Search Results - "Kolanczyk, Richard C."

In vitro metabolism of imidacloprid and acetamiprid in rainbow trout and rat by Kolanczyk, Richard C., Tapper, Mark A., Sheedy, Barbara R., Serrano, Jose A.

“…Providing an alternative to pyrethroids, organophosphates, and carbamates, the neonicotinoids are now the most widely used insecticides in the world. They are…”
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PFAS Biotransformation Pathways: A Species Comparison Study by Kolanczyk, Richard C, Saley, Megan R, Serrano, Jose A, Daley, Sara M, Tapper, Mark A

“…Limited availability of fish metabolic pathways for PFAS may lead to risk assessments with inherent uncertainties based only upon the parent chemical or the…”
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A Comparative Study of Phase I and II Hepatic Microsomal Biotransformation of Phenol in Three Species of Salmonidae: Hydroquinone, Catechol, and Phenylglucuronide Formation by Kolanczyk, Richard C, Solem, Laura E, Schmieder, Patricia K, McKim, 3rd, James M

“…The biotransformation of phenol at 11 °C was studied using pre-spawn adult rainbow ( ) (RBT), brook ( ) (BKT), and lake trout ( ) (LKT) hepatic microsomal…”
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Sex-Linked Changes in Biotransformation of Phenol in Brook Trout (Salvelinus fontinalis) over an Annual Reproductive Cycle by Kolanczyk, Richard C, Solem, Laura E, Tapper, Mark A, Hoffman, Alex D, Sheedy, Barbara R, Schmieder, Patricia K, McKim, James M

“…The microsomal metabolism of phenol (11 °C) over an annual reproductive cycle from June to December was studied using fall spawning adult brook trout…”
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Increased Endocrine Activity of Xenobiotic Chemicals as Mediated by Metabolic Activation by Kolanczyk, Richard C., Denny, Jeffrey S., Sheedy, Barbara R., Olson, Victoria V., Serrano, Jose A., Tapper, Mark A.

“…Abstract The US Environmental Protection Agency (USEPA) is faced with long lists of chemicals that require hazard assessment. The present study is part of a…”
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Conversion of Estrone to 17β‐Estradiol: A Potential Confounding Factor in Assessing Risks of Environmental Estrogens to Fish by Tapper, Mark A., Kolanczyk, Richard C., LaLone, Carlie A., Denny, Jeffrey S., Ankley, Gerald T.

“…Feminization of male fish and the role of endocrine‐active chemicals in this phenomenon has been an area of intense study for many years. Estrone (E1), a…”
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In vitro metabolism assessment of thiacloprid in rainbow trout and rat by LC-UV and high resolution-mass spectrometry by Serrano, Jose, Kolanczyk, Richard C., Blackwell, Brett R., Sheedy, Barbara R., Tapper, Mark A.

“…Thiacloprid (THI) is a widely used neonicotinoid insecticide where concerns have been raised regarding low absorption by crops, substantial distribution in…”
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Use of Trout Liver Slices To Enhance Mechanistic Interpretation of Estrogen Receptor Binding for Cost-Effective Prioritization of Chemicals within Large Inventories by Schmieder, Patricia K, Tapper, Mark A, Denny, Jeffrey S, Kolanczyk, Richard C, Sheedy, Barbara R, Henry, Tala R, Veith, Gilman D

“…The cost of testing chemicals as reproductive toxicants precludes the possibility of evaluating large chemical inventories without a robust strategy for…”
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A comparison of fish pesticide metabolic pathways with those of the rat and goat by Kolanczyk, Richard C., Serrano, Jose A., Tapper, Mark A., Schmieder, Patricia K.

“…Ecological risk assessments are often limited in their ability to consider metabolic transformations for fish species due to a lack of data. When these types…”
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Characterization and analysis of estrogenic cyclic phenone metabolites produced in vitro by rainbow trout liver slices using GC-MS, LC-MS and LC-TOF-MS by Serrano, Jose, Kolanczyk, Richard C., Tapper, Mark A., Lahren, Tylor, Dongari, Nagaraju, Hammermeister, Dean E., Kosian, Patricia A., Schmieder, Patricia K., Sheedy, Barbara R., Challis, Katie, Kubátová, Alena

“…Cyclic phenones are chemicals of interest to the USEPA and international organizations due to their potential for endocrine disruption to aquatic and…”
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Estrogenic activity of multicyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss) in vitro assays by Kolanczyk, Richard C., Denny, Jeffrey S., Sheedy, Barbara R., Schmieder, Patricia K., Tapper, Mark A.

