Search Results - "Kolk, L."

Triple-negative breast cancer: BRCAness and concordance of clinical features with BRCA1-mutation carriers by Lips, E H, Mulder, L, Oonk, A, van der Kolk, L E, Hogervorst, F B L, Imholz, A L T, Wesseling, J, Rodenhuis, S, Nederlof, P M

“…Background: BRCAness is defined as shared tumour characteristics between sporadic and BRCA-mutated cancers. However, how to exactly measure BRCAness and its…”
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Effects of a pre-visit online information tool about genetic counselling for ovarian cancer patients, a randomized controlled trial by Frijstein, M.M., Hamers, S.L., van Driel, W.J., Bleiker, E.M.A., van der Kolk, L., Sijstermans, R., Lok, C.A.R.

“…In the Netherlands, patients with ovarian cancer are offered genetic testing. Pre-test preparation may help counseling patients. The aim of this study was to…”
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Outcomes after prophylactic gastrectomy for hereditary diffuse gastric cancer by van der Kaaij, R. T., van Kessel, J. P., van Dieren, J. M., Snaebjornsson, P., Balagué, O., van Coevorden, F., van der Kolk, L. E., Sikorska, K., Cats, A., van Sandick, J. W.

“…Background Patients with hereditary diffuse gastric cancer and a CDH1 mutation have a 60–80 per cent lifetime risk of developing diffuse gastric cancer. Total…”
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Complement activation plays a key role in the side‐effects of rituximab treatment by Van Der Kolk, L. E., Grillo‐López, A. J., Baars, J. W., Hack, C. E., Van Oers, M. H. J.

“…Treatment with rituximab, a chimaeric anti‐CD20 monoclonal antibody, can be associated with moderate to severe first‐dose side‐effects, notably in patients…”
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Remarkable effects of imatinib in a family with young onset gastrointestinal stromal tumors and cutaneous hyperpigmentation associated with a germline KIT-Trp557Arg mutation: case report and literature overview by Farag, S., van der Kolk, L. E., van Boven, H. H., van Akkooi, A. C. J., Beets, G. L., Wilmink, J. W., Steeghs, N.

“…Gastrointestinal stromal tumors (GISTs) occur mostly sporadically. GISTs associated with a familial syndrome are very rare and are mostly wild type for KIT and…”
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Genetic counseling of patients with ovarian carcinoma: acceptance, timing, and psychological wellbeing by Van de Beek, I., Smets, E. M. A., Legdeur, M. A., de Hullu, J. A., Lok, C. A. R., Buist, M. R., Mourits, M. J. E., Kets, C. M., van der Kolk, L. E., Oosterwijk, J. C., Aalfs, C. M.

“…The new Dutch guidelines on hereditary and familial ovarian carcinoma recommend genetic testing of all patients with epithelial ovarian cancer (EOC). With this…”
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Prevalence and detection of psychosocial problems in cancer genetic counseling by Eijzenga, W., Bleiker, E. M. A., Hahn, D. E. E., Van der Kolk, L. E., Sidharta, G. N., Aaronson, N. K.

“…Only a minority of individuals who undergo cancer genetic counseling experience heightened levels of psychological distress, but many more experience a range…”
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Treatment of relapsed B-cell non-Hodgkin's lymphoma with a combination of chimeric anti-CD20 monoclonal antibodies (rituximab) and G-CSF: final report on safety and efficacy by VAN DER KOLK, L. E, GRILLO-LOPEZ, A. J, BAARS, J. W, VAN OERS, M. H. J

“…Antibody-dependent cellular cytotoxicity (ADCC) is one of the possible mechanisms of action of the chimeric CD20 monoclonal antibody IDEC-C2B8 (rituximab). As…”
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CD20-induced B cell death can bypass mitochondria and caspase activation by VAN DER KOLK, L. E, EVERS, L. M, OMENE, C, LENS, S. M. A, LEDERMAN, S, VAN LIER, R. A. W, VAN OERS, M. H. J, ELDERING, E

“…The apoptotic pathway activated by chimeric anti-CD20 monoclonal antibodies (rituximab, IDEC.C2B8) was analyzed using the Burkitt lymphoma cell line Ramos…”
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Routine assessment of psychosocial problems after cancer genetic counseling: results from a randomized controlled trial by Eijzenga, W., Bleiker, E.M.A., Ausems, M.G.E.M., Sidharta, G.N., Van der Kolk, L.E., Velthuizen, M.E., Hahn, D.E.E., Aaronson, N.K.

