Search Results - "Kolesar, G B"

Toxicology and Humoral Immunity Assessment of Octamethylcyclotetrasiloxane (D4) Following a 28-day whole body Vapor Inhalation Exposure in Fischer 344 Rats by Klykken, P. C., Galbraith, T. W., Kolesar, G. B., Jean, P. A., Woolhiser, M. R., Elwell, M. R., Burns-Naas, L. A., Mast, R. W., Mccay, J. A., White Jr, K. L., Munson, A. E.

“…ABSTRACT Octamethylcyclotetrasiloxane, D4, is a low viscosity, silicone fluid consisting of four dimethyl-siloxy units ((CH3)2SiO)4 in a cyclic structure. It…”
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Repeated Inhalation Exposure to Octamethylcyclotetrasiloxane Produces Hepatomegaly, Transient Hepatic Hyperplasia, and Sustained Hypertrophy in Female Fischer 344 Rats in a Manner Similar to Phenobarbital by McKim, James M., Kolesar, Gary B., Jean, Paul A., Meeker, Linda S., Wilga, Paul C., Schoonhoven, Robert, Swenberg, James A., Goodman, Jay I., Gallavan, Robert H., Meeks, Robert G.

“…Octamethylcyclotetrasiloxane (D4) has been described as a phenobarbital-like inducer of hepatic enzymes. Phenobarbital (PB) and phenobarbital-like chemicals…”
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Evaluation of octamethylcyclotetrasiloxane (D4) as an inducer of rat hepatic microsomal cytochrome P450, UDP-glucuronosyltransferase, and epoxide hydrolase: a 28-day inhalation study by McKim, Jr, J M, Wilga, P C, Kolesar, G B, Choudhuri, S, Madan, A, Dochterman, L W, Breen, J G, Parkinson, A, Mast, R W, Meeks, R G

“…Repeated inhalation exposure to octamethylcyclotetrasiloxane (D4) produces a reversible and dose-related hepatomegaly and proliferation of hepatic endoplasmic…”
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Hexamethyldisiloxane: A 13-Week Subchronic Whole-Body Vapor Inhalation Toxicity Study in Fischer 344 Rats by Cassidy, Simon L., Dotti, Antonio, Kolesar, Gary B., Dochterman, L. Wayne, Meeks, Robert G., Chevalier, H. J.

“…Hexamethyldisiloxane (HMDS) is a volatile linear siloxane dimer used in many applications, including precision cleaning, active ingredient carrier, and as a…”
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Subchronic inhalation toxicity of tetramethoxysilane in rats by Kolesar, G B, Siddiqui, W H, Geil, R G, Malczewski, R M, Hobbs, E J

“…Sprague-Dawley rats were exposed 6 hr/day, 5 days a week, for 28 days to tetramethoxysilane (TMOS) at concentrations of 0, 1, 5, and 10 ppm (Phase I study) and…”
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Subchronic inhalation toxicity of 1,1,1,3-tetrachloropropane in rats by Kolesar, G B, Siddiqui, W H, Crofoot, S D, Evans, M G, Meeks, R G

“…The purpose of this study was to evaluate the inhalation toxicity of 1,1,1,3-tetrachloropropane (TCP), an intermediate in the production of chlorinated…”
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Chlorosilane Acute Inhalation Toxicity and Development of an LC50 Prediction Model by Jean, Paul A., Gallavan, Robert H., Kolesar, Gary B., Siddiqui, Waheed H., Oxley, Jon A., Meeks, Robert G.

“…The acute inhalation toxicity of 10 chlorosilanes was investigated in Fischer 344 rats using a 1-h whole-body vapor inhalation exposure and a 14-day recovery…”
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Hexamethyidisiloxane: A 13-week subchronic whole-body vapor inhalation toxicity study in Fischer 344 rats by Cassidy, S L, Dotti, A, Kolesar, G B, Dochterman, L W, Meeks, R G, Chevalier, H J

“…Hexamethyldisiloxane (HMDS) is a volatile linear siloxane dimer used in many applications, including precision cleaning, active ingredient carrier, and as a…”
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Inhalation Toxicology of Octamethylcyclotetrasiloxane (D sub(4)) Following a 3-Month Nose-Only Exposure in Fischer 344 Rats by Burns-Naas, LA, Meeks, R G, Kolesar, G B, Mast, R W, Elwell, M R, Hardisty, J F, Thevenaz, P

“…Octamethylcyclotetrasiloxane (D sub(4)) is a low-molecular-weight cyclic siloxane used primarily in the synthesis of silicone polymers. The objective of the…”
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Inhalation Toxicology of Octamethylcyclotetrasiloxane (D4) Following a 3-Month Nose-Only Exposure in Fischer 344 Rats by Burns-Naas, Leigh Ann, Meeks, Robert G., Kolesar, Gary B., Mast, Richard W., Elwell, Michael R., Hardisty, Jerry F., Thevenaz, Philippe

“…Octamethylcyclotetrasiloxane (D4) is a low-molecular-weight cyclic siloxane used primarily in the synthesis of silicone polymers. The objective of the present…”
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