Search Results - "Koldej, Rachel M"

T Cell Fitness and Autologous CAR T Cell Therapy in Haematologic Malignancy by Mehta, Palak H, Fiorenza, Salvatore, Koldej, Rachel M, Jaworowski, Anthony, Ritchie, David S, Quinn, Kylie M

“…A range of emerging therapeutic approaches for the treatment of cancer aim to induce or augment endogenous T cell responses. Chimeric antigen receptor (CAR) T…”
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Association between P2X7 Polymorphisms and Post-Transplant Outcomes in Allogeneic Haematopoietic Stem Cell Transplantation by Koldej, Rachel M, Perera, Travis, Collins, Jenny, Ritchie, David S

“…Allogeneic stem cell transplantation (alloSCT) is a highly effective treatment method for haematologic malignancies. However, infection of acute organ…”
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Ibrutinib protects T cells in patients with CLL from proliferation-induced senescence by Davis, Joanne E, Sharpe, Chia, Mason, Kylie, Tam, Constantine S, Koldej, Rachel M, Ritchie, David S

“…The development of Bruton's tyrosine kinase inhibitors (BTKi) for the treatment of chronic lymphocytic leukaemia (CLL) has provided a highly effective and…”
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Dissection of the bone marrow microenvironment in hairy cell leukaemia identifies prognostic tumour and immune related biomarkers by Koldej, Rachel M., Prabahran, Ashvind, Tan, Chin Wee, Ng, Ashley P., Davis, Melissa J., Ritchie, David S.

“…Hairy cell leukaemia (HCL) is a rare CD20+ B cell malignancy characterised by rare “hairy” B cells and extensive bone marrow (BM) infiltration. Frontline…”
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Spatial proteomics identifies a spectrum of immune dysregulation in acquired bone marrow failure syndromes by Koldej, Rachel M., Prabahran, Ashvind, Tan, Chin Wee, Ludford-Menting, Mandy, Morgan, Huw, Holzwart, Nicholas, Davis, Melissa J., Ritchie, David S.

“…Poor graft function (PGF), manifested by multilineage cytopenias and complete donor chimerism post-allogeneic stem cell transplantation (alloSCT), and acquired…”
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Venetoclax or Ruxolitinib in Pre-Transplant Conditioning Lowers the Engraftment Barrier by Different Mechanisms in Allogeneic Stem Cell Transplant Recipients by Davis, Joanne E, Du, Kelei, Ludford-Menting, Mandy J, Prabahran, Ashvind, Wong, Eric, Huntington, Nicholas D, Koldej, Rachel M, Ritchie, David S

“…Allogeneic stem cell transplantation (alloSCT) is utilised to cure haematological malignancies through a combination of conditioning regimen intensity and…”
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The economic cost of care in poor graft function following allogeneic stem cell transplantation by Juneja, Manu, Prabahran, Ashvind, Rawicki, Mayani, Chee, Lynette C Y, Koldej, Rachel M, Ritchie, David S

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A phase 1 dose-escalation study of low-dose lenalidomide maintenance post-allogeneic stem cell transplantation for high-risk acute myeloid leukaemia or myelodysplastic syndrome by Koo, Ray Mun, Wong, Eric, Davis, Joanne E., Perera, Travis, Lim, Andrew, Koldej, Rachel M., Ritchie, David S.

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miRNA expression profiling of cerebrospinal fluid in patients with aneurysmal subarachnoid hemorrhage by Stylli, Stanley S, Adamides, Alexios A, Koldej, Rachel M, Luwor, Rodney B, Ritchie, David S, Ziogas, James, Kaye, Andrew H

“…OBJECTIVE MicroRNAs (miRNAs) regulate gene expression and therefore play important roles in many physiological and pathological processes. The aim of this…”
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Impact of age‐, cancer‐, and treatment‐driven inflammation on T cell function and immunotherapy by Quinn, Kylie M., Kartikasari, Apriliana E. R., Cooke, Rachel E., Koldej, Rachel M., Ritchie, David S., Plebanski, Magdalena

“…Many cancers are predominantly diagnosed in older individuals and chronic inflammation has a major impact on the overall health and immune function of older…”
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Refinement of lentiviral vector for improved RNA processing and reduced rates of self inactivation repair by Koldej, Rachel M, Anson, Donald S

“…Lentiviral gene therapy vectors are now finding clinical application. In order to fully exploit their potential it is important that vectors are made as…”
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Venetoclax Dose Escalation Rapidly Activates a BAFF/BCL-2 Survival Axis in Chronic Lymphocytic Leukemia by Luo, Meng-Xiao, Tan, Tania, Trussart, Marie, Poch, Annika, Nguyen, Minh-Hanh Thi, Speed, Terence P, Hicks, Damien G, Bandala-Sanchez, Esther, Peng, Hongke, Chappaz, Stephane, Slade, Charlotte, Utzschneider, Daniel T, Koldej, Rachel M, Ritchie, David, Strasser, Andreas, Thijssen, Rachel, Ritchie, Matthew E, Tam, Constantine Si Lun, Lindeman, Geoffrey J, Huang, Professor, David Ching Siang, Lew, Thomas E, Anderson, Mary Ann, Roberts, Andrew W, Teh, Charis E, Gray, Daniel H D

