Search Results - "Kolarova, Julieta"

Circulating levels of cytochrome c after resuscitation from cardiac arrest: a marker of mitochondrial injury and predictor of survival by Radhakrishnan, Jeejabai, Wang, Sufen, Ayoub, Iyad M, Kolarova, Julieta D, Levine, Rita F, Gazmuri, Raúl J

“…Ca(2+) overload and reactive oxygen species can injure mitochondria during ischemia and reperfusion. We hypothesized that mitochondrial injury occurs during…”
Get more information

Limiting sarcolemmal Na+ entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca2+ accumulation and attenuates myocardial injury by Wang, Sufen, Radhakrishnan, Jeejabai, Ayoub, Iyad M, Kolarova, Julieta D, Taglieri, Domenico M, Gazmuri, Raul J

“…Department of Medicine, Division of Critical Care Medicine, and Department of Physiology and Biophysics, Rosalind Franklin University of Medicine and Science;…”
Get full text

Zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism by Ayoub, Iyad M, Kolarova, Julieta D, Kantola, Ronald L, Radhakrishnan, Jeejabai, Wang, Sufen, Gazmuri, Raúl J

“…OBJECTIVE:To investigate whether sodium-hydrogen exchanger isoform-1 (NHE-1) inhibition attenuates myocardial injury during resuscitation from ventricular…”
Get full text

AVE4454B—a novel sodium-hydrogen exchanger isoform-1 inhibitor—compared less effective than cariporide for resuscitation from cardiac arrest by Radhakrishnan, Jeejabai, Kolarova, Julieta D, Ayoub, Iyad M, Gazmuri, Raúl J

“…We compared the efficacy of the novel sodium-hydrogen exchanger (NHE-1) inhibitor AVE4454B with cariporide for resuscitation from ventricular fibrillation (VF)…”
Get full text

Cariporide enables hemodynamically more effective chest compression by leftward shift of its flow-depth relationship by Kolarova, Julieta D, Ayoub, Iyad M, Gazmuri, Raúl J

“…When given during closed-chest resuscitation, cariporide (4-isopropyl-methylsulfonylbenzoyl-guanidine methanesulfonate; a selective inhibitor of the Na(+)/H(+)…”
Get more information

Myocardial protection by erythropoietin during resuscitation from ventricular fibrillation by Singh, Dinesh, Kolarova, Julieta D, Wang, Sufen, Ayoub, Iyad M, Gazmuri, Raúl J

“…Human recombinant erythropoietin (rhEPO) can protect the myocardium during ischemia and reperfusion. We investigated whether rhEPO could ameliorate previously…”
Get full text

Successful ventricular defibrillation by the selective sodium-hydrogen exchanger isoform-1 inhibitor cariporide by GAZMURI, Raul J, AYOUB, Iyad M, HOFFNER, Elizabeth, KOLAROVA, Julieta D

“…Sodium-hydrogen exchanger isoform-1 (NHE-1) activation worsens functional myocardial abnormalities associated with ischemia and reperfusion. We hypothesize…”
Get full text

Myocardial protection during ventricular fibrillation by inhibition of the sodium-hydrogen exchanger isoform-1 by Gazmuri, Raúl J, Ayoub, Iyad M, Kolarova, Julieta D, Karmazyn, Morris

“…Activation of the sarcolemmal sodium-hydrogen exchanger isoform-1 (NHE-1) in response to the intense intracellular acidosis that develops during ischemia has…”
Get full text

Inotropic options for postresuscitation myocardial dysfunction by Gazmuri, Raúl J, Kolarova, Julieta D, Ayoub, Iyad M

Get full text

Cariporide given during resuscitation promotes return of electrically stable and mechanically competent cardiac activity by Ayoub, Iyad M, Kolarova, Julieta, Gazmuri, Raúl J

“…Abstract Episodes of ventricular fibrillation (VF) and myocardial dysfunction commonly occur after cardiac resuscitation compromising the return of stable…”
Get full text

Optimal timing for electrical defibrillation after prolonged untreated ventricular fibrillation by Kolarova, Julieta, Ayoub, Iyad M, Yi, Zhong, Gazmuri, Raúl J

