Search Results - "Kolenc Peitl, Petra"

Radiolabelled CCK2R Antagonists Containing PEG Linkers: Design, Synthesis and Evaluation by Novak, Doroteja, Tomašič, Tihomir, Krošelj, Marko, Javornik, Uroš, Plavec, Janez, Anderluh, Marko, Kolenc Peitl, Petra

“…The cholecystokinin‐2/gastrin receptor (CCK2R) is considered a suitable target for the development of radiolabelled antagonists, due to its overexpression in…”
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Superior Diagnostic Performance of the GLP-1 Receptor Agonist [Lys40(AhxHYNIC-[99mTc]/EDDA)NH2]-Exendin-4 over Conventional Imaging Modalities for Localization of Insulinoma by Senica, Katra, Tomazic, Ales, Skvarca, Ales, Kolenc Peitl, Petra, Mikolajczak, Renata, Hubalewska-Dydejczyk, Alicja, Lezaic, Luka

“…Purpose Insulinomas are the most common functioning neuroendocrine neoplasms of the pancreas, typically diagnosed due to characteristic symptoms. In the vast…”
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Current Status of Radiopharmaceuticals for the Theranostics of Neuroendocrine Neoplasms by Fani, Melpomeni, Peitl, Petra Kolenc, Velikyan, Irina

“…Nuclear medicine plays a pivotal role in the management of patients affected by neuroendocrine neoplasms (NENs). Radiolabeled somatostatin receptor analogs are…”
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Clinical translation of theranostic radiopharmaceuticals: Current regulatory status and recent examples by Kolenc Peitl, Petra, Rangger, Christine, Garnuszek, Piotr, Mikolajczak, Renata, Hubalewska‐Dydejczyk, Alicja, Maina, Theodosia, Erba, Paola, Decristoforo, Clemens

“…With the development of ever more radiopharmaceuticals suitable for theranostic applications, translation of novel compounds from the preclinical stage towards…”
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EANM guideline on the validation of analytical methods for radiopharmaceuticals by Gillings, Nic, Todde, Sergio, Behe, Martin, Decristoforo, Clemens, Elsinga, Philip, Ferrari, Valentina, Hjelstuen, Olaug, Peitl, Petra Kolenc, Koziorowski, Jacek, Laverman, Peter, Mindt, Thomas L., Ocak, Meltem, Patt, Marianne

“…Background To fulfil good manufacturing requirements, analytical methods for the analysis of pharmaceuticals for human and vetinary use must be validated. The…”
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Guideline on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals by Gillings, Nic, Hjelstuen, Olaug, Ballinger, Jim, Behe, Martin, Decristoforo, Clemens, Elsinga, Philip, Ferrari, Valentina, Peitl, Petra Kolenc, Koziorowski, Jacek, Laverman, Peter, Mindt, Thomas L., Neels, Oliver, Ocak, Meltem, Patt, Marianne, Todde, Sergio

“…This guideline on current good radiopharmacy practice (cGRPP) for small-scale preparation of radiopharmaceuticals represents the view of the Radiopharmacy…”
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CCK2R antagonists: from SAR to clinical trials by Novak, Doroteja, Anderluh, Marko, Kolenc Peitl, Petra

“…•The CCK2 receptor is involved in numerous (patho)physiological processes.•Many CCK2 receptor antagonists have shown promising results in in-vivo animal…”
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Stereochemistry of Amino Acid Spacers Determines the Pharmacokinetics of 111 In–DOTA–Minigastrin Analogues for Targeting the CCK2/Gastrin Receptor by Kolenc Peitl, Petra, Tamma, MariaLuisa, Kroselj, Marko, Braun, Friederike, Waser, Beatrice, Reubi, Jean Claude, Sollner Dolenc, Marija, Maecke, Helmut R., Mansi, Rosalba

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From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial by Pawlak, Dariusz, Rangger, Christine, Kolenc Peitl, Petra, Garnuszek, Piotr, Maurin, Michał, Ihli, Laura, Kroselj, Marko, Maina, Theodosia, Maecke, Helmut, Erba, Paola, Kremser, Leopold, Hubalewska-Dydejczyk, Alicja, Mikołajczak, Renata, Decristoforo, Clemens

“…A variety of radiolabelled minigastrin analogues targeting the cholecystokinin 2 (CCK2) receptor were developed and compared in a concerted preclinical testing…”
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Intracoronary Transplantation of CD34+ Cells Is Associated With Improved Myocardial Perfusion in Patients With Nonischemic Dilated Cardiomyopathy by Lezaic, Luka, MD, PhD, Socan, Aljaz, MPharm, Poglajen, Gregor, MD, PhD, Peitl, Petra Kolenc, MPharm, PhD, Sever, Matjaz, MD, Cukjati, Marko, MD, Cernelc, Peter, MD, PhD, Wu, Joseph C., MD, PhD, Haddad, François, MD, Vrtovec, Bojan, MD, PhD

