Search Results - "Kolpak, D C"

Antidiarrheal activity of alpha-2 adrenoceptor agonist SK&F 35886 by Fondacaro, J D, McCafferty, G P, Kolpak, D C, Smith, P L

“…Alpha-2 adrenoceptor agonists exhibit antidiarrheal activity in animal models and in humans. However, hypotensive and sedative side effects seriously limit the…”
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Mediation of the hypotensive action of systemic clonidine in the rat by alpha 2-adrenoceptors by Hieble, J P, Kolpak, D C

“…1. During the past few years it has been shown that the sympatholytic effect resulting from localized microinjection of clonidine and other imidazolines into…”
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Mediation of the hypotensive action of systemic clonidine in the rat by α2‐adrenoceptors by Hieble, J. Paul, Kolpak, David C.

“…1 During the past few years it has been shown that the sympatholytic effect resulting from localized microinjection of clonidine and other imidazolines into…”
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Cecectomized rat. A model of experimental secretory diarrhea in conscious animals by Fondacaro, J D, Kolpak, D C, Burnham, D B, McCafferty, G P

“…Evaluation of antisecretory antidiarrheal agents in animal models is limited primarily to extrapolations of efficacy from enteropooling studies in vivo,…”
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Effects of alpha1-adrenoceptor antagonists on agonist and tilt-induced changes in blood pressure: relationships to uroselectivity by Hieble, J P, Kolpak, D C, McCafferty, G P, Ruffolo, Jr, R R, Testa, R, Leonardi, A

“…We evaluated the uroselectivity of a series of alpha1-adrenoceptor antagonists by comparing their potency against phenylephrine-induced increases in urethral…”
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Effects of α1-adrenoceptor antagonists on agonist and tilt-induced changes in blood pressure: relationships to uroselectivity by HIEBLE, J. P, KOLPAK, D. C, MCCAFFERTY, G. P, RUFFOLO, R. R, TESTA, R, LEONARDI, A

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