Search Results - "Kolijn, Detmar"

Validation of Foot Placement Locations from Ankle Data of a Kinect v2 Sensor by Geerse, Daphne, Coolen, Bert, Kolijn, Detmar, Roerdink, Melvyn

“…The Kinect v2 sensor may be a cheap and easy to use sensor to quantify gait in clinical settings, especially when applied in set-ups integrating multiple…”
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Diastolic dysfunction is initiated by cardiomyocyte impairment ahead of endothelial dysfunction due to increased oxidative stress and inflammation in an experimental prediabetes model by Waddingham, Mark T., Sonobe, Takashi, Tsuchimochi, Hirotsugu, Edgley, Amanda J., Sukumaran, Vijayakumar, Chen, Yi Ching, Hansra, Sarabjit S., Schwenke, Daryl O., Umetani, Keiji, Aoyama, Kohki, Yagi, Naoto, Kelly, Darren J., Gaderi, Shahrooz, Herwig, Melissa, Kolijn, Detmar, Mügge, Andreas, Paulus, Walter J., Ogo, Takeshi, Shirai, Mikiyasu, Hamdani, Nazha, Pearson, James T.

“…Coronary microvessel endothelial dysfunction and nitric oxide (NO) depletion contribute to elevated passive tension of cardiomyocytes, diastolic dysfunction…”
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Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator by Kolijn, Detmar, Kovács, Árpád, Herwig, Melissa, Lódi, Mária, Sieme, Marcel, Alhaj, Abdulatif, Sandner, Peter, Papp, Zoltán, Reusch, Peter H, Haldenwang, Peter, Falcão-Pires, Ines, Linke, Wolfgang A, Jaquet, Kornelia, Van Linthout, Sophie, Mügge, Andreas, Tschöpe, Carsten, Hamdani, Nazha

“…Our aim was to investigate the effect of nitric oxide (NO)-independent activation of soluble guanylyl cyclase (sGC) on cardiomyocyte function in a hypertensive…”
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Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D by Herwig, Melissa, Kolijn, Detmar, Lódi, Mária, Hölper, Soraya, Kovács, Árpád, Papp, Zoltán, Jaquet, Kornelia, Haldenwang, Peter, Dos Remedios, Cris, Reusch, Peter H, Mügge, Andreas, Krüger, Marcus, Fielitz, Jens, Linke, Wolfgang A, Hamdani, Nazha

“…The giant protein titin performs structure-preserving functions in the sarcomere and is important for the passive stiffness (F ) of cardiomyocytes. Protein…”
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The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts by Budde, Heidi, Hassoun, Roua, Tangos, Melina, Zhazykbayeva, Saltanat, Herwig, Melissa, Varatnitskaya, Marharyta, Sieme, Marcel, Delalat, Simin, Sultana, Innas, Kolijn, Detmar, Gömöri, Kamilla, Jarkas, Muhammad, Lódi, Mária, Jaquet, Kornelia, Kovács, Árpád, Mannherz, Hans Georg, Sequeira, Vasco, Mügge, Andreas, Leichert, Lars I., Sossalla, Samuel, Hamdani, Nazha

“…Oxidative stress is defined as an imbalance between the antioxidant defense system and the production of reactive oxygen species (ROS). At low levels, ROS are…”
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Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart by Kovács, Árpád, Herwig, Melissa, Budde, Heidi, Delalat, Simin, Kolijn, Detmar, Bódi, Beáta, Hassoun, Roua, Tangos, Melina, Zhazykbayeva, Saltanat, Balogh, Ágnes, Czuriga, Dániel, Van Linthout, Sophie, Tschöpe, Carsten, Dhalla, Naranjan S., Mügge, Andreas, Tóth, Attila, Papp, Zoltán, Barta, Judit, Hamdani, Nazha

