Search Results - "Kollet, O"

The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice by Lapidot, T, Kollet, O

“…Hematopoietic stem cells are identified based on their functional ability to migrate via the blood circulation of transplanted recipients, to home to the host…”
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Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells by Dar, A, Schajnovitz, A, Lapid, K, Kalinkovich, A, Itkin, T, Ludin, A, Kao, W-M, Battista, M, Tesio, M, Kollet, O, Cohen, N N, Margalit, R, Buss, E C, Baleux, F, Oishi, S, Fujii, N, Larochelle, A, Dunbar, C E, Broxmeyer, H E, Frenette, P S, Lapidot, T

“…Steady-state egress of hematopoietic progenitor cells can be rapidly amplified by mobilizing agents such as AMD3100, the mechanism, however, is poorly…”
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MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling by Itkin, T, Kumari, A, Schneider, E, Gur-Cohen, S, Ludwig, C, Brooks, R, Kollet, O, Golan, K, Khatib-Massalha, E, Russo, C M, Chisholm, J D, Rouhi, A, Geiger, H, Hornstein, E, Kerr, W G, Kuchenbauer, F, Lapidot, T

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Physiologic corticosterone oscillations regulate murine hematopoietic stem/progenitor cell proliferation and CXCL12 expression by bone marrow stromal progenitors by Kollet, O, Vagima, Y, D'Uva, G, Golan, K, Canaani, J, Itkin, T, Gur-Cohen, S, Kalinkovich, A, Caglio, G, Medaglia, C, Ludin, A, Lapid, K, Shezen, E, Neufeld-Cohen, A, Varol, D, Chen, A, Lapidot, T

“…The role of corticosterone (Cort), the immune system’s major stress hormone, in the regulation of hematopoietic stem and progenitor cells (HSPCs) and their…”
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The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2mnull mice by Lapidot, T, Kollet, O

“…Hematopoietic stem cells are identified based on their functional ability to migrate via the blood circulation of transplanted recipients, to home to the host…”
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How do stem cells find their way home? by Lapidot, Tsvee, Dar, Ayelet, Kollet, Orit

“…Migration of hematopoietic stem cells through the blood, across the endothelial vasculature to different organs and to their bone marrow (BM) niches, requires…”
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Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice by LAPIDOT, T, GRUNBERGER, T, VORMOOR, J, ESTROV, Z, KOLLET, O, BUNIN, N, ZAIZOV, R, WILLIAMS, D. E, FREEDMAN, M. H

“…Most juvenile chronic myelogenous leukemia (JCML) cells have limited long-term proliferative capacity, and only a minority of immature cells give rise to…”
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CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+stem/progenitor cells to bone marrow by Avigdor, Abraham, Goichberg, Polina, Shivtiel, Shoham, Dar, Ayelet, Peled, Amnon, Samira, Sarit, Kollet, Orit, Hershkoviz, Rami, Alon, Ronen, Hardan, Izhar, Ben-Hur, Herzl, Naor, David, Nagler, Arnon, Lapidot, Tsvee

“…Trafficking of human CD34+stem/progenitor cells (HSCs/HPCs) is regulated by chemokines, cytokines, proteolytic enzymes, and adhesion molecules. We report that…”
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Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells by Lapidot, Tsvee, Dar, Ayelet, Goichberg, Polina, Shinder, Vera, Kalinkovich, Alexander, Kollet, Orit, Netzer, Neta, Margalit, Raanan, Zsak, Marion, Nagler, Arnon, Hardan, Izhar, Resnick, Igor, Rot, Antal

“…Regulation of the availability of chemokine SDF-1 (CXCL12) in bone marrow is still not fully understood. Here we describe a unique function for the chemokine…”
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HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver by Kollet, Orit, Shivtiel, Shoham, Chen, Yuan-Qing, Suriawinata, Jenny, Thung, Swan N., Dabeva, Mariana D., Kahn, Joy, Spiegel, Asaf, Dar, Ayelet, Samira, Sarit, Goichberg, Polina, Kalinkovich, Alexander, Arenzana-Seisdedos, Fernando, Nagler, Arnon, Hardan, Izhar, Revel, Michel, Shafritz, David A., Lapidot, Tsvee

“…Hematopoietic stem cells rarely contribute to hepatic regeneration, however, the mechanisms governing their homing to the liver, which is a crucial first step,…”
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Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice by Kollet, O, Spiegel, A, Peled, A, Petit, I, Byk, T, Hershkoviz, R, Guetta, E, Barkai, G, Nagler, A, Lapidot, T

