Search Results - "Koletzki, D"
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P739 RISK FACTORS AND TREATMENT OUTCOMES IN GENOTYPE 1 AND GENOTYPE 4 HEPATITIS C INFECTED PATIENTS FROM A REAL WORLD DATA ANALYSIS IN EUROPE
Published in Journal of hepatology (01-04-2014)Get full text
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Mapping of B-cell epitopes in the nucleocapsid protein of Puumala hantavirus
Published in Viral immunology (01-01-2002)“…Hantavirus nucleocapsid protein (N) has been proven to induce highly protective immune responses in animal models. The knowledge on the mechanisms behind…”
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DNA vaccination of mice with a plasmid encoding Puumala hantavirus nucleocapsid protein mimics the B-cell response induced by virus infection
Published in Journal of biotechnology (17-11-2000)“…Inoculation of naked DNA has been applied for the development of prophylactic and therapeutic vaccines against different viral infections. To study the humoral…”
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New chimaeric hepatitis B virus core particles carrying hantavirus (serotype Puumala) epitopes: immunogenicity and protection against virus challenge
Published in Journal of biotechnology (20-08-1999)“…Virus-like particles generated by the heterologous expression of virus structural proteins are able to potentiate the immunogenicity of foreign epitopes…”
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HBV core particles allow the insertion and surface exposure of the entire potentially protective region of Puumala hantavirus nucleocapsid protein
Published in Biological chemistry (01-03-1999)“…Core particles of the hepatitis B virus (HBV) potentiate the immune response against foreign epitopes presented on their surface. Potential insertion sites in…”
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Mosaic hepatitis B virus core particles allow insertion of extended foreign protein segments
Published in Journal of general virology (01-08-1997)“…D Koletzki, A Zankl, HR Gelderblom, H Meisel, A Dislers, G Borisova, P Pumpens, DH Kruger and R Ulrich Institute of Medical Virology, Charite,…”
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Characterization of potential insertion sites in the core antigen of hepatitis B virus by the use of a short-sized model epitope
Published in Intervirology (01-01-1999)“…Core particles of hepatitis B virus (HBV) are able to improve the immunogenicity of foreign sequences exposed on the particle surface. The insertion site in…”
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Puumala (PUU) Hantavirus Strain Differences and Insertion Positions in the Hepatitis B Virus Core Antigen Influence B-cell Immunogenicity and Protective Potential of Core-Derived Particles
Published in Virology (New York, N.Y.) (25-10-2000)“…Hepatitis B virus (HBV) core-derived chimeric particles carrying a Puumala (PUU) hantavirus (strain Vranica/Hällnäs) nucleocapsid (N) protein sequence (aa…”
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DNA vaccination of mice with a plasmid encoding Puumala hantavirus nucleocapsid protein mimics the B-cell response induced by virus infection
Published in Journal of biotechnology (17-11-2001)“…Inoculation of naked DNA has been applied for the development of prophylactic and therapeutic vaccines against different viral infections. To study the humoral…”
Get full text
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Chimaeric HBV core particles carrying a defined segment of Puumala hantavirus nucleocapsid protein evoke protective immunity in an animal model
Published in Vaccine (01-01-1998)“…Hantaviruses are rodent-born agents which are pathogenic in humans causing haemorrhagic fever with renal syndrome or hantavirus pulmonary syndrome. To induce a…”
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Stop codon insertion restores the particle formation ability of hepatitis B virus core-hantavirus nucleocapsid protein fusions
Published in Intervirology (2002)“…In recent years, epitopes of various origin have been inserted into the core protein of hepatitis B virus (HBc), allowing the formation of chimeric HBc…”
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