Search Results - "Kole, Denis"

Collagen tethering of synthetic human antimicrobial peptides cathelicidin LL37 and its effects on antimicrobial activity and cytotoxicity by Lozeau, Lindsay D., Grosha, Jonian, Kole, Denis, Prifti, Fioleda, Dominko, Tanja, Camesano, Terri A., Rolle, Marsha W.

“…[Display omitted] Wound infections, particularly of chronic wounds, pose a substantial challenge for designing antimicrobial dressings that are both effective…”
Get full text

High molecular weight FGF2 isoforms demonstrate canonical receptor-mediated activity and support human embryonic stem cell self-renewal by Kole, Denis, Grella, Alexandra, Dolivo, David, Shumaker, Lucia, Hermans, William, Dominko, Tanja

“…Basic fibroblast growth factor (FGF2) is a highly pleiotropic member of a large family of growth factors with a broad range of activities, including…”
Get full text

Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells by Ambady, Sakthikumar, Malcuit, Christopher, Kashpur, Olga, Kole, Denis, Holmes, William F, Hedblom, Emmett, Page, Raymond L, Dominko, Tanja

“…The transcription factor NANOG is essential for maintaining pluripotency in embryonic stem cells. We have previously reported the expression of NANOG in adult…”
Get full text

FGF2 Overrides TGFβ1-Driven Integrin ITGA11 Expression in Human Dermal Fibroblasts by Grella, Alexandra, Kole, Denis, Holmes, William, Dominko, Tanja

“…ABSTRACT Deposition of collagen‐based extracellular matrix by fibroblasts during wound healing leads to scar formation—a typical outcome of the healing process…”
Get full text

Vimentin intermediate filaments modulate cell traction force but not cell sensitivity to substrate stiffness by Ho Thanh, Minh‐Tri, Grella, Alexandra, Kole, Denis, Ambady, Sakthikumar, Wen, Qi

“…The ability of cells to sense and respond to the mechanical stiffness of the surrounding matrix is important to support normal cell function, wound healing,…”
Get full text

FGF2 Overrides TGF[beta]1-Driven Integrin ITGA11 Expression in Human Dermal Fibroblasts by Grella, Alexandra, Kole, Denis, Holmes, William, Dominko, Tanja

“…Deposition of collagen-based extracellular matrix by fibroblasts during wound healing leads to scar formation--a typical outcome of the healing process in soft…”
Get full text

Induction of stem cell gene expression in adult human fibroblasts without transgenes by Page, Raymond L, Ambady, Sakthikumar, Holmes, William F, Vilner, Lucy, Kole, Denis, Kashpur, Olga, Huntress, Victoria, Vojtic, Ina, Whitton, Holly, Dominko, Tanja

“…Reprogramming of differentiated somatic cells into induced pluripotent stem (iPS) cells has potential for derivation of patient-specific cells for therapy as…”
Get more information

Maintenance of multipotency in human dermal fibroblasts treated with Xenopus laevis egg extract requires exogenous fibroblast growth factor-2 by Kole, Denis, Ambady, Sakthikumar, Page, Raymond L, Dominko, Tanja

“…Direct reprogramming of a differentiated somatic cell into a developmentally more plastic cell would offer an alternative to applications in regenerative…”
Get more information

Activity and toxicity of a recombinant LL37 antimicrobial peptide by Lindsay, Lozeau, Denis, Kole, Tanja, Dominko, Marsha, Rolle, Terri, Camesano

“…Abstract only…”
Get full text

Rational protein engineering in action: The first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus by Evdokimov, Artem G., Mekel, Marlene, Hutchings, Kim, Narasimhan, Lakshmi, Holler, Tod, McGrath, Teresa, Beattie, Bryan, Fauman, Eric, Yan, Chunhong, Heaslet, Holly, Walter, Richard, Finzel, Barry, Ohren, Jeffrey, McConnell, Patrick, Braden, Timothy, Sun, Fang, Spessard, Cindy, Banotai, Craig, Al-Kassim, Loola, Ma, Weijun, Wengender, Paul, Kole, Denis, Garceau, Norman, Toogood, Peter, Liu, Jia

“…In this article, we describe for the first time the high-resolution crystal structure of a phenylalanine tRNA synthetase from the pathogenic bacterium…”
Get full text

FGF2 and oxygen: Regulators of intergrin alpha-11 and extracellular matrix molecules by Grella, Alexandra, Kole, Denis, Dominko, Tanja

“…Recently, derivation and maintenance of pluripotent stem cells has been focused on environmental cues, with emphasis on the role of extracellular matrix (ECM)…”
Get full text