Search Results - "Kolter, Julia"

Origin and Differentiation of Nerve-Associated Macrophages by Kolter, Julia, Kierdorf, Katrin, Henneke, Philipp

“…The mature peripheral nervous system is a steady network structure yet shows remarkable regenerative properties. The interaction of peripheral nerves with…”
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From Flies to Men: ROS and the NADPH Oxidase in Phagocytes by Moghadam, Zohreh Mansoori, Henneke, Philipp, Kolter, Julia

“…The cellular formation of reactive oxygen species (ROS) represents an evolutionary ancient antimicrobial defense system against microorganisms. The NADPH…”
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Codevelopment of Microbiota and Innate Immunity and the Risk for Group B Streptococcal Disease by Kolter, Julia, Henneke, Philipp

“…The pathogenesis of neonatal late-onset sepsis (LOD), which manifests between the third day and the third month of life, remains poorly understood. Group B…”
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A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves by Kolter, Julia, Feuerstein, Reinhild, Zeis, Patrice, Hagemeyer, Nora, Paterson, Neil, d’Errico, Paolo, Baasch, Sebastian, Amann, Lukas, Masuda, Takahiro, Lösslein, Anne, Gharun, Kourosh, Meyer-Luehmann, Melanie, Waskow, Claudia, Franzke, Claus-Werner, Grün, Dominic, Lämmermann, Tim, Prinz, Marco, Henneke, Philipp

“…The skin comprises tissue macrophages as the most abundant resident immune cell type. Their diverse tasks including resistance against invading pathogens,…”
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Neonatal immune challenge poses a sex-specific risk for epigenetic microglial reprogramming and behavioral impairment by Schwabenland, Marius, Mossad, Omar, Sievert, Annika, Peres, Adam G., Ringel, Elena, Baasch, Sebastian, Kolter, Julia, Cascone, Giulia, Dokalis, Nikolaos, Vlachos, Andreas, Ruzsics, Zsolt, Henneke, Philipp, Prinz, Marco, Blank, Thomas

“…While the precise processes underlying a sex bias in the development of central nervous system (CNS) disorders are unknown, there is growing evidence that an…”
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Resident macrophages acquire innate immune memory in staphylococcal skin infection by Feuerstein, Reinhild, Forde, Aaron James, Lohrmann, Florens, Kolter, Julia, Ramirez, Neftali Jose, Zimmermann, Jakob, Gomez de Agüero, Mercedes, Henneke, Philipp

“…is a common colonizer of healthy skin and mucous membranes. At the same time, is the most frequent cause of skin and soft tissue infections. Dermal macrophages…”
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Monocyte progenitors give rise to multinucleated giant cells by Lösslein, Anne Kathrin, Lohrmann, Florens, Scheuermann, Lisa, Gharun, Kourosh, Neuber, Jana, Kolter, Julia, Forde, Aaron James, Kleimeyer, Christian, Poh, Ying Yee, Mack, Matthias, Triantafyllopoulou, Antigoni, Dunlap, Micah D., Khader, Shabaana A., Seidl, Maximilian, Hölscher, Alexandra, Hölscher, Christoph, Guan, Xue Li, Dorhoi, Anca, Henneke, Philipp

“…The immune response to mycobacteria is characterized by granuloma formation, which features multinucleated giant cells as a unique macrophage type. We…”
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Modeling MyD88 Deficiency In Vitro Provides New Insights in Its Function by Craig-Mueller, Nils, Hammad, Ruba, Elling, Roland, Alzubi, Jamal, Timm, Barbara, Kolter, Julia, Knelangen, Nele, Bednarski, Christien, Gläser, Birgitta, Ammann, Sandra, Ivics, Zoltán, Fischer, Judith, Speckmann, Carsten, Schwarz, Klaus, Lachmann, Nico, Ehl, Stephan, Moritz, Thomas, Henneke, Philipp, Cathomen, Toni

“…Inherited defects in MyD88 and IRAK4, two regulators in Toll-like receptor (TLR) signaling, are clinically highly relevant, but still incompletely understood…”
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Isolation and Flow Cytometry Analysis of Macrophages from the Dermis by Forde, Aaron James, Kolter, Julia

“…The dermis contains a dense network of tissue macrophages, which contribute to tissue homeostasis, inflammation, and pathogen clearance. Dermal macrophages are…”
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The role of CNS macrophages in streptococcal meningoencephalitis by Gres, Vitka, Kolter, Julia, Erny, Daniel, Henneke, Philipp

“…In the healthy brain, microglia and other CNS macrophages are the most abundant immune cell type. Thus, they form the natural immune cell interface with…”
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Dynamic interactions between dermal macrophages and Staphylococcus aureus by Feuerstein, Reinhild, Kolter, Julia, Henneke, Philipp

