Search Results - "Kolobkov, Dmitry"

Effects of personalized diets by prediction of glycemic responses on glycemic control and metabolic health in newly diagnosed T2DM: a randomized dietary intervention pilot trial by Rein, Michal, Ben-Yacov, Orly, Godneva, Anastasia, Shilo, Smadar, Zmora, Niv, Kolobkov, Dmitry, Cohen-Dolev, Noa, Wolf, Bat-Chen, Kosower, Noa, Lotan-Pompan, Maya, Weinberger, Adina, Halpern, Zamir, Zelber-Sagi, Shira, Elinav, Eran, Segal, Eran

“…Dietary modifications are crucial for managing newly diagnosed type 2 diabetes mellitus (T2DM) and preventing its health complications, but many patients fail…”
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An overview of germline variations in genes of primary immunodeficiences through integrative analysis of ClinVar, HGMD® and dbSNP databases by Salnikova, Lyubov E., Kolobkov, Dmitry S., Sviridova, Darya A., Abilev, Serikbai K.

“…Primary immunodeficiencies (PID) are a diverse group of genetic disorders caused by inadequate development and function of immune system. Identifying genetic…”
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COVID-19 severity: does the genetic landscape of rare variants matter? by Khadzhieva, Maryam B, Gracheva, Alesya S, Belopolskaya, Olesya B, Kolobkov, Dmitry S, Kashatnikova, Darya A, Redkin, Ivan V, Kuzovlev, Artem N, Grechko, Andrey V, Salnikova, Lyubov E

“…Rare variants affecting host defense against pathogens may be involved in COVID-19 severity, but most rare variants are not expected to have a major impact on…”
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Pneumonia and Related Conditions in Critically Ill Patients—Insights from Basic and Experimental Studies by Kashatnikova, Darya A., Khadzhieva, Maryam B., Kolobkov, Dmitry S., Belopolskaya, Olesya B., Smelaya, Tamara V., Gracheva, Alesya S., Kalinina, Ekaterina V., Larin, Sergey S., Kuzovlev, Artem N., Salnikova, Lyubov E.

“…Pneumonia is an acute infectious disease with high morbidity and mortality rates. Pneumonia’s development, severity and outcome depend on age, comorbidities…”
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Cytokines mapping for tissue-specific expression, eQTLs and GWAS traits by Salnikova, Lyubov E., Khadzhieva, Maryam B., Kolobkov, Dmitry S., Gracheva, Alesya S., Kuzovlev, Artem N., Abilev, Serikbay K.

“…Dysregulation in cytokine production has been linked to the pathogenesis of various immune-mediated traits, in which genetic variability contributes to the…”
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Biological findings from the PheWAS catalog: focus on connective tissue-related disorders (pelvic floor dysfunction, abdominal hernia, varicose veins and hemorrhoids) by Salnikova, Lyubov E., Khadzhieva, Maryam B., Kolobkov, Dmitry S.

“…Pelvic floor dysfunction, specifically genital prolapse (GP) and stress urinary inconsistency (SUI) presumably co-occur with other connective tissue disorders…”
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Expression changes in pelvic organ prolapse: a systematic review and in silico study by Khadzhieva, Maryam B., Kolobkov, Dmitry S., Kamoeva, Svetlana V., Salnikova, Lyubov E.

“…Pelvic organ prolapse (POP) is a highly disabling condition common for a vast number of women worldwide. To contribute to existing knowledge in POP…”
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10 K: a large‐scale prospective longitudinal study in Israel by Shilo, Smadar, Bar, Noam, Keshet, Ayya, Talmor-Barkan, Yeela, Rossman, Hagai, Godneva, Anastasia, Aviv, Yaron, Edlitz, Yochai, Reicher, Lee, Kolobkov, Dmitry, Wolf, Bat Chen, Lotan-Pompan, Maya, Levi, Kohava, Cohen, Ori, Saranga, Hila, Weinberger, Adina, Segal, Eran

“…The 10 K is a large-scale prospective longitudinal cohort and biobank that was established in Israel. The primary aims of the study include development of…”
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GRAPE: genomic relatedness detection pipeline [version 2; peer review: 2 approved] by Medvedev, Alexander, Lebedev, Mikhail, Ponomarev, Andrew, Kosaretskiy, Mikhail, Osipenko, Dmitriy, Tischenko, Alexander, Kosaretskiy, Egor, Wang, Hui, Kolobkov, Dmitry, Chamberlain-Evans, Vitalina, Vakhitov, Ruslan, Nikonorov, Pavel

“…Classifying the degree of relatedness between pairs of individuals has both scientific and commercial applications. As an example, genome-wide association…”
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Rare Variants in Primary Immunodeficiency Genes and Their Functional Partners in Severe COVID-19 by Khadzhieva, Maryam B, Kolobkov, Dmitry S, Kashatnikova, Darya A, Gracheva, Alesya S, Redkin, Ivan V, Kuzovlev, Artem N, Salnikova, Lyubov E

“…The development of severe COVID-19, which is a complex multisystem disease, is thought to be associated with many genes whose action is modulated by numerous…”
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Genes and Diseases: Insights from Transcriptomics Studies by Kolobkov, Dmitry S., Sviridova, Darya A., Abilev, Serikbai K., Kuzovlev, Artem N., Salnikova, Lyubov E.

