Search Results - "Koledova, Zuzana"
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Fibroblast-induced mammary epithelial branching depends on fibroblast contractility
Published in PLoS biology (10-01-2024)“…Epithelial branching morphogenesis is an essential process in living organisms, through which organ-specific epithelial shapes are created. Interactions…”
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Evolution and Self-renewal of the Journal of Mammary Gland Biology and Neoplasia
Published in Journal of mammary gland biology and neoplasia (01-09-2021)Get full text
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Unraveling the Breast: Advances in Mammary Biology and Cancer Methods
Published in Journal of mammary gland biology and neoplasia (01-12-2020)“…The field of mammary gland biology and breast cancer research encompasses a wide range of topics and scientific questions, which span domains of molecular,…”
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Mammary Organoids and 3D Cell Cultures: Old Dogs with New Tricks
Published in Journal of mammary gland biology and neoplasia (01-12-2020)“…3D cell culture methods have been an integral part of and an essential tool for mammary gland and breast cancer research for half a century. In fact, mammary…”
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SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling
Published in Proceedings of the National Academy of Sciences - PNAS (27-09-2016)“…The role of the local microenvironment in influencing cell behavior is central to both normal development and cancer formation. Here, we show that sprouty 1…”
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3D Cell Culture Models Demonstrate a Role for FGF and WNT Signaling in Regulation of Lung Epithelial Cell Fate and Morphogenesis
Published in Frontiers in cell and developmental biology (21-07-2020)“…FGF signaling plays an essential role in lung development, homeostasis, and regeneration. We employed mouse 3D cell culture models and imaging to study the…”
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Connecting the Dots: Mammary Gland and Breast Cancer at Single Cell Resolution
Published in Journal of mammary gland biology and neoplasia (01-03-2021)Get full text
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Primary Mammary Organoid Model of Lactation and Involution
Published in Frontiers in cell and developmental biology (19-03-2020)“…Mammary gland development occurs mainly after birth and is composed of three successive stages: puberty, pregnancy and lactation, and involution. These…”
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FGF ligands of the postnatal mammary stroma regulate distinct aspects of epithelial morphogenesis
Published in Development (Cambridge) (01-09-2014)“…FGF signaling is essential for mammary gland development, yet the mechanisms by which different members of the FGF family control stem cell function and…”
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Fabrication of customized open-cell titanium foams by direct foaming for biomedical applications
Published in Journal of materials research and technology (01-11-2024)“…Titanium (Ti) foams offer a promising alternative for bone reconstruction and repair due to their high porosity and lower stiffness compared to solid metals,…”
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Fibroblast Growth Factor 2 Protein Stability Provides Decreased Dependence on Heparin for Induction of FGFR Signaling and Alters ERK Signaling Dynamics
Published in Frontiers in cell and developmental biology (12-12-2019)“…Fibroblast growth factor 2 (FGF2) plays important roles in tissue development and repair. Using heparan sulfates (HS)/heparin as a cofactor, FGF2 binds to FGF…”
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European Network of Breast Development and Cancer turned 10 years: a growing family of mammary gland researchers
Published in Breast cancer research : BCR (04-09-2018)“…The European Network for Breast Development and Cancer (ENBDC), a worldwide network ( http://www.enbdc.org/ ), celebrated its tenth anniversary with a…”
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A Robust Mammary Organoid System to Model Lactation and Involution-like Processes
Published in Bio-protocol (20-04-2021)“…The mammary gland is a highly dynamic tissue that changes throughout reproductive life, including growth during puberty and repetitive cycles of pregnancy and…”
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Editorial: Perspectives in Mammary Gland Development and Breast Cancer Research
Published in Frontiers in cell and developmental biology (25-08-2020)Get full text
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Cdk2 inhibition prolongs G1 phase progression in mouse embryonic stem cells
Published in Stem cells and development (01-02-2010)“…Embryonic stem cells (ESCs) proliferate rapidly and have a unique cell-cycle structure with a very short G1 phase. Previous reports suggested that the rapid G1…”
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3D Cell Culture: An Introduction
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2017)“…3D cell culture is an invaluable tool in developmental, cell, and cancer biology. By mimicking crucial features of in vivo environment, including cell-cell and…”
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FGF signaling in mammary gland fibroblasts regulates multiple fibroblast functions and mammary epithelial morphogenesis
Published in Development (Cambridge) (01-12-2019)“…ABSTRACT Fibroblast growth factor (FGF) signaling is crucial for mammary gland development. Although multiple roles for FGF signaling in the epithelium have…”
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3D Coculture of Mammary Organoids with Fibrospheres: A Model for Studying Epithelial-Stromal Interactions During Mammary Branching Morphogenesis
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…Mammary gland is composed of branched epithelial structure embedded within a complex stroma formed by several stromal cell types, including fibroblasts, and…”
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A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…The mammary gland consists of numerous tissue compartments, including mammary epithelium, an array of stromal cells, and the extracellular matrix (ECM)…”
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3D Cell Culture: Techniques For and Beyond Organoid Applications
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…In the rapidly evolving landscape of cell biology and biomedical research, three-dimensional (3D) cell culture has contributed not only to the diversification…”
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