“…The dermis, a major reservoir of immune cells in immediate vicinity to the colonizing skin microflora, serves as an important site of host‐pathogen…”
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Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology by Kolter, Julia, Henneke, Philipp, Groß, Olaf, Kierdorf, Katrin, Prinz, Marco, Graf, Laura, Schwemmle, Martin

“…Innate immunity facilitates immediate defense against invading pathogens throughout all organs and tissues but also mediates tissue homeostasis and repair,…”
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2020 German Society for Immunology Prizes

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Cytomegalovirus subverts macrophage identity by Baasch, Sebastian, Giansanti, Piero, Kolter, Julia, Riedl, André, Forde, Aaron James, Runge, Solveig, Zenke, Simon, Elling, Roland, Halenius, Anne, Brabletz, Simone, Hengel, Hartmut, Kuster, Bernhard, Brabletz, Thomas, Cicin-Sain, Luka, Arens, Ramon, Vlachos, Andreas, Rohr, Jan Christopher, Stemmler, Marc Philippe, Kopf, Manfred, Ruzsics, Zsolt, Henneke, Philipp

“…Cytomegaloviruses (CMVs) have co-evolved with their mammalian hosts for millions of years, leading to remarkable host specificity and high infection…”
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Cytoplasmic replication of Staphylococcus aureus upon phagosomal escape triggered by phenol‐soluble modulin α by Grosz, Magdalena, Kolter, Julia, Paprotka, Kerstin, Winkler, Ann‐Cathrin, Schäfer, Daniel, Chatterjee, Som Subra, Geiger, Tobias, Wolz, Christiane, Ohlsen, Knut, Otto, Michael, Rudel, Thomas, Sinha, Bhanu, Fraunholz, Martin

“…Summary Staphylococcus aureus is a Gram‐positive human pathogen that is readily internalized by professional phagocytes such as macrophages and neutrophils but…”
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Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA by Krüger, Anne, Oldenburg, Marina, Chebrolu, Chiranjeevi, Beisser, Daniela, Kolter, Julia, Sigmund, Anna M, Steinmann, Jörg, Schäfer, Simon, Hochrein, Hubertus, Rahmann, Sven, Wagner, Hermann, Henneke, Philipp, Hornung, Veit, Buer, Jan, Kirschning, Carsten J

“…Toll‐like receptor (TLR) 13 and TLR2 are the major sensors of Gram‐positive bacteria in mice. TLR13 recognizes Sa19, a specific 23S ribosomal (r) RNA‐derived…”
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Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling by Rückert, Tamina, Andrieux, Geoffroy, Boerries, Melanie, Hanke-Müller, Kathrin, Woessner, Nadine M, Doetsch, Stephanie, Schell, Christoph, Aumann, Konrad, Kolter, Julia, Schmitt-Graeff, Annette, Schiff, Marcel, Braun, Lukas M, Haring, Eileen, Kissel, Sandra, Siranosian, Benjamin A, Bhatt, Ami S, Nordkild, Peter, Wehkamp, Jan, Jensen, Benjamin A H, Minguet, Susana, Duyster, Justus, Zeiser, Robert, Köhler, Natalie

“…Acute graft-versus-host disease (aGVHD), which is driven by allogeneic T cells, has a high mortality rate and limited treatment options. Human β-defensin 2…”
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Mycobacteria exploit nitric oxide‐induced transformation of macrophages into permissive giant cells by Gharun, Kourosh, Senges, Julia, Seidl, Maximilian, Lösslein, Anne, Kolter, Julia, Lohrmann, Florens, Fliegauf, Manfred, Elgizouli, Magdeldin, Vavra, Martina, Schachtrup, Kristina, Illert, Anna L, Gilleron, Martine, Kirschning, Carsten J, Triantafyllopoulou, Antigoni, Henneke, Philipp

“…Immunity to mycobacteria involves the formation of granulomas, characterized by a unique macrophage (MΦ) species, so‐called multinucleated giant cells (MGC)…”
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Streptococci Engage TLR13 on Myeloid Cells in a Site-Specific Fashion by Kolter, Julia, Feuerstein, Reinhild, Spoeri, Evelyne, Gharun, Kourosh, Elling, Roland, Trieu-Cuot, Patrick, Goldmann, Tobias, Waskow, Claudia, Chen, Zhijian J, Kirschning, Carsten J, Deshmukh, Sachin D, Henneke, Philipp

“…Streptococci are common human colonizers with a species-specific mucocutaneous distribution. At the same time, they are among the most important and most…”
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Erratum To: Mycobacteria exploit nitric oxide‐induced transformation of macrophages into permissive giant cells by Gharun, Kourosh, Senges, Julia, Seidl, Maximilian, Lösslein, Anne, Kolter, Julia, Lohrmann, Florens, Fliegauf, Manfred, Elgizouli, Magdeldin, Alber, Marco, Vavra, Martina, Schachtrup, Kristina, Illert, Anna L, Gilleron, Martine, Kirschning, Carsten J, Triantafyllopoulou, Antigoni, Henneke, Philipp

“…Graphical Abstract…”
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