“…Results of expression studies can be useful to clarify the genotype-phenotype relationship. However, according to data from recent literature, there is a large…”
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BREAst Cancer Personalised NuTrition (BREACPNT): dietary intervention in breast cancer survivors treated with endocrine therapy – a protocol for a randomised clinical trial by Rein, Michal Sela, Dadiani, Maya, Godneva, Anastasia, Bakalenik-Gavry, Michal, Morzaev-Sulzbach, Dana, Vachnish, Yaeli, Kolobkov, Dmitry, Lotan-Pompan, maya, Weinberger, Adina, Segal, Eran, Gal-Yam, Einav Nili

“…IntroductionBreast cancer survivors treated with adjuvant endocrine therapy commonly experience weight gain, which has been associated with low adherence to…”
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Efficacy of federated learning on genomic data: a study on the UK Biobank and the 1000 Genomes Project by Kolobkov, Dmitry, Mishra Sharma, Satyarth, Medvedev, Aleksandr, Lebedev, Mikhail, Kosaretskiy, Egor, Vakhitov, Ruslan

“…Combining training data from multiple sources increases sample size and reduces confounding, leading to more accurate and less biased machine learning models…”
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Rationale and design of a randomised controlled trial testing the effect of personalised diet in individuals with pre-diabetes or type 2 diabetes mellitus treated with metformin by Htet, Thaw D, Godneva, Anastasia, Liu, Zhixin, Chalmers, Eliza, Kolobkov, Dmitry, Snaith, Jennifer R, Richens, Renee, Toth, Krisztina, Danta, Mark, Hng, Tien-Ming, Elinav, Eran, Segal, Eran, Greenfield, Jerry R, Samocha-Bonet, Dorit

“…IntroductionMetformin and diets aimed at promoting healthy body weight are the first line in treating type 2 diabetes mellitus (T2DM). Clinical practice,…”
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A Prediction Model to Prioritize Individuals for a SARS-CoV-2 Test Built from National Symptom Surveys by Shoer, Saar, Karady, Tal, Keshet, Ayya, Shilo, Smadar, Rossman, Hagai, Gavrieli, Amir, Meir, Tomer, Lavon, Amit, Kolobkov, Dmitry, Kalka, Iris, Godneva, Anastasia, Cohen, Ori, Kariv, Adam, Hoch, Ori, Zer-Aviv, Mushon, Castel, Noam, Sudre, Carole, Zohar, Anat Ekka, Irony, Angela, Spector, Tim, Geiger, Benjamin, Hizi, Dorit, Shalev, Varda, Balicer, Ran, Segal, Eran

“…The gold standard for COVID-19 diagnosis is detection of viral RNA through PCR. Due to global limitations in testing capacity, effective prioritization of…”
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Verification of the Chromosome Region 9q21 Association with Pelvic Organ Prolapse Using RegulomeDB Annotations by Abilev, Serikbay K., Ivanova, Anastasia V., Kamoeva, Svetlana V., Kolobkov, Dmitry S., Khadzhieva, Maryam B., Salnikova, Lyubov E.

“…Pelvic organ prolapse (POP) is a common highly disabling disorder with a large hereditary component. It is characterized by a loss of pelvic floor support that…”
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Personalized Postprandial Glucose Response-Targeting Diet Versus Mediterranean Diet for Glycemic Control in Prediabetes by Ben-Yacov, Orly, Godneva, Anastasia, Rein, Michal, Shilo, Smadar, Kolobkov, Dmitry, Koren, Netta, Cohen Dolev, Noa, Travinsky Shmul, Tamara, Wolf, Bat Chen, Kosower, Noa, Sagiv, Keren, Lotan-Pompan, Maya, Zmora, Niv, Weinberger, Adina, Elinav, Eran, Segal, Eran

“…To compare the clinical effects of a personalized postprandial-targeting (PPT) diet versus a Mediterranean (MED) diet on glycemic control and metabolic health…”
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An overview of germline variations in genes of primary immunodeficiences through integrative analysis of ClinVar, HGMD.sup.® and dbSNP databases by Salnikova, Lyubov E, Kolobkov, Dmitry S, Sviridova, Darya A, Abilev, Serikbai K

“…Primary immunodeficiencies (PID) are a diverse group of genetic disorders caused by inadequate development and function of immune system. Identifying genetic…”
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The Gut Microbiome of Adults With Type 1 Diabetes and Its Association With the Host Glycemic Control by Shilo, Smadar, Godneva, Anastasia, Rachmiel, Marianna, Korem, Tal, Bussi, Yuval, Kolobkov, Dmitry, Karady, Tal, Bar, Noam, Wolf, Bat Chen, Glantz-Gashai, Yitav, Cohen, Michal, Zuckerman-Levin, Nehama, Shehadeh, Naim, Gruber, Noah, Levran, Neriya, Koren, Shlomit, Weinberger, Adina, Pinhas-Hamiel, Orit, Segal, Eran

“…Previous studies have demonstrated an association between gut microbiota composition and type 1 diabetes (T1D) pathogenesis. However, little is known about the…”
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Prediction of Personal Glycemic Responses to Food for Individuals With Type 1 Diabetes Through Integration of Clinical and Microbial Data by Shilo, Smadar, Godneva, Anastasia, Rachmiel, Marianna, Korem, Tal, Kolobkov, Dmitry, Karady, Tal, Bar, Noam, Wolf, Bat Chen, Glantz-Gashai, Yitav, Cohen, Michal, Zuckerman Levin, Nehama, Shehadeh, Naim, Gruber, Noah, Levran, Neriya, Koren, Shlomit, Weinberger, Adina, Pinhas-Hamiel, Orit, Segal, Eran

“…Despite technological advances, results from various clinical trials have repeatedly shown that many individuals with type 1 diabetes (T1D) do not achieve…”
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