“…Venetoclax, a first-in-class BH3 mimetic drug targeting BCL-2, has improved outcomes for patients with chronic lymphocytic leukemia (CLL). Early measurements…”
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Immune recovery in patients with mantle cell lymphoma receiving long-term ibrutinib and venetoclax combination therapy by Davis, Joanne E., Handunnetti, Sasanka M., Ludford-Menting, Mandy, Sharpe, Chia, Blombery, Piers, Anderson, Mary Ann, Roberts, Andrew W., Seymour, John F., Tam, Constantine S., Ritchie, David S., Koldej, Rachel M.

“…Combination venetoclax plus ibrutinib for the treatment of mantle cell lymphoma (MCL) has demonstrated efficacy in the relapsed or refractory setting; however,…”
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Comparison of insulators and promoters for expression of the Wiskott-Aldrich syndrome protein using lentiviral vectors by Koldej, Rachel M, Carney, Gael, Wielgosz, Matthew M, Zhou, Sheng, Zhan, Jun, Sorrentino, Brian P, Nienhuis, Arthur W

“…Gene therapy for the treatment of Wiskott-Aldrich syndrome (WAS) presents an alternative to the current use of allogeneic bone marrow transplantation. We…”
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1115. A Simple Method for the Purification of Lentiviral Vectors Using a Combination of Ultrafiltration and Anion Exchange Chromatography by Koldej, Rachel M., Anson, Donald S.

“…Ultrafiltration and anion exchange chromatography have both been proposed as useful scalable purification techniques for the production of lentiviral vectors…”
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Immunologic Basis to Poor Graft Function Following Allogeneic Stem Cell Transplantation by Prabahran, Ashvind Anand, Koldej, Rachel M, Chee, Lynette C.Y., Ritchie, David

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Recurrent CMV Viremia Portends Poor Prognosis and Results in Significant Resource Utilization in Patients with Poor Graft Function Post Allogeneic Stem Cell Transplantation by Prabahran, Ashvind Anand, Chee, Lynette C.Y., Koldej, Rachel M, Yong, Michelle K, Ritchie, David

“…Introduction Poor Graft Function (PGF) characterized by 2 or more lineage cytopenias in the setting of complete donor chimerism is a recognized complication of…”
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Dynamic Immune Surveillance in Durable Clinical Response to Combined BTK and BCL2 Inhibition in MCL at Longitudinal Single-Cell Resolution by Wang, Kevin, Di Liberto, Maurizio, Hu, Yang, Huang, Xiangao, Koldej, Rachel M, Ritchie, David, Martin, Peter, Inghirami, Giorgio, Elemento, Olivier, Tam, Constantine S., Chen-Kiang, Selina

“…Combined inhibition of BTK with ibrutinib and BCL2 with venetoclax is one of the most promising therapies for B cell malignancies, especially mantle cell…”
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ALLG AMLM26 Phase 1B/2 Study Investigating Novel Therapies to Target Early Relapse and Clonal Evolution As Pre-Emptive Therapy in AML (INTERCEPT): A Multi-Arm, Precision-Based, Recursive, Platform Trial by Wei, Andrew H, Iland, Harry J, Reynolds, John, Loo, Sun, Chua, Chong Chyn, Westerman, David, Tiong, Ing S, Ivey, Adam, Blombery, Piers, Anstee, Natasha S, Koldej, Rachel M, Curtis, David J., Kipp, David, Ritchie, David, Ross, David M, Souza, Amanda, Collins, Jenny, Bajel, Ashish, Grove, Carolyn, Marlton, Paula, Roberts, Andrew W, Pemmaraju, Naveen, Patel, Keyur P., Loghavi, Sanam, Konopleva, Marina, Daver, Naval, DiNardo, Courtney D.

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High Deliverability of a Midostaurin Triplet Regimen Incorporating Venetoclax and Low Dose Cytarabine in Non-Adverse Cytogenetic Risk Acute Myeloid Leukaemia: A Sub-Analysis of the Australasian Leukaemia Lymphoma Group (ALLG) Intervene Study by Chua, Chong Chyn, Anstee, Natasha S, Enjeti, Anoop Kumar, Hiwase, Devendra, Marlton, Paula, Bajel, Ashish, Tan, Shuh Ying, Morris, Edward S., Ma, Chun-Kei-Kris, Grove, Carolyn, Cooney, Julian, Beligaswatte, Ashanka, Koldej, Rachel M, Ting, Stephen B, Perera, Travis, Johnston, Amanda, Reynolds, John, Ritchie, David, Wei, Andrew H

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