Search Results - "Kolar, Michal"
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Plugging the explicit σ-holes in molecular docking
Published in Chemical communications (Cambridge, England) (01-02-2013)“…A novel approach in molecular docking was successfully used to reproduce protein-ligand experimental geometries. When dealing with halogenated compounds the…”
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2
TCF/LEF Transcription Factors: An Update from the Internet Resources
Published in Cancers (20-07-2016)“…T-cell factor/lymphoid enhancer-binding factor (TCF/LEF) proteins (TCFs) from the High Mobility Group (HMG) box family act as the main downstream effectors of…”
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3
Right versus left ventricular remodeling in heart failure due to chronic volume overload
Published in Scientific reports (24-08-2021)“…Mechanisms of right ventricular (RV) dysfunction in heart failure (HF) are poorly understood. RV response to volume overload (VO), a common contributing factor…”
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4
Linking toxicity profiles to pollutants in sludge and sediments
Published in Journal of hazardous materials (05-01-2017)“…•Constrained correspondence analysis linked contaminant concentrations to toxicity.•In sludge samples Hg, As, HCH, PBDEs and HBCD influenced the toxicity…”
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Computer Modeling of Halogen Bonds and Other σ‑Hole Interactions
Published in Chemical reviews (11-05-2016)“…In the field of noncovalent interactions a new paradigm has recently become popular. It stems from the analysis of molecular electrostatic potentials and…”
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The interplay between peptides and RNA is critical for protoribosome compartmentalization and stability
Published in Nucleic acids research (28-09-2024)“…The ribosome, owing to its exceptional conservation, harbours a remarkable molecular fossil known as the protoribosome. It surrounds the peptidyl transferase…”
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BRAT1 links Integrator and defective RNA processing with neurodegeneration
Published in Nature communications (26-08-2022)“…Mutations in BRAT1 , encoding BRCA1-associated ATM activator 1, have been associated with neurodevelopmental and neurodegenerative disorders characterized by…”
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An evolutionary conserved pattern of 18S rRNA sequence complementarity to mRNA 5' UTRs and its implications for eukaryotic gene translation regulation
Published in Nucleic acids research (01-09-2013)“…There are several key mechanisms regulating eukaryotic gene expression at the level of protein synthesis. Interestingly, the least explored mechanisms of…”
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A systematic computational analysis of the rRNA-3' UTR sequence complementarity suggests a regulatory mechanism influencing post-termination events in metazoan translation
Published in RNA (Cambridge) (01-07-2016)“…Nucleic acid sequence complementarity underlies many fundamental biological processes. Although first noticed a long time ago, sequence complementarity between…”
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10
Glycol porphyrin derivatives and temoporfin elicit resistance to photodynamic therapy by different mechanisms
Published in Scientific reports (15-03-2017)“…The development of drug resistance is a major problem which often occurs during anticancer chemotherapies. Photodynamic therapy (PDT) has been studied as an…”
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Novel PD-L1- and collagen-expressing patient-derived cell line of undifferentiated pleomorphic sarcoma (JBT19) as a model for cancer immunotherapy
Published in Scientific reports (04-11-2023)“…Soft tissue sarcomas are aggressive mesenchymal-origin malignancies. Undifferentiated pleomorphic sarcoma (UPS) belongs to the aggressive, high-grade, and…”
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Plants Rather than Mineral Fertilization Shape Microbial Community Structure and Functional Potential in Legacy Contaminated Soil
Published in Frontiers in microbiology (24-06-2016)“…Plant-microbe interactions are of particular importance in polluted soils. This study sought to determine how selected plants (horseradish, black nightshade…”
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Understanding the Pathogenicity of Burkholderia contaminans, an Emerging Pathogen in Cystic Fibrosis
Published in PloS one (11-08-2016)“…Several bacterial species from the Burkholderia cepacia complex (Bcc) are feared opportunistic pathogens that lead to debilitating lung infections with a high…”
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14
Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium
Published in Scientific reports (07-02-2019)“…The first step in the development of human colorectal cancer is aberrant activation of the Wnt signaling pathway. Wnt signaling hyperactivation is…”
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Unique Gene Expression Signatures in the Intestinal Mucosa and Organoids Derived from Germ-Free and Monoassociated Mice
Published in International journal of molecular sciences (29-03-2019)“…Commensal microbiota contribute to gut homeostasis by inducing transcription of mucosal genes. Analysis of the impact of various microbiota on intestinal…”
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Steady-State Coherences by Composite System-Bath Interactions
Published in Physical review letters (17-08-2018)“…We identify sufficient conditions on the structure of the interaction Hamiltonian between a two-level quantum system and a thermal bath that, without any…”
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17
Complete Genome Sequence of the Haloaromatic Acid-Degrading Bacterium Achromobacter xylosoxidans A8
Published in Journal of Bacteriology (01-02-2011)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The impact of phosphodiesterase‐5 inhibition or angiotensin‐converting enzyme inhibition on right and left ventricular remodeling in heart failure due to chronic volume overload
Published in Pharmacology research & perspectives (01-02-2024)“…While phosphodiesterase‐5 inhibition (PED5i) may prevent hypertrophy and failure in pressure‐overloaded heart in an experimental model, the impact of PDE5i on…”
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19
Combined effect of deformation and artificial aging on mechanical properties of Al–Mg–Si Alloy
Published in Transactions of Nonferrous Metals Society of China (01-08-2012)“…The effect of pre-deformation followed by or together with artificial aging on the mechanical properties as strength and ductility of an AA6060 aluminium alloy…”
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Effect of Pre-Deformation on Mechanical Response of an Artificially Aged Al-Mg-Si Alloy
Published in MATERIALS TRANSACTIONS (01-07-2011)“…In order to investigate the effect of deformation on the artificial aging response of an Al-Mg-Si alloy, a series of tensile tests have been designed and…”
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