“…OBJECTIVEIt currently is recommended that electrical shocks be delivered immediately on recognition of ventricular fibrillation. However, decreased…”
Get full text

Limiting sarcolemmal Na+ entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca^sup 2+^ accumulation and attenuates myocardial injury by Wang, Sufen, Radhakrishnan, Jeejabai, Ayoub, Iyad M, Kolarova, Julieta D

“…Intracellular ... accumulation during ischemia and reperfusion leads to cytosolic ... overload through reverse-mode operation of the sarcolemmal ... exchanger…”
Get full text

Limiting sarcolemmal Na super(+) entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca super(2+) accumulation and attenuates myocardial injury by Wang, Sufen, Radhakrishnan, Jeejabai, Ayoub, Iyad M, Kolarova, Julieta D, Taglieri, Domenico M, Gazmuri, Raul J

“…Background: intracellular Na super(+) accumulation during ischemia and reperfusion leads to cytosolic Ca super(2+) overload through reverse-mode operation of…”
Get full text

Limiting sarcolemmal Na + entry during resuscitation from ventricular fibrillation prevents excess mitochondrial Ca 2+ accumulation and attenuates myocardial injury by Wang, Sufen, Radhakrishnan, Jeejabai, Ayoub, Iyad M., Kolarova, Julieta D., Taglieri, Domenico M., Gazmuri, Raúl J.

“…Background: intracellular Na + accumulation during ischemia and reperfusion leads to cytosolic Ca 2+ overload through reverse-mode operation of the sarcolemmal…”
Get full text

Sodium-hydrogen exchange inhibition during ventricular fibrillation: Beneficial effects on ischemic contracture, action potential duration, reperfusion arrhythmias, myocardial function, and resuscitability by AYOUB, Iyad M, KOLAROVA, Julieta, ZHONG YI, TREVEDI, Atul, DESHMUKH, Hanumant, LUBELL, David L, FRANZ, Michael R, MALDONADO, Frank A, GAZMURI, Raul J

“…Inhibition of the sarcolemmal sodium-hydrogen exchanger isoform-1 (NHE-1) is emerging as a promising novel strategy for ameliorating myocardial injury…”
Get full text

Cariporide minimizes adverse myocardial effects of epinephrine during resuscitation from ventricular fibrillation by Ayoub, Iyad M, Kolarova, Julieta, Kantola, Ronald L, Sanders, Robert, Gazmuri, Raúl J

“…OBJECTIVE:Epinephrine given during closed-chest resuscitation increases blood flow across the coronary and cerebral circuits. However, epinephrine worsens…”
Get full text

Abstract 606: Myocardial Protection by Glycogen Synthase Kinase-3β Inhibition during Resuscitation from Cardiac Arrest by Radhakrishnan, Jeejabai, Ayoub, Iyad M, Wang, Sufen, Kolarova, Julieta D, Taglieri, Domenico M, Gazmuri, Raúl J

“…Abstract only Background: GSK-3β functions as a “master switch” that is negatively regulated by various cardioprotective mechanisms. GSK-3β is upregulated by…”
Get full text

CARDIOPROTECTION BY ERYTHROPOIETIN DURING RESUSCITATION FROM VENTRICULAR FIBRILLATION: 96 by Ayoub, Iyad M, Kolarova, Julieta D, Wang, Sufen, Gazmuri, Raul J, Singh, Dinesh, Havalad, Suresh H

Get full text

Cariporide potentiates the effects of epinephrine and vasopressin by nonvascular mechanisms during closed-chest resuscitation by Kolarova, Julieta, Yi, Zhong, Ayoub, Iyad M, Gazmuri, Raúl J

“…The efficacy of vasopressor therapy during closed-chest resuscitation is limited and decreases over time. We previously reported that sodium-hydrogen exchanger…”
Get more information

CYTOCHROME C: A NOVEL BIOMARKER FOR PREDICTING SURVIVAL AFTER CARDIAC RESUSCITATION: 94 by Ayoub, Iyad M, Wang, Sufen, Radhakrishnan, Jeejabai, Kolarova, Julieta D, Lyu, Theodore, Carr, Ryan, Gazmuri, Raul J

Get full text