“…Standard heart failure (HF) therapies have failed to improve cardiac function or survival in HF patients with right ventricular (RV) dysfunction suggesting a…”
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Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation by Kolijn, Detmar, Pabel, Steffen, Tian, Yanna, Lódi, Mária, Herwig, Melissa, Carrizzo, Albino, Zhazykbayeva, Saltanat, Kovács, Árpád, Fülöp, Gábor Á, Falcão-Pires, Inês, Reusch, Peter H, Linthout, Sophie Van, Papp, Zoltán, van Heerebeek, Loek, Vecchione, Carmine, Maier, Lars S, Ciccarelli, Michele, Tschöpe, Carsten, Mügge, Andreas, Bagi, Zsolt, Sossalla, Samuel, Hamdani, Nazha

“…Abstract Aims Sodium-glucose-cotransporter-2 inhibitors showed favourable cardiovascular outcomes, but the underlying mechanisms are still elusive. This study…”
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Methylation of the Hippo effector YAP by the methyltransferase SETD7 drives myocardial ischaemic injury: a translational study by Ambrosini, Samuele, Montecucco, Fabrizio, Kolijn, Detmar, Pedicino, Daniela, Akhmedov, Alexander, Mohammed, Shafeeq A, Herwig, Melissa, Gorica, Era, Szabó, Petra L, Weber, Lukas, Russo, Giulio, Vinci, Ramona, Matter, Christian M, Liuzzo, Giovanna, Brown, Peter J, Rossi, Fabio M V, Camici, Giovanni G, Sciarretta, Sebastiano, Beltrami, Antonio P, Crea, Filippo, Podesser, Bruno, Lüscher, Thomas F, Kiss, Attila, Ruschitzka, Frank, Hamdani, Nazha, Costantino, Sarah, Paneni, Francesco

“…Methylation of non-histone proteins is emerging as a central regulatory mechanism in health and disease. The methyltransferase SETD7 has shown to methylate and…”
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Abstract 10477: Targeting the Methyltransferase Setd7 Prevents Myocardial Ischemic Injury: A Translational Study by Ambrosini, Samuele, Montecucco, Fabrizio, Kolijn, Detmar, Akhmedov, Alexander, Pedicino, Daniela, Mohammed, Shafeeq Ahmed, Kiss, Attila, Beltrami, Antonio Paolo P, crea, Filippo, Luescher, Thomas F, Hamdani, Nazha, Costantino, Sarah, Paneni, Francesco

“…IntroductionDespite appropriate revascularization strategies, a significant number of patients with myocardial infarction (MI) develop ischemic heart failure…”
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SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress by Tangos, Melina, Budde, Heidi, Kolijn, Detmar, Sieme, Marcel, Zhazykbayeva, Saltanat, Lódi, Mária, Herwig, Melissa, Gömöri, Kamilla, Hassoun, Roua, Robinson, Emma Louise, Meister, Toni Luise, Jaquet, Kornelia, Kovács, Árpád, Mustroph, Julian, Evert, Katja, Babel, Nina, Fagyas, Miklós, Lindner, Diana, Püschel, Klaus, Westermann, Dirk, Mannherz, Hans Georg, Paneni, Francesco, Pfaender, Stephanie, Tóth, Attila, Mügge, Andreas, Sossalla, Samuel, Hamdani, Nazha

“…The respiratory illness triggered by severe acute respiratory syndrome virus-2 (SARS-CoV-2) is often particularly serious or fatal amongst patients with…”
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Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase by Stadhouders, Lian E.M., Smith, Jonathon A.B., Gabriel, Brendan M., Verbrugge, Sander A.J., Hammersen, Tim D., Kolijn, Detmar, Vogel, Ilse S.P., Mohamed, Abdalla D., de Wit, Gerard M.J., Offringa, Carla, Hoogaars, Willem M.H., Gehlert, Sebastian, Wackerhage, Henning, Jaspers, Richard T.

“…The Warburg effect links growth and glycolysis in cancer. A key purpose of the Warburg effect is to generate glycolytic intermediates for anabolic reactions,…”
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