Search Results - "Kolkman, Ruben W"

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  1. 1
    Density Control over MBD2 Receptor-Coated Surfaces Provides Superselective Binding of Hypermethylated DNA

    Density Control over MBD2 Receptor-Coated Surfaces Provides Superselective Binding of Hypermethylated DNA by Kolkman, Ruben W., Michel-Souzy, Sandra, Wasserberg, Dorothee, Segerink, Loes I., Huskens, Jurriaan

    Published in ACS applied materials & interfaces (14-09-2022)
    “…Using the biomarker hypermethylated DNA (hmDNA) for cancer detection requires a pretreatment to isolate or concentrate hmDNA from nonmethylated DNA. Affinity…”
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  2. 2
    Increasing the Sensitivity of Electrochemical DNA Detection by a Micropillar-Structured Biosensing Surface

    Increasing the Sensitivity of Electrochemical DNA Detection by a Micropillar-Structured Biosensing Surface by Movilli, Jacopo, Kolkman, Ruben W, Rozzi, Andrea, Corradini, Roberto, Segerink, Loes I, Huskens, Jurriaan

    Published in Langmuir (28-04-2020)
    “…The available active surface area and the density of probes immobilized on this surface are responsible for achieving high specificity and sensitivity in…”
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  3. 3
    Selective Enrichment of Hypermethylated DNA by a Multivalent Binding Platform

    Selective Enrichment of Hypermethylated DNA by a Multivalent Binding Platform by Kolkman, Ruben W., Segerink, Loes I., Huskens, Jurriaan

    Published in Advanced materials interfaces (01-12-2022)
    “…The preselection of hypermethylated DNA (hmDNA) from liquid biopsy samples is key to enable early‐stage cancer diagnostics. Due to limited selectivity of the…”
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