayuki, Nakagawa, Ryusuke, Wakabayashi, Yu, Ishizaki, Takuma, Takada, Ichiro, Komai, Kyoko, Yoshida, Hiroki, Yoshimura, Akihiko

“…Suppressor of cytokine signaling 3 (SOCS3), a negative-feedback molecule for cytokine signaling, has been implicated in protection against liver injury…”
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Smad2 and Smad3 Inversely Regulate TGF-[beta] Autoinduction in Clostridium butyricum -Activated Dendritic Cells by Kashiwagi, Ikkou, Morita, Rimpei, Schichita, Takashi, Komai, Kyoko, Saeki, Keita, Matsumoto, Makoto, Takeda, Kiyoshi, Nomura, Masatoshi, Hayashi, Atsushi, Kanai, Takanori, Yoshimura, Akihiko

“…Colonization with a mixture ofClostridiumspecies has been shown to induce accumulation of induced regulatory T (iTreg) cells in the colon. Transforming growth…”
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Gfi1 negatively regulates T[sub]h17 differentiation by inhibiting ROR[gamma]t activity by Ichiyama, Kenji, Hashimoto, Masayuki, Sekiya, Takashi, Nakagawa, Ryusuke, Wakabayashi, Yu, Sugiyama, Yuki, Komai, Kyoko, Saba, Ingrid, Möröy, Tarik, Yoshimura, Akihiko

“…T[sub]h cells have long been divided into two subsets, T[sub]h1 and T[sub]h2; however, recently, T[sub]h17 and inducible regulatory T (iTreg) cells were…”
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Gfi1 negatively regulates T(h)17 differentiation by inhibiting RORgammat activity by Ichiyama, Kenji, Hashimoto, Masayuki, Sekiya, Takashi, Nakagawa, Ryusuke, Wakabayashi, Yu, Sugiyama, Yuki, Komai, Kyoko, Saba, Ingrid, Möröy, Tarik, Yoshimura, Akihiko

“…T(h) cells have long been divided into two subsets, T(h)1 and T(h)2; however, recently, T(h)17 and inducible regulatory T (iTreg) cells were identified as new…”
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