“…Approximately 70% of counselees undergoing cancer genetic counseling and testing (CGCT) experience some degree of CGCT‐related psychosocial problems. We…”
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Analysis of CD20-dependent cellular cytotoxicity by G-CSF-stimulated neutrophils by VAN DER KOLK, L. E, DE HAAS, M, GRILLO-LOPEZ, A. J, BAARS, J. W, VAN OERS, M. H. J

“…Rituximab, a chimeric CD20 monoclonal antibody (mAb), is widely used in the treatment of patients with low-grade non-Hodgkin's lymphoma. Possible anti-tumour…”
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Update on the Sentinel Node Procedure in Vulvar Cancer by van der Kolk, Willemijn L, Bart, Joost, van der Zee, Ate J G, Oonk, Maaike H M

“…Early-stage vulvar cancer is managed by a local excision of the primary tumor and, if indicated, a sentinel node (SN) biopsy to assess the need for further…”
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Unilateral inguinofemoral lymphadenectomy in patients with early-stage vulvar squamous cell carcinoma and a unilateral metastatic sentinel lymph node is safe by Van der Kolk, W.L., Van der Zee, A.G.J., Slomovitz, B.M., Baldwin, P.J.W., Van Doorn, H.C., De Hullu, J.A., Van der Velden, J., Gaarenstroom, K.N., Slangen, B.F.M., Kjolhede, P., Brännström, M., Vergote, I., Holland, C.M., Coleman, R., Van Dorst, E.B.L., Van Driel, W.J., Nunns, D., Widschwendter, M., Nugent, D., DiSilvestro, P.A., Mannel, R.S., Tjiong, M.Y., Boll, D., Cibula, D., Covens, A., Provencher, D., Runnebaum, I.B., Monk, B.J., Zanagnolo, V., Tamussino, K., Oonk, M.H.M., Levenback, C.F., Hermans, R.H., Bouda, J., Sharma, A., Luesley, D., Ellis, P., Cruickshank, D.J., Duncan, T.J., Kieser, K., Palle, C., Spirtos, N.M., O'Malley, D.M., Leitao, M.M., Geller, M., Dhar, K., Asher, V., Tobias, D.H., Borgfeldt, C., Lea, J.S., Lood, M., Bailey, J., Eyjolfsdottir, B., Attard-Montalto, S., Tewari, K.S., Persson, P., Manchanda, R., Jensen, P., Van Le, L.

“…OBJECTIVEOptimal management of the contralateral groin in patients with early-stage vulvar squamous cell carcinoma (VSCC) and a metastatic unilateral inguinal…”
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Bilateral Renal Tumour as Indicator for Birt-Hogg-Dubé Syndrome by Johannesma, P. C., van Moorselaar, R. J. A., Horenblas, S., van der Kolk, L. E., Thunnissen, E., van Waesberghe, J. H. T. M., Menko, F. H., Postmus, P. E.

“…Birt-Hogg-Dubé (BHD) syndrome is a cancer disorder caused by a pathogenic FLCN mutation characterized by fibrofolliculomas, lung cysts, pneumothorax, benign…”
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1673P Exploring different strategies to incorporate germline analysis in tumor whole genome sequencing by Koster, R., Schipper, L., van Beek, D., Mendeville, M., Samsom, K., Rosenberg, E.H., Hogervorst, F., Roepman, P., Meijer, G., Voest, E.E., van Wezel, T., van der Kolk, L., Monkhorst, K.

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1189O Validation of whole genome sequencing in routine clinical practice by Monkhorst, K., Samsom, K., Schipper, L., Roepman, P., Bosch, L., de Bruijn, E., Hoes, L.R., Riethorst, I., Schoenmaker, L., van der Kolk, L., Buffart, T., van der Hoeven, K., Voest, E.E., Cuppen, E., Meijer, G.

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1408P - WGS implementation in standard cancer diagnostics for every cancer patient (WIDE) by Roepman, P., Bosch, L., Samsom, K., Schipper, L., de Bruijn, E., Hoes, L., Riethorst, I., Schoenmaker, L., van der Kolk, L., van Snellenberg, H., Voest, E.E., Cuppen, E., Monkhorst, K., Meijer, G.

“…Advances in DNA sequencing technology have strongly reduced costs of Whole Genome Sequencing (WGS) and have made it possible to perform WGS on tumor biopsies…”
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1408PWGS implementation in standard cancer diagnostics for every cancer patient (WIDE) by Roepman, P, Bosch, L, Samsom, K, Schipper, L, de Bruijn, E, Hoes, L, Riethorst, I, Schoenmaker, L, van der Kolk, L, van Snellenberg, H, Voest, E E, Cuppen, E, Monkhorst, K, Meijer, G

“…Abstract Background Advances in DNA sequencing technology have strongly reduced costs of Whole Genome Sequencing (WGS) and have made it possible to perform WGS…”
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WGS implementation in standard cancer diagnostics for every cancer patient (WIDE) by Roepman, P., Bosch, L., Samsom, K., Schipper, L., de Bruijn, E., Hoes, L., Riethorst, I., Schoenmaker, L., van der Kolk, L., van Snellenberg, H., Voest, E.E., Cuppen, E., Monkhorst, K., Meijer, G.

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The PCQ-Infertility Revised: A New Digital Instrument to Measure Treatment Satisfaction of Fertility Patients by van der Kolk, Lotte, Smit, Ellen, Bloemer, Josée, van Wijk, Lise Marit

“…One of the key dimensions of healthcare quality is patient-centeredness, which represents how well healthcare is geared towards patients' needs and wishes…”
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