Search Results - "Kolendowski, Bart"

Gain-of-function p53R175H blocks apoptosis in a precursor model of ovarian high-grade serous carcinoma by Haagsma, Jacob, Kolendowski, Bart, Buensuceso, Adrian, Valdes, Yudith Ramos, DiMattia, Gabriel E., Shepherd, Trevor G.

“…Ovarian high-grade serous carcinoma (HGSC) is a highly lethal malignancy for which early detection is a challenge and treatment of late-stage disease is…”
Get full text

Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex by Hassan, Haider M., Kolendowski, Bart, Isovic, Majdina, Bose, Kerstin, Dranse, Helen J., Sampaio, Arthur V., Underhill, T. Michael, Torchia, Joseph

“…Retinoic acid (RA) plays important roles in development, growth, and homeostasis through regulation of the nuclear receptors for RA (RARs). Herein, we identify…”
Get full text

Isoform-specific promotion of breast cancer tumorigenicity by TBX3 involves induction of angiogenesis by Krstic, Milica, Hassan, Haider M., Kolendowski, Bart, Hague, M. Nicole, Anborgh, Pieter. H., Postenka, Carl O., Torchia, Joseph, Chambers, Ann F., Tuck, Alan B.

“…TBX3 is a member of the highly conserved family of T-box transcription factors involved in embryogenesis, organogenesis and tumor progression. While the…”
Get full text

Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma by Hassan, Haider M., Isovic, Majdina, Kolendowski, Bart, Bauer-Maison, Natasha, Onabote, Oladapo, Cecchini, Matthew, Haig, Aaron, Maleki Vareki, Saman, Underhill, T. Michael, Torchia, Joseph

“…Thymine DNA glycosylase (TDG) is a nuclear receptor coactivator that plays an essential role in the maintenance of epigenetic stability in cells. Here, we…”
Get full text

Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization by Kolendowski, Bart, Hassan, Haider, Krstic, Milica, Isovic, Majdina, Thillainadesan, Gobi, Chambers, Ann F, Tuck, Alan B, Torchia, Joseph

“…The estrogen receptor (ER) is a ligand-dependant transcription factor expressed in many breast cancers and is the target of many endocrine-based cancer…”
Get full text

Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C by Kolendowski, Bart, Valdes, Yudith Ramos, Hirte, Hal, Itamochi, Hiroaki, Lee, Wonjae, Carey, Mark, Shepherd, Trevor G, DiMattia, Gabriel E

“…Ovarian clear cell carcinoma (OCCC) is a rare subtype of gynecological cancer for which well-characterized and authenticated model systems are scarce. We…”
Get full text

TBX3 promotes progression of pre‐invasive breast cancer cells by inducing EMT and directly up‐regulating SLUG by Krstic, Milica, Kolendowski, Bart, Cecchini, Matthew J, Postenka, Carl O, Hassan, Haider M, Andrews, Joseph, MacMillan, Connor D, Williams, Karla C, Leong, Hon S, Brackstone, Muriel, Torchia, Joseph, Chambers, Ann F, Tuck, Alan B

“…The acquisition of cellular invasiveness by breast epithelial cells and subsequent transition from ductal carcinoma in situ (DCIS) to invasive breast cancer is…”
Get full text

Gain-of-function p53 R175H blocks apoptosis in a precursor model of ovarian high-grade serous carcinoma by Haagsma, Jacob, Kolendowski, Bart, Buensuceso, Adrian, Valdes, Yudith Ramos, DiMattia, Gabriel E, Shepherd, Trevor G

“…Ovarian high-grade serous carcinoma (HGSC) is a highly lethal malignancy for which early detection is a challenge and treatment of late-stage disease is…”
Get full text

The Role of Thymine-Dna Glycosylase in Transcriptional Regulation by Kolendowski, Bart

“…Precise control over transcriptional regulation is required for normal cell function. Errors in transcriptional regulation underpin many diseases including…”
Get full text

Human papillomavirus dysregulates the cellular apparatus controlling the methylation status of H3K27 in different human cancers to consistently alter gene expression regardless of tissue of origin by Gameiro, Steven F, Kolendowski, Bart, Zhang, Ali, Barrett, John W, Nichols, Anthony C, Torchia, Joe, Mymryk, Joe S

“…High-risk human papillomaviruses (HPV) cause cancer at multiple distinct anatomical locations. Regardless of the tissue of origin, most HPV positive (HPV+)…”
Get full text