“…Abstract Background We investigated the effects of intracoronary transplantation of CD34+ cells on myocardial perfusion in patients with nonischemic dilated…”
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A novel, self-shielded modular radiosynthesis system for fully automated preparation of PET and therapeutic radiopharmaceuticals by Kroselj, Marko, Socan, Aljaz, Zaletel, Katja, Dreger, Thorsten, Knopp, Roger, Gmeiner, Tanja, Kolenc Peitl, Petra

“…OBJECTIVEWith the vast development of theranostics and, recently, Ga-radiolabeled molecules, there is also a need for novel, smaller, flexible, safe, and…”
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Selection of the First 99mTc-Labelled Somatostatin Receptor Subtype 2 Antagonist for Clinical Translation—Preclinical Assessment of Two Optimized Candidates by Fani, Melpomeni, Weingaertner, Viktoria, Kolenc Peitl, Petra, Mansi, Rosalba, Gaonkar, Raghuvir H., Garnuszek, Piotr, Mikolajczak, Renata, Novak, Doroteja, Simoncic, Urban, Hubalewska-Dydejczyk, Alicja, Rangger, Christine, Kaeopookum, Piriya, Decristoforo, Clemens

“…Recently, radiolabelled antagonists targeting somatostatin receptors subtype 2 (SST2) in neuroendocrine neoplasms demonstrated certain superior properties over…”
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EANM guideline for the preparation of an Investigational Medicinal Product Dossier (IMPD) by Todde, Sergio, Windhorst, Albert D., Behe, Martin, Bormans, Guy, Decristoforo, Clemens, Faivre-Chauvet, Alain, Ferrari, Valentina, Gee, Antony D., Gulyas, Balazs, Halldin, Christer, Peitl, Petra Kolenc, Koziorowski, Jacek, Mindt, Thomas L., Sollini, Martina, Vercouillie, Johnny, Ballinger, James R., Elsinga, Philip H.

“…The preparation of an Investigational Medicinal Product Dossier (IMPD) for a radiopharmaceutical to be used in a clinical trial is a challenging proposition…”
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Guidance on current good radiopharmacy practice for the small-scale preparation of radiopharmaceuticals using automated modules: a European perspective by Aerts, Joel, Ballinger, James R., Behe, Martin, Decristoforo, Clemens, Elsinga, Philip H., Faivre-Chauvet, Alain, Mindt, Thomas L., Kolenc Peitl, Petra, Todde, Sergio C., Koziorowski, Jacek

“…This document is meant to complement Part B of the EANM ‘Guidelines on current good radiopharmacy practice (cGRPP) in the preparation of radiopharmaceuticals’…”
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Radiooznačeni peptidi v nuklearni medicini by Krošelj, Marko, Kolenc Peitl, Petra, Sočan, Aljaž, Leskovec, Marijana, Mlinarič-Raščan, Irena, Gmeiner, Tanja

“…Nuklearna medicina pri obravnavi onkoloških bolnikov omogoča slikovni prikaz oziroma lokalizacijo tumorjev, ciljano zdravljenje ter spremljanje uspešnosti…”
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CCK 2 R antagonists: from SAR to clinical trials by Novak, Doroteja, Anderluh, Marko, Kolenc Peitl, Petra

“…The widespread involvement of the cholecystokinin-2/gastrin receptor (CCK R) in multiple (patho)physiological processes has propelled extensive searches for…”
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Radiolabelled CCK 2 R Antagonists Containing PEG Linkers: Design, Synthesis and Evaluation by Novak, Doroteja, Tomašič, Tihomir, Krošelj, Marko, Javornik, Uroš, Plavec, Janez, Anderluh, Marko, Kolenc Peitl, Petra

“…The cholecystokinin-2/gastrin receptor (CCK R) is considered a suitable target for the development of radiolabelled antagonists, due to its overexpression in…”
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Stereochemistry of amino acid spacers determines the pharmacokinetics of (111)In-DOTA-minigastrin analogues for targeting the CCK2/gastrin receptor by Kolenc Peitl, Petra, Tamma, MariaLuisa, Kroselj, Marko, Braun, Friederike, Waser, Beatrice, Reubi, Jean Claude, Sollner Dolenc, Marija, Maecke, Helmut R, Mansi, Rosalba

“…The metabolic instability and high kidney retention of minigastrin (MG) analogues hamper their suitability for use in peptide-receptor radionuclide therapy of…”
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Imaging and 1-day kinetics of intracoronary stem cell transplantation in patients with idiopathic dilated cardiomyopathy by Lezaic, Luka, Socan, Aljaz, Peitl, Petra Kolenc, Poglajen, Gregor, Sever, Matjaz, Cukjati, Marko, Cernelc, Peter, Vrtovec, Bojan

“…Abstract Background Stem cell transplantation is an emerging method of treatment for patients with cardiovascular disease. There are few studies completed or…”
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Radiolabelled CCK2 R Antagonists Containing PEG Linkers: Design, Synthesis and Evaluation by Novak, Doroteja, Tomašič, Tihomir, Krošelj, Marko, Javornik, Uroš, Plavec, Janez, Anderluh, Marko, Kolenc Peitl, Petra

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