Search Results - "Kollia, G. D."

Lack of a pharmacokinetic drug-drug interaction between lithium and valproate when co-administered with aripiprazole by Boulton, D. W., Kollia, G. D., Mallikaarjun, S., Kornhauser, D. M.

“…Summary What is known and Objective:  The antipsychotic, aripiprazole, plus lithium or valproate demonstrates rapid and significant improvement in manic…”
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Benefits and Disadvantages of Joint Hypermobility among Musicians by Larsson, Lars-Goran, Baum, John, Mudholkar, Govind S, Kollia, Georgia D

“…Joint hypermobility, also known as joint laxity and defined as a range of motion in excess of normal, 1 is common enough to evoke curiosity, but until recently…”
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A Dose-Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Gatifloxacin in Healthy Adult Men by Gajjar, Diptee A., LaCreta, Frank P., Uderman, Howard D., Kollia, Georgia D., Duncan, Glenn, Birkhofer, Martin J., Grasela, Dennis M.

“…Study Objectives. To examine single‐ and multiple‐dose safety, tolerability and pharmacokinetics of gatifloxacin administered as daily 1‐hour intravenous…”
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Effect of Multiple-Dose Gatifloxacin or Ciprofloxacin on Glucose Homeostasis and Insulin Production in Patients with Noninsulin-Dependent Diabetes Mellitus Maintained with Diet and Exercise by Gajjar, Diptee A., LaCreta, Frank P., Kollia, Georgia D., Stolz, Randall R., Berger, Sheldon, Smith, William B., Swingle, Mary, Grasela, Dennis M.

“…Study Objectives. To compare the effects of gatifloxacin and ciprofloxacin on glucose homeostasis, including glucose tolerance test (GTT), pancreatic β‐cell…”
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Open-Label, Nonrandomized Study of the Effects of Gatifloxacin on the Pharmacokinetics of Midazolam in Healthy Male Volunteers by Grasela, Dennis M., LaCreta, Frank P., Kollia, Georgia D., Randall, Diane M., Uderman, Howard D.

“…Study Objective. To confirm findings from an in vitro study that showed gatifloxacin did not substantially inhibit cytochrome P450 (CYP) 3A4 model substrate…”
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Interchangeability of 400-mg Intravenous and Oral Gatifloxacin in Healthy Adults by LaCreta, Frank P., Kaul, Sanjeev, Kollia, Georgia D., Duncan, Glenn, Randall, Dianne M., Grasela, Dennis M.

“…Study Objective. To evaluate the interchangeability of 400‐mg intravenous and oral doses of gatifloxacin. Design. Randomized, open‐label, crossover study…”
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Age and Gender Effects on the Pharmacokinetics of Gatifloxacin by LaCreta, Frank P., Kollia, Georgia D., Duncan, Glenn, Behr, Douglas, Grasela, Dennis M.

“…Study Objective. To compare the pharmacokinetics and safety of gatifloxacin in elderly (≥ 65 yrs) and young (18–45 yrs) men and women. Design. Open‐label,…”
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Evaluation of the effect of food on the pharmacokinetics of avitriptan by Marathe, P. H., Greene, D. S., Kollia, G. D., Barbhaiya, R. H.

“…Bioavailability of avitriptan was found to decrease significantly when administered 5 min after a standard high fat meal. The studies described herein were…”
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Safety and Pharmacokinetics of a Single Oral Dose of Gatifloxacin in Patients with Moderate to Severe Hepatic Impairment by Grasela, Dennis M., Christofalo, Barbara, Kollia, Georgia D., Duncan, Glenn, Noveck, Robert, Manning Jr, James A., LaCreta, Frank P.

“…Study Objectives. To assess the safety and pharmacokinetics of oral gatifloxacin 400 mg in subjects with and without hepatic impairment, and the need to modify…”
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A pharmacokinetic interaction study of avitriptan and propranolol by Marathe, Punit H., Greene, Douglas S., Kollia, Georgia D., Barbhaiya, Rashmi H.

“…Objective To assess whether a clinically significant change in the pharmacokinetics of avitriptan and propranolol is observed in healthy subjects after…”
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The Effects of Age and Gender on the Single Dose Pharmacokinetics of Avitriptan Administered to Healthy Volunteers by Marathe, Punit H., Greene, Douglas S., Kollia, Georgia D., Barbhaiya, Rashmi H.

“…The effects of age and gender on the single dose pharmacokinetics of avitriptan and its three metabolites were assessed in 15 young men, 15 young women, 15…”
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A Graphical Procedure for Comparing Goodness-of-Fit Tests by Mudholkar, Govind S., Kollia, Georgia D., Lin, C. Thomas, Patel, Kartik R.

“…A method for comparing tests of normality using their `isotones', i.e. contours on the surfaces representing P-values, is proposed. Select a family of…”
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The Pharmacokinetics and Pharmacodynamics of Irbesartan in Heart Failure by Kostis, J.B., Vachharajani, N.N., Hadjilambris, O.W., Kollia, G.D., Palmisano, M., Marino, M.R.

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Pharmacodynamics and Pharmacokinetics of Omapatrilat in Heart Failure by Kostis, John B., Klapholz, Marc, Delaney, Ms. Carol, Vesterqvist, Ole, Cohen, Marvin, Manning Jr, James A., Jemal, Mohammed, Kollia, Georgia D., Liao, Wei-Chi

“…The purpose of this study was to determine the pharmacodynamics and pharmacokinetics of omapatrilat, administered orally (25 mg) or intravenously (10 mg) in 19…”
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Lack of a pharmacokinetic drug-drug interaction between lithium and valproate when co-administered with aripiprazole: Pharmacokinetics of lithium/valproate with aripiprazole by Boulton, D. W., Kollia, G. D., Mallikaarjun, S., Kornhauser, D. M.

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A Generalization of the Weibull Distribution with Application to the Analysis of Survival Data by Mudholkar, Govind S., Srivastava, Deo Kumar, Kollia, Georgia D.

“…The Weibull distribution, which is frequently used for modeling survival data, is embedded in a larger family obtained by introducing an additional shape…”
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Interchangeability of 400-mg intravenous and oral gatifloxacin in healthy adults: Pharmacokinetics of gatifloxacin: dosing considerations and use in special populations by LACRETA, F. P, KAUL, S, KOLLIA, G. D, DUNCAN, G, RANDALL, D. M, GRASELA, D. M

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Age and gender effects on the pharmacokinetics of gatifloxacin: Pharmacokinetics of gatifloxacin: dosing considerations and use in special populations by LACRETA, F. P, KOLLIA, G. D, DUNCAN, G, BEHR, D, GRASELA, D. M

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A dose-escalation study of the safety, tolerability, and pharmacokinetics of intravenous gatifloxacin in healthy adult men: Pharmacokinetics of gatifloxacin: dosing considerations and use in special populations by GAJJAR, D. A, LACRETA, F. P, UDERMAN, H. D, KOLLIA, G. D, DUNCAN, G, BIRKHOFER, M. J, GRASELA, D. M

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Safety and pharmacokinetics of a single oral dose of gatifloxacin in patients with moderate to severe hepatic impairment: Pharmacokinetics of gatifloxacin: dosing considerations and use in special populations by GRASELA, D. M, CHRISTOFALO, B, KOLLIA, G. D, DUNCAN, G, NOVECK, R, MANNING, J. A, LACRETA, F. P

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