“…Stem cell homing into the bone microenvironment is the first step in the initiation of marrow-derived blood cells. It is reported that human severe combined…”
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The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34+ cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice by Peled, Amnon, Kollet, Orit, Ponomaryov, Tanya, Petit, Isabelle, Franitza, Suzanna, Grabovsky, Valentin, Slav, Michal Magid, Nagler, Arnon, Lider, Ofer, Alon, Ronen, Zipori, Dov, Lapidot, Tsvee

“…Hematopoietic stem cell homing and engraftment require several adhesion interactions, which are not fully understood. Engraftment of nonobese/severe combined…”
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Dependence of Human Stem Cell Engraftment and Repopulation of NOD/SCID Mice on CXCR4 by Peled, Amnon, Petit, Isabelle, Kollet, Orit, Magid, Michal, Ponomaryov, Tanya, Byk, Tamara, Nagler, Arnon, Ben-Hur, Herzl, Many, Ariel, Shultz, Leonard, Lider, Ofer, Alon, Ronen, Zipori, Dov, Lapidot, Tsvee

“…Stem cell homing and repopulation are not well understood. The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4 were found to be critical…”
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Unique SDF-1–induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling by Spiegel, Asaf, Kollet, Orit, Peled, Amnon, Abel, Loya, Nagler, Arnon, Bielorai, Bella, Rechavi, Gideon, Vormoor, Josef, Lapidot, Tsvee

“…The mechanisms governing migration and extramedullary dissemination of leukemic cells remain obscure. In this study the migration and in vivo homing to the…”
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Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally by Varfolomeev, Eugene E, Schuchmann, Marcus, Luria, Victor, Chiannilkulchai, Nuchanard, Beckmann, Jacques S, Mett, Igor L, Rebrikov, Denis, Brodianski, Vadim M, Kemper, Oliver C, Kollet, Orit, Lapidot, Tsvee, Soffer, Dror, Sobe, Tama, Avraham, Karen B, Goncharov, Tanya, Holtmann, Helmut, Lonai, Peter, Wallach, David

“…Homozygous targeted disruption of the mouse Caspase 8 ( Casp8) gene was found to be lethal in utero. The Caspase 8 null embryos exhibited impaired heart muscle…”
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Human CD34+CXCR4− sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation by Kollet, Orit, Petit, Isabelle, Kahn, Joy, Samira, Sarit, Dar, Ayelet, Peled, Amnon, Deutsch, Varda, Gunetti, Monica, Piacibello, Wanda, Nagler, Arnon, Lapidot, Tsvee

“…Homing and repopulation of nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice by enriched human CD34+stem cells from cord blood, bone marrow, or…”
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Engraftment in Nonobese Diabetic Severe Combined Immunodeficient Mice of Human CD34+ Cord Blood Cells After Ex Vivo Expansion: Evidence for the Amplification and Self-Renewal of Repopulating Stem Cells by Piacibello, Wanda, Sanavio, Fiorella, Severino, Antonella, Danè, Alessandra, Gammaitoni, Loretta, Fagioli, Franca, Perissinotto, Eliana, Cavalloni, Giuliana, Kollet, Orit, Lapidot, Tsvee, Aglietta, Massimo

“…Understanding the repopulating characteristics of human hematopoietic stem/progenitor cells is crucial for predicting their performance after transplant into…”
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Engraftment in Nonobese Diabetic Severe Combined Immunodeficient Mice of Human CD34+ Cord Blood Cells After Ex Vivo Expansion: Evidence for the Amplification and Self-Renewal of Repopulating Stem Cells by Piacibello, Wanda, Sanavio, Fiorella, Severino, Antonella, Danè, Alessandra, Gammaitoni, Loretta, Fagioli, Franca, Perissinotto, Eliana, Cavalloni, Giuliana, Kollet, Orit, Lapidot, Tsvee, Aglietta, Massimo

“…Understanding the repopulating characteristics of human hematopoietic stem/progenitor cells is crucial for predicting their performance after transplant into…”
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The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/[B2m.sup.null] mice by Lapidot, T, Kollet, O

“…Hematopoietic stem cells are identified based on their functional ability to migrate via the blood circulation of transplanted recipients, to home to the host…”
Get full text

The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m super(null) mice by Lapidot, T, Kollet, O

“…Hematopoietic stem cells are identified based on their functional ability to migrate via the blood circulation of transplanted recipients, to home to the host…”
Get full text