“…A representative group of multicyclic aromatic hydrocarbons (MAHC) which can be further classified as bridged-ring (bridged-MAHC) or fused-ring (fused-MAHC)…”
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Metabolism of cyclic phenones in rainbow trout in vitro assays by Serrano, Jose, Tapper, Mark A., Kolanczyk, Richard C., Sheedy, Barbara R., Lahren, Tylor, Hammermeister, Dean E., Denny, Jeffrey S., Hornung, Michael W., Kubátová, Alena, Kosian, Patricia A., Voelker, Jessica, Schmieder, Patricia K.

“…1. Cyclic phenones are chemicals of interest to the USEPA due to their potential for endocrine disruption to aquatic and terrestrial species. 2. Prior to this…”
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MetaPath: An electronic knowledge base for collating, exchanging and analyzing case studies of xenobiotic metabolism by Kolanczyk, Richard C., Schmieder, Patricia, Jones, William J., Mekenyan, Ovanes G., Chapkanov, Atanas, Temelkov, Stanislav, Kotov, Stefan, Velikova, Maria, Kamenska, Verginia, Vasilev, Krasimir, Veith, Gilman D.

“…► MetaPath compiles metabolism paths and data for regulatory assessments and modeling purposes. ► MetaPath provides data analysis tools for all data fields…”
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Functional models for catechol 1,2-dioxygenase. Structure, reactivity, and mechanism by Que, Lawrence, Kolanczyk, Richard C, White, Lloyd S

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Rate and capacity of hepatic microsomal ring-hydroxylation of phenol to hydroquinone and catechol in rainbow trout ( Oncorhynchus mykiss) by Kolanczyk, Richard C, Schmieder, Patricia K

“…Rainbow trout ( Oncorhynchus mykiss) liver microsomes were used to study the rate of ring-hydroxylation of phenol at 11 and 25 °C by directly measuring the…”
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Effects of anesthesia (tricaine methanesulfonate, MS222) on liver biotransformation in rainbow trout ( Oncorhynchus mykiss) by Kolanczyk, Richard C, Fitzsimmons, Patrick N, McKim, James M, Erickson, Russell J, Schmieder, Patricia K

“…The effect of tricaine methanesulfonate (MS222) on rainbow trout liver biotransformation rates was investigated with a microsomal model; an in vitro…”
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An in vivo microdialysis method for the qualitative analysis of hepatic phase I metabolites of phenol in rainbow trout ( Oncorhynchus mykiss) by Solem, Laura E, Kolanczyk, Richard C, McKim, James M

“…Development of reliable and accurate methodologies for determination of xenobiotic hepatic biotransformation rate and capacity parameters is important to the…”
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The catalytic effect of bovine serum albumin on the ortho rearrangement of the potential ultimate carcinogen, N-(sulfooxy)-2-(acetylamino)fluorene, generated enzymically from N-hydroxy-2-(acetylamino)fluorene and evidence for substrate specificity of the enzymic sulfonation of arylhydroxamic acids by Kolanczyk, Richard C, Rutks, Indulis R, Gutmann, Helmut R

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Effect of bovine serum albumin on the extent of ortho rearrangement of N-(sulfooxy)-2-fluorenylacetamide and of enzymatically activated N-hydroxy-2-fluorenylacetamide and on the binding of reactive esters to nucleic acids by Kolanczyk, Richard C, Gutmann, Helmut R, Rutks, Indulis R

“…We have investigated the effect of the bovine serum albumin (BSA)-catalyzed ortho rearrangement of synthetic and enzymatically generated…”
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Dynamics of renal excretion of phenol and major metabolites in the rainbow trout ( Oncorhynchus mykiss) by McKim, James M., Kolanczyk, Richard C., Lien, Gregory J., Hoffman, Alex D.

“…Renal excretion of phenol (PH), phenyl glucuronide (PG), phenyl sulfate (PS), and hydroquinone (HQ) was determined in 600–900 g rainbow trout ( Oncorhynchus…”
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