Search Results - "Koltsova, Ekaterina M."
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Urokinase-Conjugated Magnetite Nanoparticles as a Promising Drug Delivery System for Targeted Thrombolysis: Synthesis and Preclinical Evaluation
Published in ACS applied materials & interfaces (31-10-2018)“…Mortality and disabilities as outcomes of cardiovascular diseases are primarily related to blood clotting. Optimization of thrombolytic drugs is aimed at the…”
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Hypercoagulation detected by routine and global laboratory hemostasis assays in patients with infective endocarditis
Published in PloS one (15-12-2021)“…Coagulation system is heavily involved into the process of infective endocarditis (IE) vegetation formation and can facilitate further embolization. In this…”
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Thrombodynamics-A new global hemostasis assay for heparin monitoring in patients under the anticoagulant treatment
Published in PloS one (28-06-2018)“…Heparin therapy and prophylaxis may be accompanied by bleeding and thrombotic complications due to individual responses to treatment. Dosage control based on…”
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Hematin- and Hemin-Induced Spherization and Hemolysis of Human Erythrocytes Are Independent of Extracellular Calcium Concentration
Published in Cells (Basel, Switzerland) (01-03-2024)“…Pathologies such as malaria, hemorrhagic stroke, sickle cell disease, and thalassemia are characterized by the release of hemoglobin degradation products from…”
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Determination of fibrin clot growth and spatial thrombin propagation in the presence of different types of phospholipid surfaces
Published in Platelets (Edinburgh) (17-11-2021)“…In this work, we present a new method-Thrombodynamics-4D-for the assessment of both plasma and platelet contributions to clotting. Thrombodynamics-4D…”
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Comparison of standard and global hemostasis assays in cord and peripheral blood of newborns
Published in Pediatric research (17-08-2024)“…Umbilical cord blood is used for the testing of various parameters in newborns. However, data on its applicability for hemostasis assays is insufficient. To…”
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Platelets provide robustness of spatial blood coagulation to the variation of initial conditions
Published in Thrombosis research (01-10-2023)“…Activated platelets provide phospholipid surface and secrete coagulation factors, enhancing blood clotting. We investigated the role of platelets in the…”
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Impaired platelet activity and hypercoagulation in healthy term and moderately preterm newborns during the early neonatal period
Published in Pediatric research (01-01-2019)“…Background Preterm newborns are at thrombohemorrhagic risk during the early neonatal period. Taking into account the lack of informative tools for the…”
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Classic and Global Hemostasis Testing in Pregnancy and during Pregnancy Complications
Published in Seminars in thrombosis and hemostasis (01-10-2016)“…Pregnancy is associated with a significant procoagulant shift in the hemostatic system balance as well as other metabolic changes. Pregnancy can thereby…”
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The laboratory control of anticoagulant thromboprophylaxis during the early postpartum period after cesarean delivery
Published in Journal of perinatal medicine (25-04-2018)“…The incidence of venous thromboembolism (VTE) after cesarean section is up to 0.6%, and the widespread use of cesarean section draws attention to this group…”
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Platelet functional abnormalities in pediatric patients with kaposiform hemangioendothelioma/Kasabach-Merritt phenomenon
Published in Blood advances (12-09-2023)“…•We examined 13 patients with KHE, a rare vascular tumor with thrombocytopenia and coagulation dysfunction.•Platelet CLEC-2 and GPVI-induced activation is…”
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Mycophenolate Mofetil Decreases Atherosclerotic Lesion Size by Depression of Aortic T-Lymphocyte and Interleukin-17–Mediated Macrophage Accumulation
Published in Journal of the American College of Cardiology (24-05-2011)“…Objectives This study tested whether immunosuppression with mycophenolate mofetil (MMF) inhibits atherosclerosis development in apolipoprotein-E–deficient (…”
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