Search Results - "Kolnagou, A."

The design and development of deferiprone (L1) and other iron chelators for clinical use: targeting methods and application prospects by Kontoghiorghes, G J, Pattichis, K, Neocleous, K, Kolnagou, A

“…Iron is essential for all human cells as well as neoplastic cells and invading microbes. Natural and synthetic iron chelators could affect biological processes…”
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Safety issues of iron chelation therapy in patients with normal range iron stores including thalassaemia, neurodegenerative, renal and infectious diseases by Kontoghiorghes, G J, Kolnagou, A, Peng, C-T, Shah, S V, Aessopos, A

“…An increased number of thalassaemia patients treated with effective chelation therapy protocols are achieving body iron levels similar to those of normal…”
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Deferiprone versus desferrioxamine in thalassaemia, and T2 validation and utility by Kontoghiorghes, GJ, Kolnagou, A

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Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone by Telfer, Paul T, Warburton, Fiona, Christou, Soteroula, Hadjigavriel, Michael, Sitarou, Maria, Kolnagou, Anita, Angastiniotis, Michael

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PF785 CHANGING CAUSES OF MORTALITY IN TDT DURING THE ERA OF ORAL CHELATION THERAPY FROM 2000 TO 2018 by Telfer, P., Kountouris, P., Christou, S., Hadjigavriel, M., Sitarou, M., Kolnagou, A., Kleanthous, M.

“…Background: Heart disease due to transfusion iron overload has been previously reported as the predominant cause of death in transfusion dependent thalassaemia…”
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Dietary and pharmacological factors affecting iron absorption in mice and man (Comment for a Letter to the editor) by Kontoghiorghe, Christina N, Kolnagou, Annita, Kontoghiorghes, George J

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Low Serum Ferritin Levels are Misleading for Detecting Cardiac Iron Overload and Increase the Risk of Cardiomyopathy in Thalassemia Patients. The Importance of Cardiac Iron Overload Monitoring Using Magnetic Resonance Imaging T2 and T2 by Kolnagou, Annita, Economides, Charalambos, Eracleous, Eleni, Kontoghiorghes, George J.

“…The incidence of cardiomyopathy was monitored in a 6-year follow-up study involving 56 transfused thalassemia patients treated with deferoxamine (DFO),…”
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Molecular factors and mechanisms affecting iron and other metal excretion or absorption in health and disease: the role of natural and synthetic chelators by Kontoghiorghes, George J, Kolnagou, Annita

“…The maintenance of iron and other essential metal ion balance in humans is based on the presence of homeostatic mechanisms of regulatory absorption, storage,…”
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New approach to iron chelation therapy using effective deferiprone therapy or combination with deferoxamine by Kolnagou, A, Kontoghiorghes, G J

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Prophylactic use of deferiprone (L1) and magnetic resonance imaging T2 or T2 for preventing heart disease in thalassaemia by Kolnagou, Annita, Fessas, Charis, Papatryphonas, Antonis, Economides, Charalambos, Kontoghiorghes, George J.

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Transfusional iron overload and chelation therapy with deferoxamine and deferiprone (L1) by Kontoghiorghes, George J, Pattichi, Katerina, Hadjigavriel, Michael, Kolnagou, Annita

“…Iron is essential for all living organisms. Under normal conditions there is no regulatory and rapid iron excretion in humans and body iron levels are mainly…”
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Development of the new oral chelators ICL670, L1 NAll and GT56-252 and comparison with the iron chelating drugs deferiprone and deferoxamine by Kontoghiorghes, G J, Pattichis, K, Neocleous, K, Kolnagou, A

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Iron mobilisation from transferrin by deferiprone (L1) by Kontoghiorghes, George J, Kolnagou, Annita, Eracleous, Eleni, Evans, Robert W.

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Deferiprone versus desferrioxamine in thalassaemia, and T2 validation and utility by Pierre, TG St

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Introduction of deferiprone in thalassaemia patients with cardiac iron overload not responding to deferoxamine by Yazman, D, Kolnagou, A, Economides, C, Moutiris, J A, Kontoghiorghes, G J

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How relevant are serum ferritin levels and MRIT2 for assessing cardiac iron load in thalassaemia by Kolnagou, A, Yazman, D, Economides, C, Eracleous, E, Kontoghiorghes, G J

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Comparison of MRIT2 and MRIT2 in the diagnosis of cardiac iron load in thalassaemia patients by Economides, C, Eracleous, E, Yazman, D, Kolnagou, A, Kontoghiorghes, G J

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Deferiprone for thalassaemia by Kontoghiorghes, GJ, Agarwal, MB, Grady, RW, Kolnagou, A, Marx, JJ

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Effects on Mycobacterium avium replication in normal human macrophages by deferiprone (L1) and other Iron chelators possible implications on toxicity by DOUVAS, George S, MAY, Mary H, KOLNAGOU, Annita, KONTOGHIORGHES, George J

“…Mycobacterium avium growth in cultured human macrophages is influenced by serum lipids, transferrin and iron levels. Iron-saturated transferrin enhances M…”
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