Search Results - "Kolliopoulos, Constantinos"

Regulation of hyaluronan biosynthesis and clinical impact of excessive hyaluronan production by Heldin, Paraskevi, Lin, Chun-Yu, Kolliopoulos, Constantinos, Chen, Yen-Hsu, Skandalis, Spyros S.

“…The tightly regulated biosynthesis and catabolism of the glycosaminoglycan hyaluronan, as well as its role in organizing tissues and cell signaling, is crucial…”
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Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study by van der Heijden, Jaap, Kolliopoulos, Constantinos, Skorup, Paul, Sallisalmi, Marko, Heldin, Paraskevi, Hultström, Michael, Tenhunen, Jyrki

“…Background Plasma hyaluronan concentrations are increased during sepsis but underlying mechanisms leading to high plasma hyaluronan concentration are poorly…”
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Involvement of hyaluronan and CD44 in cancer and viral infections by Heldin, Paraskevi, Kolliopoulos, Constantinos, Lin, Chun-Yu, Heldin, Carl-Henrik

“…•Hyaluronan is overexpressed in inflammation, infection and cancer and the hyaluronan levels correlate to disease severity.•The hyaluronan receptor CD44…”
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Metabolic Signaling in Cancer Metastasis by Krieg, Sarah, Fernandes, Sara Isabel, Kolliopoulos, Constantinos, Liu, Ming, Fendt, Sarah-Maria

“…Metastases, which are the leading cause of death in patients with cancer, have metabolic vulnerabilities. Alterations in metabolism fuel the energy and…”
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Has2 natural antisense RNA and Hmga2 promote Has2 expression during TGFβ-induced EMT in breast cancer by Kolliopoulos, Constantinos, Lin, Chun-Yu, Heldin, Carl-Henrik, Moustakas, Aristidis, Heldin, Paraskevi

“…The glycosaminoglycan hyaluronan has a crucial role in tissue organization and cell signaling. Hyaluronan accumulates in conjunction with rapid tissue…”
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CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence by Kolliopoulos, Constantinos, Ali, Mohamad Moustafa, Castillejo-Lopez, Casimiro, Heldin, Carl-Henrik, Heldin, Paraskevi

“…Glioblastoma multiforme (GBM) is a lethal brain tumor, characterized by enhanced proliferation and invasion, as well as increased vascularization and…”
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TRAF4/6 Is Needed for CD44 Cleavage and Migration via RAC1 Activation by Kolliopoulos, Constantinos, Chatzopoulos, Athanasios, Skandalis, Spyros S, Heldin, Carl-Henrik, Heldin, Paraskevi

“…The hyaluronan receptor CD44 can undergo proteolytic cleavage in two steps, leading to the release of its intracellular domain; this domain is translocated to…”
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Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output by Kolliopoulos, Constantinos, Raja, Erna, Razmara, Masoud, Heldin, Paraskevi, Heldin, Carl-Henrik, Moustakas, Aristidis, van der Heide, Lars P.

“…TGFβ signaling via SMAD proteins and protein kinase pathways up- or down-regulates the expression of many genes and thus affects physiological processes, such…”
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High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity by Lin, Chun-Yu, Kolliopoulos, Constantinos, Huang, Chung-Hao, Tenhunen, Jyrki, Heldin, Carl-Henrik, Chen, Yen-Hsu, Heldin, Paraskevi

“…A main pathological feature of severe dengue virus infection is endothelial hyper-permeability. The dengue virus nonstructural protein 1 (NS1) has been…”
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High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrityResearch in context by Chun-Yu Lin, Constantinos Kolliopoulos, Chung-Hao Huang, Jyrki Tenhunen, Carl-Henrik Heldin, Yen-Hsu Chen, Paraskevi Heldin

“…Background: A main pathological feature of severe dengue virus infection is endothelial hyper-permeability. The dengue virus nonstructural protein 1 (NS1) has…”
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